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LGALS9 was initially thought to represent a pseudogene of galectin 9; however, this transcript has good exon-intron structure and encodes a predicted protein of the same size as and highly similar to galectin 9. De plus, nous expédions Lectin, Galactoside-Binding, Soluble, 9 Kits (58) et Lectin, Galactoside-Binding, Soluble, 9 Protéines (35) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 197 products:
Human Polyclonal LGALS9 Primary Antibody pour ELISA, WB - ABIN561667
Bellac, Coimbra, Simon, Imboden, Leib: Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. dans Neurobiology of disease 2007
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Mouse (Murine) Polyclonal LGALS9 Primary Antibody pour CyTOF, FACS - ABIN4899254
Iqbal, Sampaio, Maione, Greco, Niki, Hirashima, Perretti, Cooper: Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. dans The American journal of pathology 2011
in a model of experimental autoimmune encephalomyelitis, we show that an agonist of DR3 (Montrer TNFRSF25 Anticorps) suppressed disease, correlating with expansion of CD4 (Montrer CD4 Anticorps)+Foxp3 (Montrer FOXP3 Anticorps)+ Tregs, and this protective effect was lost in Galectin-9-/- mice
Galectin 9 is a novel dectin 1 (Montrer CLEC7A Anticorps) ligand in pancreatic ductal adenocarcinoma. Upon disruption of the dectin 1 (Montrer CLEC7A Anticorps)-galectin 9 axis, CD4 (Montrer CD4 Anticorps)(+) and CD8 (Montrer CD8A Anticorps)(+) T cells, which are dispensable for PDA progression in hosts with an intact signaling axis, become reprogrammed into indispensable mediators of anti-tumor immunity.
The Gal-9/Tim-3 (Montrer HAVCR2 Anticorps) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.
These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.
galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.
Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury
Gal-9, a natural TIM-3 (Montrer HAVCR2 Anticorps) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.
Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (Montrer HAVCR2 Anticorps) independent manner.
galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (Montrer TGFB1 Anticorps) to enforce iTreg cell differentiation and maintenance.
Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.
Significantly elevated Gal-9 levels were found in both minimal-mild (I-II) and moderate-severe (III-IV) stages of endometriosis in comparison with healthy controls.
We investigated tumor-infiltrating CD4 (Montrer CD4 Anticorps) and CD8 (Montrer CD8A Anticorps) T cells and the expression of PD-L1 (Montrer CD274 Anticorps), Galectin-9, and XAGE1 (Montrer XAGE1A Anticorps) in stage I to IIIA lung adenocarcinomas using a tissue microarray to deduce their contribution to overall survival, and our data showed that PD-L1 (Montrer CD274 Anticorps) expression was a positive indicator, whereas Galectin-9 and XAGE1 (Montrer XAGE1A Anticorps) expression was negative.
Tim3 (Montrer HAVCR2 Anticorps)/Gal-9 alleviates the inflammation of TAO patients via suppressing Akt (Montrer AKT1 Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway.
Low Gal-9 expression is associated with pancreatic and ampullary cancer.
X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site has been presented.
These findings may indicate that an increase in the Gal-9 level, a novel immune checkpoint molecule, can reflect immune-related adverse effects of various biotherapies.
Our data suggest a role of galectin-9 in regulating HIV transcription and viral production in vivo during therapy
these data suggest that the high Tim-3 (Montrer HAVCR2 Anticorps) expression in monocytes could be utilized by tumor-promoting Gal-9 expression on CD4 (Montrer CD4 Anticorps)(+) T cells
this study shows that in osteosarcoma patients, Tim3 (Montrer HAVCR2 Anticorps) expression did not directly mediate immune suppression, but the interaction between Tim3 (Montrer HAVCR2 Anticorps)+ T cells and monocytes, naive CD4 (Montrer CD4 Anticorps)+ T cells, and Gal9-expressing CD4 (Montrer CD4 Anticorps)+ CD25 (Montrer IL2RA Anticorps)+ Tregs could resulting in progressive suppression of Th1 (Montrer TH1L Anticorps) responses
The Tim-3 (Montrer HAVCR2 Anticorps)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
The relative abundance of PIBF (Montrer PIBF1 Anticorps), LGALS1 (Montrer LGALS1 Anticorps), LGALS3 (Montrer LGALS2 Anticorps), LGALS3BP (Montrer LGALS3BP Anticorps), and LGALS9 mRNA would display a differential expression pattern in the endometrium.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
lectin, galactoside-binding, soluble, 9
, galactoside-binding soluble lectin 9
, galectin 9
, lectin, galactoside-binding, soluble, 9 (galectin 9)
, lectin, galactose binding, soluble 5
, tumor antigen HOM-HD-21
, urate transporter/channel protein
, 36 kDa beta-galactoside-binding lectin
, Lectin galactose binding soluble 9 (Galectin-9)
, Lectin, galactose binding, soluble 9 (Galectin-9)
, urate transporter/channel
, urate transporter
, urate transporter/channel protein, isoform (UATp,i)