anti-Chemokine Binding Protein 2 (CCBP2) Anticorps

CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. De plus, nous expédions CCBP2 Protéines (4) et CCBP2 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CCBP2 1238 O00590
CCBP2 59289 O08707
CCBP2 140473  
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Top anti-CCBP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 93 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC, WB Human Muscle WB Suggested Anti-CCBP2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué IHC (p), WB The anti-CCBP2 N-term Pab (ABIN388745) is used in Western blot to detect CCBP2 in mouse liver tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-CCBP2 Pab (ABIN388746) in mouse small intestine tissue lysate. CCBP2 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Rat Inconjugué FACS Detection of CC Chemokine Receptor D6 in NS0 Mouse Cell Line Transfected with Human CC Chemokine Receptor D6 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody. Detection of CC Chemokine Receptor D6 in NS0 Mouse Cell Line Transfected with Human CC Chemokine Receptor D6 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody. 500 μg Connectez-vous pour afficher 4 to 5 Days
335,00 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué IF, ELISA Immunofluorescence analysis of A549 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué IHC (p) Brain, Purkinje neurons 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails

CCBP2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) , ,
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Rat (Rattus)


anti-CCBP2 Anticorps mieux référencés

  1. Human Polyclonal CCBP2 Primary Antibody pour EIA, IHC (p) - ABIN357386 : Kunkel, Kim, Lazarus, Vierra, Soler, Bowman, Butcher: CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. dans The Journal of clinical investigation 2003 (PubMed)
    Show all 5 references for 357386

  2. Human Polyclonal CCBP2 Primary Antibody pour IHC (p), WB - ABIN388746 : Fra, Locati, Otero, Sironi, Signorelli, Massardi, Gobbi, Vecchi, Sozzani, Mantovani: Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6. dans Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 references for 388746

  3. Human Monoclonal CCBP2 Primary Antibody pour FACS - ABIN4899116 : Martinez de la Torre, Buracchi, Borroni, Dupor, Bonecchi, Nebuloni, Pasqualini, Doni, Lauri, Agostinis, Bulla, Cook, Haribabu, Meroni, Rukavina, Vago, Tedesco, Vecchi, Lira, Locati, Mantovani: Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. dans Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for 4899116

  4. Human Polyclonal CCBP2 Primary Antibody pour IHC (p), WB - ABIN388745 : Soler, Humphreys, Spinola, Campbell: CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. dans Blood 2003 (PubMed)
    Show all 3 references for 388745

  5. Human Polyclonal CCBP2 Primary Antibody pour IHC, WB - ABIN2779383 : Galliera, Jala, Trent, Bonecchi, Signorelli, Lefkowitz, Mantovani, Locati, Haribabu: beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. dans The Journal of biological chemistry 2004 (PubMed)

Plus d’anticorps contre CCBP2 partenaires d’interaction

Human Chemokine Binding Protein 2 (CCBP2) interaction partners

  1. Data show the structural motifs in the atypical chemokine receptor (Montrer CCR1 PLURAL_@9242@) 2 (ACKR2) are responsible for ligand binding, and suggest ACKR2-derived N-terminal peptides as being of potential therapeutic significance.

  2. engagement of the ACR (Montrer ACR Anticorps) D6 by its ligands activates a beta (Montrer SUCLA2 Anticorps)-arrestin1 (Montrer ARRB1 Anticorps)-dependent, G protein-independent signaling pathway that results in the phosphorylation of the actin-binding protein (Montrer KPTN Anticorps) cofilin (Montrer CFL1 Anticorps) through the Rac1-PAK1 (Montrer PAK1 Anticorps)-LIMK1 (Montrer LIMK1 Anticorps) cascade.

  3. co-expression of DARC (Montrer DARC Anticorps), D6, and CCX-CKR (Montrer CCRL1 Anticorps) significantly associated with higher survival in gastric cancer

  4. CCL2 binding to primary adult human astrocytes is CCR2-independent and is likely to be mediated via the D6 decoy.

  5. D6 is expressed in AMs (Montrer MAT1A Anticorps) from patients with COPD (Montrer ARCN1 Anticorps), and its expression correlates with the degree of functional impairment and markers of immune activation.

  6. Chemokine (Montrer CCL1 Anticorps) decoy receptor D6 limits CC-chemokine (Montrer CCL1 Anticorps)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.

  7. DARC (Montrer DARC Anticorps) and D6, the most studied members of this group of molecules, are reviewed.

  8. CCR10 (Montrer CCR10 Anticorps) is unlikely to be necessary for cutaneous homing of TH cells in the models studied here. CCR10 (Montrer CCR10 Anticorps) may instead play a role in the movement of specialized "effector" cutaneous TH cells to and/or within epidermal microenvironments.

