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DES encodes a muscle-specific class III intermediate filament. De plus, nous expédions Desmin Kits (59) et Desmin Protéines (27) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 404 products:
Chicken Polyclonal Desmin Primary Antibody pour IF (p), IHC (p) - ABIN736566
Luo, Wu, Ye, Li, Hao, Kong, Zheng, Lin, Nie, Zhang: The transient expression of miR-203 and its inhibiting effects on skeletal muscle cell proliferation and differentiation. dans Cell death & disease 2014
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Chicken Monoclonal Desmin Primary Antibody pour IF, WB - ABIN967294
Broers, Carney, Klein Rot, Schaart, Lane, Vooijs, Ramaekers: Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. dans Journal of cell science 1987
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Human Monoclonal Desmin Primary Antibody pour IHC (p), WB - ABIN1106974
Tidball: Desmin at myotendinous junctions. dans Experimental cell research 1992
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Human Monoclonal Desmin Primary Antibody pour IHC (fro), IF - ABIN1106980
Seidal, Kindblom, Angervall: Myoglobin, desmin and vimentin in ultrastructurally proven rhabdomyomas and rhabdomyosarcomas. An immunohistochemical study utilizing a series of monoclonal and polyclonal antibodies. dans Applied pathology 1988
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Human Polyclonal Desmin Primary Antibody pour EIA, WB - ABIN357901
Li, Lilienbaum, Butler-Browne, Paulin: Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development. dans Gene 1989
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Human Polyclonal Desmin Primary Antibody pour IHC, ELISA - ABIN334386
Chen, Chang, Trivedi, Capetanaki, Cryns: Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis. dans The Journal of biological chemistry 2003
Cow (Bovine) Polyclonal Desmin Primary Antibody pour WB - ABIN2776842
Fidziańska, Kotowicz, Sadowska, Goudeau, Walczak, Vicart, Hausmanowa-Petrusewicz: A novel desmin R355P mutation causes cardiac and skeletal myopathy. dans Neuromuscular disorders : NMD 2005
Human Polyclonal Desmin Primary Antibody pour IHC (p), WB - ABIN389226
Ariza, Coll, Fernández-Figueras, López, Mate, García, Fernández-Vasalo, Navas-Palacios: Desmin myopathy: a multisystem disorder involving skeletal, cardiac, and smooth muscle. dans Human pathology 1995
Cow (Bovine) Polyclonal Desmin Primary Antibody pour WB - ABIN2776843
Pica, Kathirvel, Pramono, Lai, Yee: Characterization of a novel S13F desmin mutation associated with desmin myopathy and heart block in a Chinese family. dans Neuromuscular disorders : NMD 2008
Desmin intermediate filaments are required for normal active force generation.
Desmin distribution during muscle maturation changes from dispersed aggregates to a perinuclear concentration to striated (Montrer NSDHL Anticorps) afterwards.
demonstrate that the expression of mutant desmin causes disruption of the extrasarcomeric desmin cytoskeleton and extensive mitochondrial abnormalities regarding subcellular distribution, number and shape
Mutation in the Core Structure of Desmin Intermediate Filaments Affects Myoblast Elasticity
Data show that the filament elongation of both desmin and keratin K8/K18 (Montrer KRT18 Anticorps) proceeds very similar to that of vimentin (Montrer VIM Anticorps).
Cdk1 (Montrer CDK1 Anticorps)-induced desmin phosphorylation is required for efficient separation of desmin-IFs and generally detected in muscular mitotic cells in vivo.
Desmin, Lamin A/C, MMP9, and histone H4 were upregulated in the placental villi of women experiencing early pregnancy loss.
Increasing desmin abnormalities were correlated with diastolic dysfunction progression.
expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners
Results propose that the mutations affect desmin structure and cause its aberrant folding and subsequent aggregation, triggering disruption of myofibrils organization.
identified disruption of the desmin system in gastrocnemius myofibers as an index of the myopathy and limitation of muscle function in patients with peripheral artery disease.
The desmin intermediate filament network plays a major role in striated (Montrer NSDHL Anticorps) muscle development and maintenance by integrating and coordinating most cellular components necessary for proper mechanochemical signaling, organelle cross-talk, energy production and trafficking processes required for proper tissue homeostasis. [Review]
The disease-mutant desmin variants E245D and T453I exhibited increased binding affinity for nebulette (Montrer NEBL Anticorps), delayed filament assembly kinetics, and caused significant weakening of networks.
desmin and alphaBeta-crystallin are localized at sarcoplasmic reticulum (SR)-mitochondria-associated membranes (MAMs), where they interact with VDAC, Mic60 - the core component of mitochondrial contact site and cristae organizing system (MICOS) complex - and ATP synthase, suggesting that these associations could be crucial in mitoprotection at different levels.
Complete lack or markedly decreased expression of mutant R349P desmin impairs the structural and functional integrity of neuromuscular endplates.
the coordinated up-regulations of desmin and alpha- actinin (Montrer ACTN1 Anticorps) specifically in the early stage of diastolic heart failure mouse models indicate a novel myocardial response.
E413K mutation induces desmin network disorganization, desmin aggregate formation and alters the traction forces generation of single myoblasts.
This study identifies desmin as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients
found that inhibition of the Rac1 pathway (a G protein signaling pathway involved in diverse cellular processes), antioxidant treatment, and stimulation of macroautophagy reduced desmin aggregation by up to 75% in this model
This demonstration of biomechanical integration by the desmin intermediate filament system suggests that it plays an active biological role in muscle in addition to its accepted structural role
Results show that expression of desmin increased during the late fattening stage of of hanwoo steers and it contributes to the muscle contractile apparatus.
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
, desmin, gene 1
, intermediate filament protein
, muscle-specific intermediate filament desmin