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TRKB anticorps (AA 1-429)

Cet anticorps anti-TRKB Polyclonal Lapin (ABIN337266) détecte spécifiquement TRKB dans WB, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.
N° du produit ABIN337266
779,18 €
Plus frais de livraison 40,00 € et TVA
50 μg
Destination: France
Envoi sous 15 à 20 jours ouvrables

Aperçu rapide pour TRKB anticorps (AA 1-429) (ABIN337266)

Antigène

Voir toutes TRKB (NTRK2) Anticorps
TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Reactivité

  • 194
  • 124
  • 111
  • 6
  • 6
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Humain, Rat, Souris

Hôte

  • 175
  • 45
  • 2
  • 1
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 127
  • 99
Polyclonal

Conjugué

  • 119
  • 11
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp TRKB est non-conjugé

Application

  • 166
  • 118
  • 52
  • 51
  • 33
  • 32
  • 27
  • 20
  • 15
  • 14
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 26
    • 22
    • 16
    • 16
    • 14
    • 13
    • 12
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-429

    Specificité

    Recognizes rat TrkB, Mr 145kD, as well as an additional protein, Mr ~90kD, which is likely a TrkB degradation product. Species sequence homology: mouse 97 % and human 88 %.

    Purification

    Protein A purified

    Immunogène

    The entire extracellular domain (corresponding to residues 1-429) of the rat TrkB receptor, expressed in COS cells.

    Type of Immunogen: Cells

    Isotype

    IgG
  • Indications d'application

    Approved: IHC, IHC-P (10 μg/mL), WB (0.5 - 2 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Western Blot: 0.5-2 μg/mL detected TrkB in mouse brain membrane protein preparations.

    Commentaires

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    0.1M Tris-glycine,  pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

    Autre désignation

    NTRK2 / TRKB

    Sujet

    Name/Gene ID: NTRK2
    Subfamily: Trk/Ror
    Family: Protein Kinase

    Synonyms: NTRK2, gp145-TrkB, Trk-B, TRKB, Tropomyosin-related kinase B, TrkB tyrosine kinase, Tyrosine kinase receptor B

    ID gène

    4915

    UniProt

    Q16620

    Pathways

    Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport
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