anti-Desmin (DES) Anticorps

DES encodes a muscle-specific class III intermediate filament. De plus, nous expédions Desmin Kits (62) et Desmin Protéines (26) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DES 1674 P17661
DES 64362 P48675
DES 13346 P31001
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Top anti-Desmin Anticorps sur anticorps-enligne.fr

Showing 10 out of 412 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-DES Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from K562 cells, using Desmin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Desmin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HeLa/HepG2 cells, using Desmin (Ab-60) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Desmin (Ab-60) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué IHC (p), WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$313.50
Détails
Poulet Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of Desmin staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Desmin staining in human muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-Desmin Antibody (t16) (ABIN389226) in NCI-H460 cell line lysates (35 µg/lane).Desmin-pT16(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Cat Souris Inconjugué ICC, IF, MA, WB Monoclonal Anti-Desmin antibody produced in mouse 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$381.94
Détails
Poulet Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Desmin Polyclonal Antibody, Unconjugated (ABIN736566) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse heart tissue labeled with Anti-Desmin Polyclonal Antibody, Unconjugated (ABIN736566) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$307.45
Détails
Poulet Souris Inconjugué IF, WB Western blot analysis of desmin. Mouse muscle lysate was probed with anti-desmin (clone RD301, ABIN967294) at concentrations 0.25 (lane 1), 0.125 (lane 2), and 0.06 µg/ml (lane 3). Desmin is identified as a band of ~53 kDa. 50 μg Connectez-vous pour afficher 6 to 8 Days
$185.43
Détails

DES Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Desmin Anticorps mieux référencés

  1. Human Monoclonal Desmin Primary Antibody pour IHC (p), WB - ABIN3043640 : Jiang, Xu, Zhu, Chen, Qian, Qiao, Yang, Wang, Chen: Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells. dans Oncology reports 2006 (PubMed)
    Show all 17 Pubmed References

  2. Human Polyclonal Desmin Primary Antibody pour IHC (fro), IHC (p) - ABIN3043265 : Longxi, Buwu, Yuan, Sinan: Expression of p53 in the effects of artesunate on induction of apoptosis and inhibition of proliferation in rat primary hepatic stellate cells. dans PLoS ONE 2011 (PubMed)
    Show all 17 Pubmed References

  3. Human Polyclonal Desmin Primary Antibody pour ICC, IF - ABIN4304974 : Rasmussen, Kweon, Diekmann, Belema-Bedada, Song, Bowlin, Shi, Ferdous, Li, Kyba, Metzger, Koyano-Nakagawa, Garry: ER71 directs mesodermal fate decisions during embryogenesis. dans Development (Cambridge, England) 2011 (PubMed)
    Show all 8 Pubmed References

  4. Human Monoclonal Desmin Primary Antibody pour IHC (fro), IHC - ABIN335226 : Dispersyn, Geuens, Ver Donck, Ramaekers, Borgers: Adult rabbit cardiomyocytes undergo hibernation-like dedifferentiation when co-cultured with cardiac fibroblasts. dans Cardiovascular research 2001 (PubMed)
    Show all 8 Pubmed References

  5. Human Monoclonal Desmin Primary Antibody pour IHC (fro), IHC - ABIN335360 : Pieper, Schaart, Krimpenfort, Henderik, Moshage, van de Kemp, Ramaekers, Berns, Bloemendal: Transgenic expression of the muscle-specific intermediate filament protein desmin in nonmuscle cells. dans The Journal of cell biology 1989 (PubMed)
    Show all 8 Pubmed References

  6. Chicken Polyclonal Desmin Primary Antibody pour IF (p), IHC (p) - ABIN736566 : Luo, Wu, Ye, Li, Hao, Kong, Zheng, Lin, Nie, Zhang: The transient expression of miR-203 and its inhibiting effects on skeletal muscle cell proliferation and differentiation. dans Cell death & disease 2014 (PubMed)
    Show all 5 Pubmed References

  7. Chicken Monoclonal Desmin Primary Antibody pour IF, WB - ABIN967294 : Broers, Carney, Klein Rot, Schaart, Lane, Vooijs, Ramaekers: Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. dans Journal of cell science 1987 (PubMed)
    Show all 4 Pubmed References

  8. Human Polyclonal Desmin Primary Antibody pour ELISA, IHC - ABIN4304973 : Raghuvanshi, Reed, Blaner, Harrison: Cellular localization of β-carotene 15,15' oxygenase-1 (BCO1) and β-carotene 9',10' oxygenase-2 (BCO2) in rat liver and intestine. dans Archives of biochemistry and biophysics 2015 (PubMed)
    Show all 2 Pubmed References

  9. Cat (Feline) Monoclonal Desmin Primary Antibody pour ICC, IF - ABIN257974 : Agarwal, van den Born, van Goor, Navis, Gans, Bakker: Renoprotective effects of long-term oral nicotine in a rat model of spontaneous proteinuria. dans American journal of physiology. Renal physiology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal Desmin Primary Antibody pour IHC, ELISA - ABIN965993 : Shardonofsky, Capetanaki, Boriek: Desmin modulates lung elastic recoil and airway responsiveness. dans American journal of physiology. Lung cellular and molecular physiology 2006 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Desmin partenaires d’interaction

Zebrafish Desmin (DES) interaction partners

  1. Desmin intermediate filaments are required for normal active force generation.

  2. Desmin distribution during muscle maturation changes from dispersed aggregates to a perinuclear concentration to striated (Montrer NSDHL Anticorps) afterwards.

