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AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. De plus, nous expédions Angiotensin II Receptor-Associated Protein Anticorps (48) et Angiotensin II Receptor-Associated Protein Protéines (4) et beaucoup plus de produits pour cette protéine.
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A role for AT1 receptor-associated proteins in blood pressure regulation
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R (Montrer AGTR1 Kits ELISA), plays a protective role against the development of systemic insulin (Montrer INS Kits ELISA) resistance via regulatory effects on adipose tissue function.
The phosphatidylinositol transfer protein (Montrer PITPNA Kits ELISA) RdgBbeta (Montrer PITPNC1 Kits ELISA) binds 14-3-3 (Montrer YWHAQ Kits ELISA) via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).
the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.
CSF (Montrer CSF2 Kits ELISA) angiotensin II, ACE (Montrer ACE Kits ELISA), and ACE2 (Montrer ACE2 Kits ELISA) levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 (Montrer AQP4 Kits ELISA) antibody, reflecting severe destruction of perivascular astrocytes
Small interfering RNA significantly attenuates angiotensin II type 1 receptor (Montrer AGTR1 Kits ELISA)-stimulated inositol phosphate formation.
cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein
isolation of a novel protein, ARAP1 (Montrer ARAP1 Kits ELISA), which promotes recycling of angiotensin(1A) to the plasma membrane in HEK (Montrer EPHA3 Kits ELISA)-293 cells
CAML (Montrer CAMLG Kits ELISA) is an important signal transducer for the actions of Ang II (Montrer AGT Kits ELISA) in regulating the calcineurin (Montrer PPP3CA Kits ELISA)-NFAT (Montrer NFATC1 Kits ELISA) pathway and the interaction of CAML (Montrer CAMLG Kits ELISA) with ATRAP may mediate the Ang II (Montrer AGT Kits ELISA) actions in vascular physiology
Identify Atrap as a novel regulatory protein (Montrer TGFB1 Kits ELISA) of the cardiac Ca(2+)-ATPase SERCA2a (Montrer CA-P60A Kits ELISA). Suggest that Atrap enhances the activity of SERCA2a (Montrer ATP2A2 Kits ELISA) and, consequently, facilitates ventricular relaxation.
These results suggest that increased formation of AT1R-P2Y6R (Montrer P2RY6 Kits ELISA) heterodimers with age may increase the likelihood of hypertension induced by Ang II (Montrer AGT Kits ELISA).
although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct
Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.
AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.
The inhibition of degradation of angiotensin II type 1 receptor (Montrer AGTR1 Kits ELISA)-associated protein (Montrer BCAP31 Kits ELISA) (ATRAP) and inactivation of AT1R-mediated p38 MAPK (Montrer MAPK14 Kits ELISA) and STAT3 (Montrer STAT3 Kits ELISA) signaling pathways, are involved cardiac hypertrophy.
Activation of aortic vascular ATRAP partially inhibits the Nox4 (Montrer NOX4 Kits ELISA)/p22(phox (Montrer CYBA Kits ELISA))-ROS (Montrer ROS1 Kits ELISA)-p38MAPK (Montrer MAPK14 Kits ELISA)/JNK (Montrer MAPK8 Kits ELISA) pathway and pathological aortic hypertrophy provoked by Ang II (Montrer AGT Kits ELISA)-mediated hypertension.
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin (Montrer INS Kits ELISA) resistance via regulatory effects on adipose tissue function.
AGTRAP expression is regulated by USF1 (Montrer USF1 Kits ELISA) and USF2 (Montrer USF2 Kits ELISA)
renal tubule-dominant ATRAP activation provokes no evident effects on blood pressure at baseline but exerts an inhibitory effect on the pathological elevation of blood pressure in response to angiotensin II stimulation
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
angiotensin II receptor-associated protein
, type-1 angiotensin II receptor-associated protein
, Type-1 angiotensin II receptor-associated protein
, AT1 receptor-associated protein
, ATI receptor-associated protein
, angiotensin II, type I receptor-associated protein
, AT1 receptor
, angiotensin II receptor, type I