ITGA6 anticorps
Aperçu rapide pour ITGA6 anticorps (ABIN118234)
Antigène
Voir toutes ITGA6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises the CD49f-antigen, (VLA-6 alpha-chain). This antibody reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In Immunohistology this clone reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor. This clone has been reported to inhibit platelet adhesion to Laminin. (3)
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Purification
- Affinity Chromatography on Protein G
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Immunogène
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
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Isotype
- IgG2a
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anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibody
ITGA6 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 Reactivité: Humain WB, FACS, IHC, ELISA, IF Hôte: Souris Monoclonal 129CT49-6-5 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1043-1072), (Isoform 2) antibodyITGA6 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB15309 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1082-1110), (C-Term) antibodyITGA6 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB18006 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Ser1064) antibodyITGA6 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 24-133) antibodyITGA6 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 4C1 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1-1073) antibodyITGA6 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (N-Term) antibodyITGA6 Reactivité: Humain, Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 625-866) antibodyITGA6 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (PE)ITGA6 Reactivité: Rat FACS Hôte: Souris Monoclonal Mab-5A PE
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Indications d'application
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Flow cytometry. Immunohistochemistry on frozen sections. Recommended positive control tissue: Human Tonsil. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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Autre désignation
- CD49f / ITGA6
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Sujet
- CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
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ID gène
- 3655
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NCBI Accession
- NP_000201
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UniProt
- P23229
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Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
Antigène
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