SLIT1 anticorps (AA 487-504)
Aperçu rapide pour SLIT1 anticorps (AA 487-504) (ABIN401297)
Antigène
Voir toutes SLIT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 487-504
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Specificité
- This antibody is directed against SLIT-1 protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Rat, Human, Chicken Frog.
Species reactivity (tested):Mouse. -
Purification
- Affinity chromatography
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Immunogène
- Synthetic peptide corresponding aa 487-504 of mouse SLIT-1 protein
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Isotype
- IgG
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anti-Slit Homolog 1 (SLIT1) (AA 603-773) antibody
SLIT1 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 647-835) antibodySLIT1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 308-512) antibodySLIT1 Reactivité: Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 84-113) antibodySLIT1 Reactivité: Humain, Souris WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 84-113), (N-Term) antibodySLIT1 Reactivité: Souris WB, IHC (p) Hôte: Lapin Polyclonal RB32325 unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 611-791) antibodySLIT1 Reactivité: Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 1170-1184), (Secreted) antibodySLIT1 Reactivité: Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 455-500) antibodySLIT1 Reactivité: Humain WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 1315-1534) antibodySLIT1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 1439-1488) antibodySLIT1 Reactivité: Humain, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio), Roussette (Chauve-souris), Singe WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.2 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- SLIT1 (Slit Homolog 1 (SLIT1))
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Autre désignation
- SLIT1
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Sujet
- SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.Synonyms: KIAA0813, MEGF4, Multiple epidermal growth factor-like domains protein 4, SLIL1, SLIT-1, Slit homolog 1 protein
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ID gène
- 20562
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NCBI Accession
- NP_056563
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UniProt
- Q80TR4
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Pathways
- Regulation of Cell Size
Antigène
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