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anti-FK506 Binding Protein 8, 38kDa (FKBP8) Anticorps

The protein encoded by FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. De plus, nous expédions FK506 Binding Protein 8, 38kDa Protéines (7) et FK506 Binding Protein 8, 38kDa Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FKBP8 14232 O35465
FKBP8 290652 Q3B7U9
FKBP8 23770 Q14318
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Top anti-FK506 Binding Protein 8, 38kDa Anticorps sur anticorps-enligne.fr

Showing 10 out of 118 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FKBP8 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, WB 25 μL Connectez-vous pour afficher 8 to 10 Days
209,00 €
Détails
Boeuf (Vache) Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué WB FKBP8 Antibody (Center) (ABIN652170) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FKBP8 antibody detected the FKBP8 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 25 μL Connectez-vous pour afficher 5 to 7 Days
157,14 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of FKBP-38 with mouse intestine tissue lysate (left lane) and Jurkat cell lysate (Right lane). 100 μg Connectez-vous pour afficher 6 to 8 Days
337,56 €
Détails
Humain Lapin Inconjugué WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 100 μg Connectez-vous pour afficher 5 to 7 Days
412,76 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails

FKBP8 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-FK506 Binding Protein 8, 38kDa Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal FKBP8 Primary Antibody pour WB - ABIN2782773 : Okamoto, Omori, Kaname, Abe, Nishimura, Suzuki, Miyamura, Yoshimori, Moriishi, Matsuura: A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication. dans Journal of virology 2008 (PubMed)

  2. Human Polyclonal FKBP8 Primary Antibody pour EIA, WB - ABIN401052 : Portier, Taglialatela: Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression. dans The Journal of biological chemistry 2006 (PubMed)

Plus d’anticorps contre FK506 Binding Protein 8, 38kDa partenaires d’interaction

Mouse (Murine) FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. Our findings thus indicate that the FKBP38-ANKMY2 (Montrer ANKMY2 Anticorps) axis plays a key role in regulation of Shh (Montrer SHH Anticorps) signaling in vivo.

  2. In pre-hearing time Fkbp8-specific signal was also observed in the tectorial membrane, whose alpha- and beta-Tectorin (Montrer TECTB Anticorps) components show similar time-dependent expression of mRNA as Fkbp8.

  3. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8, and subsequently for Fkbp1a (Montrer FKBP1A Anticorps).

  4. Results show that FKBP8 is an essential antagonist of sonic hedgehog (Montrer SHH Anticorps) signaling in central nervous system development.

  5. FKBP38 functions to anchor the 26S proteasome (Montrer Psmd4 Anticorps) at the organellar membrane

  6. Gene expression analysis of Fkbp8 mutants revealed a perturbation of expression of neural tube patterning genes, suggesting that endogenous FKBP8 activity establishes dorso-ventral patterning of the neural tube.

  7. Findings suggest that FKBP38 is required for neuroectodermal organization during neural tube formation as a result of its anti-apoptotic activity and regulation of neurite extension

  8. Disruption of FKBP8 function activates the Shh (Montrer SHH Anticorps) signaling pathway cell-autonomously dependent on the Gli2 (Montrer GLI2 Anticorps) transcription factor and kinesin-2 (Montrer KIF2A Anticorps) subunit Kif3a (Montrer KIF3A Anticorps), a component of the intraflagellar transport machinery used to generate cilia.

  9. Data indicate that PHD2 (Montrer EGLN1 Anticorps) protein stability is regulated by a ubiquitin-independent proteasomal pathway involving FKBP38 as adaptor protein that mediates proteasomal interaction.

Human FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. The information presented here provides important clues for understanding the catalytic activity of FKBP38, its regulation by the unique N-terminal extension, and the potential calcium- and calmodulin (Montrer CALM1 Anticorps)-mediated activation of FKBP38.

  2. Overexpression of permanently active S100P (Montrer S100P Anticorps) in Huh-7 cells inhibited the interaction of FKBP38 with Bcl-2 (Montrer BCL2 Anticorps), resulting in the suppression of Bcl-2 (Montrer BCL2 Anticorps) stability

  3. FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR (Montrer CFTR Anticorps)) folding and stability

  4. The derived structure model of the complex between Bcl-2 (Montrer BCL2 Anticorps) and the FKBP38 catalytic domain features both electrostatic and hydrophobic intermolecular contacts and provides a rationale for the regulation of the FKBP38/Bcl-2 (Montrer BCL2 Anticorps) interaction by Ca(2 (Montrer CA2 Anticorps)+).

  5. Data support a dual role for FKBP38 in regulating CFTR (Montrer CFTR Anticorps) synthesis and post-translational folding.

  6. a dual mechanism for PA activation of mTORC1: PA displaces FKBP38 from mTOR (Montrer FRAP1 Anticorps) and allosterically stimulates the catalytic activity of mTORC1.

  7. this charge-sensitive site in the FKBP (Montrer FKBP7 Anticorps) domain participates in the regulation of FKBP38 function by enabling electrostatic interactions with ligand proteins and/or salt ions such as Ca(2 (Montrer CA2 Anticorps)+)

  8. These results demonstrate that FKBP38 is a novel regulator of the oncogenic protein PRL-3 abundance and that alteration in the stability of PRL-3 can have a dramatic impact on cell proliferation.

  9. novel insights into the structural arrangement of FKBP38/calmodulin (Montrer CALM1 Anticorps) complex

  10. FKBP38 is a key player in regulating the function of Bcl-2 (Montrer BCL2 Anticorps) by antagonizing caspase (Montrer CASP3 Anticorps)-dependent degradation through the direct interaction with the flexible loop domain of Bcl-2 (Montrer BCL2 Anticorps), which contains the caspase (Montrer CASP3 Anticorps) cleavage site

FK506 Binding Protein 8, 38kDa (FKBP8) profil antigène

Profil protéine

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.

Gene names and symbols associated with FKBP8

  • FK506 binding protein 8, 38kDa (FKBP8) anticorps
  • FK506 binding protein 8, 38kDa (fkbp8) anticorps
  • FK506-binding protein 8 (fkbp8) anticorps
  • FK506 binding protein 8 (Fkbp8) anticorps
  • FK506 binding protein 8 (fkbp8) anticorps
  • 38kDa anticorps
  • FKBP-8 anticorps
  • FKBP-38 anticorps
  • fkbp8 anticorps
  • FKBP38 anticorps
  • FKBPr38 anticorps
  • zgc:77672 anticorps

Protein level used designations for FKBP8

peptidyl-prolyl cis-trans isomerase FKBP8 , FK506 binding protein 8, 38kDa , peptidyl-prolyl cis-trans isomerase FKBP8-like , FK506-binding protein 8 , 38 kDa FK506-binding protein , 38 kDa FKBP , FK506-binding protein 38 , FKBPR38 , PPIase FKBP8 , mFKBP38 , rotamase , FK506-binding protein 8 (38kD) , FKBP-38 , FKBP-8 , hFKBP38

GENE ID SPECIES
420123 Gallus gallus
455862 Pan troglodytes
100145724 Xenopus (Silurana) tropicalis
100443356 Pongo abelii
100194916 Salmo salar
14232 Mus musculus
290652 Rattus norvegicus
393858 Danio rerio
23770 Homo sapiens
484819 Canis lupus familiaris
512356 Bos taurus
495188 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-FK506 Binding Protein 8, 38kDa (FKBP8) Anticorps
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