Human Desmin (DES) interaction partners

  1. Targeted sequencing revealed trigenic mutations: c.700G>A/p.E234K in DES, c.2966G>A/p.R989H in MYPN (Montrer MYPN Anticorps), and c.5918G>C/p.R1973P in CACNA1C (Montrer CACNA1C Anticorps) in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome.

  2. demonstrate that the expression of mutant desmin causes disruption of the extrasarcomeric desmin cytoskeleton and extensive mitochondrial abnormalities regarding subcellular distribution, number and shape

  3. Mutation in the Core Structure of Desmin Intermediate Filaments Affects Myoblast Elasticity

  4. Data show that the filament elongation of both desmin and keratin K8/K18 (Montrer KRT18 Anticorps) proceeds very similar to that of vimentin (Montrer VIM Anticorps).

  5. Cdk1 (Montrer CDK1 Anticorps)-induced desmin phosphorylation is required for efficient separation of desmin-IFs and generally detected in muscular mitotic cells in vivo.

  6. Desmin, Lamin A/C, MMP9, and histone H4 were upregulated in the placental villi of women experiencing early pregnancy loss.

  7. Increasing desmin abnormalities were correlated with diastolic dysfunction progression.

  8. expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners

  9. Results propose that the mutations affect desmin structure and cause its aberrant folding and subsequent aggregation, triggering disruption of myofibrils organization.

  10. identified disruption of the desmin system in gastrocnemius myofibers as an index of the myopathy and limitation of muscle function in patients with peripheral artery disease.

Mouse (Murine) Desmin (DES) interaction partners

  1. demonstrate that the expression of mutant desmin causes disruption of the extrasarcomeric desmin cytoskeleton and extensive mitochondrial abnormalities regarding subcellular distribution, number and shape

  2. The disease-mutant desmin variants E245D and T453I exhibited increased binding affinity for nebulette (Montrer NEBL Anticorps), delayed filament assembly kinetics, and caused significant weakening of networks.

  3. desmin and alphaBeta-crystallin are localized at sarcoplasmic reticulum (SR)-mitochondria-associated membranes (MAMs), where they interact with VDAC, Mic60 - the core component of mitochondrial contact site and cristae organizing system (MICOS) complex - and ATP synthase, suggesting that these associations could be crucial in mitoprotection at different levels.

  4. Complete lack or markedly decreased expression of mutant R349P desmin impairs the structural and functional integrity of neuromuscular endplates.

  5. Cdk1 (Montrer CDK1 Anticorps)-induced desmin phosphorylation is required for efficient separation of desmin-IFs and generally detected in muscular mitotic cells in vivo.

  6. the coordinated up-regulations of desmin and alpha- actinin (Montrer ACTN1 Anticorps) specifically in the early stage of diastolic heart failure mouse models indicate a novel myocardial response.

  7. E413K mutation induces desmin network disorganization, desmin aggregate formation and alters the traction forces generation of single myoblasts.

  8. This study identifies desmin as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  9. found that inhibition of the Rac1 pathway (a G protein signaling pathway involved in diverse cellular processes), antioxidant treatment, and stimulation of macroautophagy reduced desmin aggregation by up to 75% in this model

  10. This demonstration of biomechanical integration by the desmin intermediate filament system suggests that it plays an active biological role in muscle in addition to its accepted structural role

Cow (Bovine) Desmin (DES) interaction partners

  1. Results show that expression of desmin increased during the late fattening stage of of hanwoo steers and it contributes to the muscle contractile apparatus.

Desmin (DES) profil antigène

Profil protéine

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Gene names and symbols associated with anti-Desmin (DES) Anticorps

  • desmin (DES) anticorps
  • desmin, gene 1 L homeolog (des.1.L) anticorps
  • desmin, gene 1 (des.1) anticorps
  • desmin (des) anticorps
  • desmin a (desma) anticorps
  • desmin (Des) anticorps
  • desmin b (desmb) anticorps
  • desmin, gene 1 S homeolog (des.1.S) anticorps
  • desmin, gene 2 S homeolog (des.2.S) anticorps
  • cb290 anticorps
  • cmd1i anticorps
  • CSM1 anticorps
  • CSM2 anticorps
  • des anticorps
  • des-a anticorps
  • des-b anticorps
  • desm anticorps
  • desmin anticorps
  • fb59a12 anticorps
  • LGMD2R anticorps
  • LOC100220724 anticorps
  • MGC52614 anticorps
  • MGC75911 anticorps
  • MGC80853 anticorps
  • wu:fb59a12 anticorps
  • wu:fc11d08 anticorps
  • zgc:109859 anticorps
  • zgc:154009 anticorps

Protein level used designations for anti-Desmin (DES) Anticorps

desmin , desmin, gene 1 , desmin-like , intermediate filament protein , muscle-specific intermediate filament desmin , fc11d08

GENE ID SPECIES
100059397 Equus caballus
100137488 Papio anubis
446868 Xenopus laevis
394739 Xenopus (Silurana) tropicalis
470657 Pan troglodytes
100136041 Oncorhynchus mykiss
100220724 Taeniopygia guttata
100402007 Callithrix jacchus
30148 Danio rerio
100586972 Nomascus leucogenys
395906 Gallus gallus
1674 Homo sapiens
64362 Rattus norvegicus
497091 Canis lupus familiaris
13346 Mus musculus
101097010 Felis catus
280765 Bos taurus
101117308 Ovis aries
100328890 Oryctolagus cuniculus
396725 Sus scrofa
100733478 Cavia porcellus
101837949 Mesocricetus auratus
768287 Danio rerio
379869 Xenopus laevis
733312 Xenopus laevis
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