  9. CCR10 and its mucosal epithelial ligand CCL28 have roles in the migration of circulating IgA plasmablasts

  10. D6 is constitutively internalized via a ligand-independent, phosphorylation-independent association with beta-arrestin.

Mouse (Murine) Chemokine Binding Protein 2 (CCBP2) interaction partners

  1. ACKR4 on stromal cells aids the egress of antigen presenting cells from mouse skin, and, during inflammation, facilitates CCR7 (Montrer CCR7 Anticorps)-dependent cell trafficking by scavenging CCL19 (Montrer CCL19 Anticorps).

  2. The data shows a novel function for the chemokine receptor (Montrer CCR1 Anticorps) CCX-CKR (Montrer CCRL1 Anticorps) as a regulator of TGF-beta1 (Montrer TGFB1 Anticorps) expression and epithelial-mesenchymal transition in breast cancer cells.

  3. CCRL1 (Montrer CCRL1 Anticorps) is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.

  4. Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.

  5. stepwise acquisition of chemokine (C-C motif) receptor-like 1 (CCRL1 (Montrer CCRL1 Anticorps)) is a late determinant of cortical thymic epithelial cell differentiation

  6. some cells, including plasmacytoid dendritic cells, can express both CCR2 (Montrer CCR2 Anticorps) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (Montrer CCL2 Anticorps)-scavenging potential in vitro and in vivo; and that CCR2 (Montrer CCR2 Anticorps) is a much more effective CCL2 (Montrer CCL2 Anticorps) scavenger than ACKR2.

  7. found that lymph node fringes indeed contained physiological gradients of the chemokine (Montrer CCL1 Anticorps) CCL21 (Montrer CCL21 Anticorps), which depended on the expression of CCRL1 (Montrer CCRL1 Anticorps), the atypical receptor for the CCR7 (Montrer CCR7 Anticorps) ligands CCL19 (Montrer CCL19 Anticorps) and CCL21 (Montrer CCL21 Anticorps)

  8. CCX-CKR (Montrer CCRL1 Anticorps) deletion increases incidence of a spontaneous Sjogren's syndrome-like pathology, suggestive of a defect in self-tolerance. CCX-CKR (Montrer CCRL1 Anticorps)(-/-) mice have fewer thymic epithelial cells per thymocyte, with defects in thymocyte distribution & frequency.

  9. Chemokine (Montrer CCL1 Anticorps) decoy receptor D6 limits CC-chemokine (Montrer CCL1 Anticorps)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.

  10. control of CCR2 ligands by D6 regulates the traffic of Ly6C(high) monocytes and controls their immunosuppressive potential.

CCBP2 profil antigène

Profil protéine

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members\; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Gene names and symbols associated with CCBP2

  • chemokine binding protein 2 (CCBP2) anticorps
  • atypical chemokine receptor 2 (ACKR2) anticorps
  • chemokine binding protein 2 (LOC100219492) anticorps
  • chemokine binding protein 2 (LOC100230349) anticorps
  • chemokine binding protein 2 (LOC100345678) anticorps
  • chemokine receptor D6 (LOC733624) anticorps
  • atypical chemokine receptor 2 (Ackr2) anticorps
  • atypical chemokine receptor 4 (Ackr4) anticorps
  • A630091E18Rik anticorps
  • AI464239 anticorps
  • Ccbp2 anticorps
  • CCR9 anticorps
  • CCR10 anticorps
  • CCR11 anticorps
  • Ccrl1 anticorps
  • CCX-CKR anticorps
  • CCX-CKR1 anticorps
  • Cmkbr9 anticorps
  • Cmkbrl1 anticorps
  • D6 anticorps
  • hD6 anticorps
  • LOC733624 anticorps
  • PPR1 anticorps
  • VSHK1 anticorps

Protein level used designations for CCBP2

chemokine binding protein 2 , chemokine-binding protein 2 , chemokine receptor D6 , C-C chemokine receptor D6 , CC-chemokine-binding receptor JAB61 , chemokine (C-C motif) receptor 9 , chemokine (C-C) receptor 9 , chemokine receptor CCR-10 , chemokine receptor CCR-9 , chemokine-binding protein D6 , D6 beta-chemokine receptor , CCR10-related receptor , C-C CKR-11 , C-C chemokine receptor type 11 , CC chemokine receptor-like 1 , CC-CKR-11 , CCR-11 , CCX CKR , chemokine (C-C motif) receptor-like 1 , chemokine (C-C) receptor-like 1 , chemokine receptor CCR11

GENE ID SPECIES
420393 Gallus gallus
460298 Pan troglodytes
485618 Canis lupus familiaris
512583 Bos taurus
100219492 Taeniopygia guttata
100230349 Taeniopygia guttata
100345678 Oryctolagus cuniculus
733624 Sus scrofa
100589553 Nomascus leucogenys
1238 Homo sapiens
59289 Mus musculus
140473 Rattus norvegicus
252837 Mus musculus
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