WNT6 anticorps (Middle Region)
Aperçu rapide pour WNT6 anticorps (Middle Region) (ABIN405845)
Antigène
Voir toutes WNT6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human WNT6
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anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (Internal Region) antibody
WNT6 Reactivité: Humain, Boeuf (Vache), Chien, Lapin, Cheval, Roussette (Chauve-souris) IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (AA 1-365) antibodyWNT6 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (AA 1-365) antibodyWNT6 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (AA 281-365) antibodyWNT6 Reactivité: Humain, Souris WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (N-Term) antibodyWNT6 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Hamster IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (AA 252-301) antibodyWNT6 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (Middle Region) antibodyWNT6 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (AA 173-201) antibodyWNT6 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 365 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
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Autre désignation
- WNT6
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Sujet
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The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365 -
Poids moléculaire
- 37 kDa
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ID gène
- 7475
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NCBI Accession
- NM_006522, NP_006513
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UniProt
- Q9Y6F9
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Pathways
- Signalisation WNT, Tube Formation
Antigène
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