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The protein encoded by BSP is a major structural protein of the bone matrix. De plus, nous expédions Bone Sialoprotein Kits (34) et et beaucoup plus de produits pour cette protéine.
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These data indicate that secretome derived from salivary gland cancer cells can influence the expression of two potential biomarkers of oral cancer-namely, bone sialoprotein (Montrer CRISP1 Anticorps) (BSP (Montrer KLK6 Anticorps)) and dentin sialoprotein (DSP (Montrer DSPP Anticorps))-in normal salivary gland cells.
In conclusion, serum levels of BSP, ALP, ICTP, and PSA increased in patients with bone metastases, and combined detection of all markers could improve the positive-predictive value.
Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2 (Montrer RUNX2 Anticorps)-Osterix (Montrer SP7 Anticorps)-BSP (Montrer KLK6 Anticorps) Signaling.
Two significant SNPs within IBSP (Montrer IBSP Anticorps), rs1054627 and rs17013181, were associated with BMD (Montrer BEST1 Anticorps) and postmenopausal osteoporosis by the two-stage strategy, and rs17013181 was also significantly associated with serum IBSP (Montrer IBSP Anticorps) levels.
Our results suggest that SSEA (Montrer MPST Anticorps)-4 is a specific cell surface antigen (Montrer CD53 Anticorps) that can be used to identify dental pulp stem cells.
the strong correlation between bone sialoprotein (Montrer CRISP1 Anticorps) and OPN (Montrer SPP1 Anticorps) and papillary thyroid carcinoma suggests a role for BSP (Montrer KLK6 Anticorps) and OPN (Montrer SPP1 Anticorps) in calcification and tumor progression of papillary thyroid carcinoma
oxidized low-density lipoprotein-induced expression dependent on Runx2 (Montrer RUNX2 Anticorps) expression
Bone sialoprotein (Montrer CRISP1 Anticorps) could be a key mediator of the hypertrophic chondrocytes-induced angiogenesis of osteoarthritis.
Current evidence demonstrates that BSP (Montrer KLK6 Anticorps) and OPN (Montrer SPP1 Anticorps), play significant roles in bone metastasis of osteotropic malignancies derived from breast, prostate, lung, thyroid, and multiple myeloma. [review]
High expression of bone sialoprotein (Montrer CRISP1 Anticorps) in breast neoplasms was associated with cytokeratin (Montrer KRT4 Anticorps)-positive cells in bone marrow, but not with lymph node metastasis.
Bone marrow ablation in BSP (Montrer KLK6 Anticorps)-/- mice is followed by a faster vascular and hematopoietic recolonization, along with lower medullary bone formation. Thus, lack of BSP (Montrer KLK6 Anticorps) affects the interplay between hematopoiesis, angiogenesis, and osteogenesis, maybe in part through higher expression of VEGF (Montrer VEGFA Anticorps) and the angiogenic SIBLING, OPN (Montrer SPP1 Anticorps).
a bone sialoprotein (Montrer CRISP1 Anticorps)-null bone microenvironment affects the hematopoietic system both quantitatively and qualitatively
full expression of either OPN (Montrer SPP1 Anticorps) or BSP (Montrer KLK6 Anticorps) is necessary for the anabolic effect of PTH (Montrer PTH Anticorps) at least in the ectopic calvaria injection model
BSP (Montrer KLK6 Anticorps) plays a non-redundant role in acellular cementum formation, likely involved in initiating mineralization on the root surface. Through its importance to cementum integrity, BSP (Montrer KLK6 Anticorps) is essential for periodontal function.
Lack of BSP (Montrer KLK6 Anticorps) affects both osteoclast formation and activity.
bone sialoprotein (Montrer CRISP1 Anticorps) has a role in neoplasm metastasis
BSP (Montrer KLK6 Anticorps) gene transcription is autoregulated in part by a positive feedback on its own promoter.
Bsp (Montrer KLK6 Anticorps) mRNA is expressed in developing testis cords and thus may contribute to testis differentiation
BSP (Montrer KLK6 Anticorps) contributes to RANKL (Montrer TNFSF11 Anticorps)-mediated bone resorption by inducing osteoclastogenesis and osteoclast survival and decreasing osteoclast apoptosis
Stimulation with EMD (Montrer EMD Anticorps) significantly (P < .01) enhanced mRNA expression of BSP (Montrer KLK6 Anticorps) up to 13.9-fold.
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
, bone sialoprotein 2
, bone sialoprotein II
, cell-binding sialoprotein
, integrin binding sialoprotein
, integrin-binding sialoprotein
, integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)
, Bone sialoprotein 2