anti-Ceramide Synthase 2 (CERS2) Anticorps

CERS2 encodes a protein that has sequence similarity to yeast longevity assurance gene 1. De plus, nous expédions Ceramide Synthase 2 Kits (6) et Ceramide Synthase 2 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CERS2 29956 Q96G23
CERS2 76893 Q924Z4
CERS2 310667  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-Ceramide Synthase 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-LASS2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$412.50
Détails
Cobaye Lapin Inconjugué IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with LASS2 antibody ABIN462181 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with LASS2 antibody ABIN462181 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (67.32 KDa) . 200 μL Connectez-vous pour afficher 11 to 12 Days
$430.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Cobaye Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Anti-Ceramide synthase 2 Polyclonal Antibody, Unconjugated (ABIN709331) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Ceramide synthase 2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$295.90
Détails
Humain Souris Inconjugué WB Western Blot analysis of LASS2 expression in transfected 293T cell line by LASS2 MaxPab polyclonal antibody.<br><br>Lane 1: LASS2 transfected lysate(41.8 KDa).<br>Lane 2: Non-transfected lysate.<br> LASS2 MaxPab polyclonal antibody. Western Blot analysis of LASS2 expression in human placenta. 50 μg Connectez-vous pour afficher 11 to 12 Days
$430.00
Détails

CERS2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human ,
,
,
, , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , , ,

anti-Ceramide Synthase 2 Anticorps mieux référencés

  1. Human Monoclonal CERS2 Primary Antibody pour ELISA, WB - ABIN526190 : Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells. dans Anticancer research 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CERS2 Primary Antibody pour WB - ABIN526188 : Jensen, Calvert, Volpert, Kouri, Hurley, Luciano, Wu, Chalastanis, Futerman, Stegh: Bcl2L13 is a ceramide synthase inhibitor in glioblastoma. dans Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

Plus d’anticorps contre Ceramide Synthase 2 partenaires d’interaction

Human Ceramide Synthase 2 (CERS2) interaction partners

  1. ASGR1 (Montrer ASGR1 Anticorps) can inhibit the activity of V-ATPase (Montrer ATP6V1H Anticorps) by interacting with LASS2, thereby suppressing the metastatic potential of hepatoma cells.

  2. Data show that 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9 (Montrer AGPAT9 Anticorps)) inhibit cell growth by regulating expression of KLF4 (Montrer KLF4 Anticorps)/LASS2/V-ATPase (Montrer ATP6V1H Anticorps) proteins in breast cancer.

  3. these results indicate that miR (Montrer MLXIP Anticorps)-9 upregulation might be associated with malignant phenotype of bladder cancer. miR (Montrer MLXIP Anticorps)-9 promotes chemoresistance of bladder cancer cells by target LASS2.

  4. Data show that CERS2 expression was markedly different between various breast cancer cells and inversely correlated with cell invasion.

  5. silencing of TMSG1 increased V-ATPase (Montrer ATP6V1H Anticorps) activity, decreased extracellular pH and in turn the activation of secreted MMP-2 (Montrer MMP2 Anticorps), which ultimately promoted metastasis capacity of breast cancer cell.

  6. Results confirmed that TMSG1 is a potential metastasis suppressor gene, and suggested that the mechanism involved the induction of apoptosis and inhibition of cell proliferation via a caspase (Montrer CASP3 Anticorps)-dependent mitochondrial pathway.

  7. the vacuolar ATPase (V-ATPase (Montrer DNAH8 Anticorps)) activity and extracellular hydrogen ion concentration were significantly decreased and the activity of secreted matrix metalloproteinase-2 (MMP-2 (Montrer MMP2 Anticorps)) was downregulated in MCF-7 cells overexpressing LASS2/TMSG1

  8. the inhibitory effect of the LASS2 on growth, invasion and metastasis of prostate cancer cells

  9. Co-expression of CerS2 with CerS4 (Montrer CERS4 Anticorps)/CerS6 (Montrer CERS6 Anticorps) reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation.

  10. expression and role of ceramide synthase-2 in the lung

Mouse (Murine) Ceramide Synthase 2 (CERS2) interaction partners

  1. LASS2 plays an important role in efficient liver regeneration in response to partial hepatectomy.

  2. Deletion of CerS2 strongly reduced very long-chain ceramides (Cer24:0, 24:1) but concomitantly increased long-chain ceramides and sphinganine in plasma and colon tissue. In naive CerS2(-/-) mice, the expression of tight junction proteins including ZO-1 (Montrer TJP1 Anticorps) was almost completely lost in the colon epithelium, leading to increased membrane permeability. Ceramide synthase 2 deficiency aggravates dextran induced colitis in mice.

  3. this study shows that Cers2 limits the levels of S1P (Montrer S1PR1 Anticorps) in thymus and blood to maintain functional S1P (Montrer S1PR1 Anticorps) gradients that mediate thymocyte emigration into the circulation

  4. that only LCBs, the substrates common for all of the CerS isoforms, but not ceramides and complex sphingolipids, were restored to the wild-type levels in the Cers2-rescued Cers1 (Montrer CERS1 Anticorps) mutant mouse brains.

  5. CerS1 (Montrer CERS1 Anticorps), -2, and -6 are hyperacetylated in the mitochondria of SIRT3 (Montrer SIRT3 Anticorps)-null mice.

  6. Haploinsufficiency for this enzyme altered the pattern of ceramide acylation in the liver without affecting total ceramide levels, replacing very-long-chain ceramides with long-chain C16-ceramides.

  7. Development of pheochromocytoma in ceramide synthase 2 null mice

  8. our data strongly indicate that G-CSF (Montrer CSF3 Anticorps)-induced CXCR2 (Montrer CXCR2 Anticorps) expression is regulated in a CerS2-dependent manner and that CerS2 thereby promotes the migration of neutrophils, thus, contributing to inflammation and the development of EAE and MS.

  9. Data indicate that the augmented rate of death of ceramide synthase 2 (CerS2) null mice is due to elevated levels of tumor necrosis factor alpha (TNFalpha (Montrer TNF Anticorps)) secretion as a result of enhanced activity of TNFalpha (Montrer TNF Anticorps)-converting enzyme (TACE (Montrer ADAM17 Anticorps)).

  10. CerS2-deficient kidneys were completely depleted of phytosphingosine-containing cortical sulfatides without any compensatio

Ceramide Synthase 2 (CERS2) profil antigène

Profil protéine

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with CERS2

  • ceramide synthase 2 (CERS2) anticorps
  • ceramide synthase 2 (Cers2) anticorps
  • 0610013I17Rik anticorps
  • AI225939 anticorps
  • L3 anticorps
  • Lass2 anticorps
  • SP260 anticorps
  • TMSG1 anticorps
  • TRH3 anticorps

Protein level used designations for CERS2

LAG1 homolog, ceramide synthase 2 , LAG1 longevity assurance 2 , longevity assurance (LAG1, S. cerevisiae) homolog 2 , tumor metastasis-suppressor gene 1 protein , LAG1 longevity assurance homolog 2 , TRAM homolog 3 , longevity assurance homolog 2 , translocating chain-associating membrane protein homolog 3

GENE ID SPECIES
100055037 Equus caballus
29956 Homo sapiens
483187 Canis lupus familiaris
539223 Bos taurus
76893 Mus musculus
310667 Rattus norvegicus
100156737 Sus scrofa
Fournisseurs de qualité sélectionnés pour anti-Ceramide Synthase 2 (CERS2) Anticorps
Avez-vous cherché autre chose?