anti-Angiomotin Like 2 (AMOTL2) Anticorps

AMOTL2 belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. De plus, nous expédions Angiomotin Like 2 Protéines (4) et Angiomotin Like 2 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
AMOTL2 51421 Q9Y2J4
AMOTL2 65157  
AMOTL2 56332 Q8K371
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Top anti-Angiomotin Like 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 19 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in A375 cell line lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of AMOTL2 Antibody (Center) (ABIN652806) in mouse liver tissue lysates (35 µg/lane). AMOTL2 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué ICC, IF Immunocytochemistry/Immunofluorescence: AMOTL2 Antibody  - Staining of human cell line CACO-2 shows localization to centrosome & cell junctions. 100 μL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of AMOTL2 Antibody in A375 cell line lysates (35ug/lane) Western blot analysis of AMOTL2 Antibody in mouse liver tissue lysates (35ug/lane) 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg Connectez-vous pour afficher 7 to 9 Days
$390.50
Détails
Humain Lapin Inconjugué WB   200 μL Connectez-vous pour afficher 11 to 16 Days
$594.00
Détails
Humain Lapin APC ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin HRP ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin PE ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin FITC ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin Inconjugué WB   50 μg Connectez-vous pour afficher 2 to 3 Days
$473.93
Détails

AMOTL2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,


, , , , ,
Rat (Rattus)


Mouse (Murine) ,


anti-Angiomotin Like 2 Anticorps mieux référencés

  1. Human Polyclonal AMOTL2 Primary Antibody pour WB - ABIN652806 : Bratt, Wilson, Troyanovsky, Aase, Kessler, Van Meir, Holmgren, Meir: Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. dans Gene 2002 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Angiomotin Like 2 partenaires d’interaction

Zebrafish Angiomotin Like 2 (AMOTL2) interaction partners

  1. Amotl2a function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 (Montrer YAP1 Anticorps) and the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) effector Lef1 (Montrer LEF1 Anticorps).

  2. amotL2 associates to the VE-cadherin adhesion complex where it couples adherens junctions to contractile actin fibres.

  3. We demonstrate that amotl2 knockdown in zebrafish wild-type embryos results in embryonic dorsalization, and this effect can be antagonized by co-knockdown of the dorsal inducer beta-catenin2.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Amotl2 interacts preferentially with and facilitates translocation of the phosphorylated c-Src (Montrer SRC Anticorps), which may in turn regulate the membrane architecture. These data provide the first evidence that amotl2 is essential for cell movements in vertebrate embryos.

Human Angiomotin Like 2 (AMOTL2) interaction partners

  1. these results provide novel insights into a dual tumor suppressive function of AMOTL2 by targeting both YAP (Montrer YAP1 Anticorps) and AKT (Montrer AKT1 Anticorps) in liver size control and cancer prevention

  2. study reports for the first time that USP9X (Montrer USP9X Anticorps) is a deubiquitinase of Angiomotin-like 2 (AMOTL2) and that AMOTL2 mono-ubiquitination is required for YAP (Montrer YAP1 Anticorps) inhibition

  3. mTORC2 (Montrer CRTC2 Anticorps)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (Montrer YAP1 Anticorps) signaling.

  4. AmotL2 expression correlates with loss of tissue architecture in tumors from human breast and colon cancer patients.

  5. Scaffold proteins angiomotin (Amot (Montrer AMOT Anticorps)) and angiomotin (Montrer AMOT Anticorps)-related AmotL1 (Montrer AMOTL1 Anticorps) and AmotL2 were recently identified as negative regulators of YAP (Montrer YAP1 Anticorps) and TAZ (Montrer TAZ Anticorps) by preventing their nuclear translocation.

  6. These results collectively suggest that the Hippo pathway negatively regulates the actin-binding activity of Amot (Montrer AMOT Anticorps) family members through direct phosphorylation.

  7. These results demonstrate a role for Amotl2 in synaptic maturation and support the involvement of podosomes in this process.

  8. AMOTL2 interacts with TAZ (Montrer TAZ Anticorps) and modulates transcriptional activity of TAZ (Montrer TAZ Anticorps).

  9. AMOTL2 is as a novel activator of LATS2 (Montrer LATS2 Anticorps).

  10. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

Mouse (Murine) Angiomotin Like 2 (AMOTL2) interaction partners

  1. mTORC2 (Montrer CRTC2 Anticorps)-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP (Montrer YAP1 Anticorps) signaling.

  2. AmotL2 disrupts apical-basal cell polarity and promotes tumor invasion.

  3. Amot (Montrer AMOT Anticorps), Amotl1 (Montrer AMOTL1 Anticorps), and Amotl2 are differentially expressed in uterine cells during the peri (Montrer POSTN Anticorps)-implantation period.

  4. Amotl2 plays a pivotal role in polarity, migration and proliferation of angiogenic endothelial cells

  5. Data show that MUPP1 (Montrer MPDZ Anticorps) interacts with angiomotin (Amot (Montrer AMOT Anticorps)), JEAP (Montrer AMOTL1 Anticorps)/Amot (Montrer AMOT Anticorps)-like 1 and MASCOT/Amot (Montrer AMOT Anticorps)-like 2, and that all the Amot (Montrer AMOT Anticorps)/JEAP (Montrer AMOTL1 Anticorps) family proteins also interacted with Patj (Montrer INADL Anticorps), a close relative of MUPP1 (Montrer MPDZ Anticorps).

Angiomotin Like 2 (AMOTL2) profil antigène

Profil protéine

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.

Gene names and symbols associated with AMOTL2

  • angiomotin like 1 (AMOTL1) anticorps
  • angiomotin like 2a (amotl2a) anticorps
  • angiomotin like 1 (amotl1) anticorps
  • angiomotin like 1 L homeolog (amotl1.L) anticorps
  • angiomotin like 2 (AMOTL2) anticorps
  • angiomotin like 2 (amotl2) anticorps
  • angiomotin like 2 (Amotl2) anticorps
  • angiomotin-like 2 (Amotl2) anticorps
  • amotl2 anticorps
  • AW549739 anticorps
  • C79691 anticorps
  • cb308 anticorps
  • DKFZp468L222 anticorps
  • jeap anticorps
  • Lccp anticorps
  • MASCOT anticorps
  • mKIAA0989 anticorps
  • sb:cb308 anticorps
  • wu:fc41b07 anticorps
  • wu:fc64c06 anticorps

Protein level used designations for AMOTL2

angiomotin like 1 , angiomotin-like protein 1 , angiomotin like 2 , angiomotin-like 2a , angiomotin-like protein 1-like , angiomotin-like protein 2-like , Leman coiled-coil protein , angiomotin-like protein 2

GENE ID SPECIES
428091 Gallus gallus
451491 Pan troglodytes
558920 Danio rerio
100145436 Xenopus (Silurana) tropicalis
100158429 Xenopus laevis
100172648 Pongo abelii
100348712 Oryctolagus cuniculus
100475663 Ailuropoda melanoleuca
718868 Macaca mulatta
100379727 Xenopus (Silurana) tropicalis
100523696 Sus scrofa
460712 Pan troglodytes
100540953 Meleagris gallopavo
51421 Homo sapiens
65157 Rattus norvegicus
56332 Mus musculus
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