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anti-Nuclear Transcription Factor Y, alpha (NFYA) Anticorps

The protein encoded by NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. De plus, nous expédions NFYA Protéines (11) et NFYA Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NFYA 4800 P23511
NFYA 18044 P23708
NFYA 29508 P18576
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Top anti-NFYA Anticorps sur

Showing 10 out of 46 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Poulet Lapin Inconjugué IHC, WB WB Suggested Anti-NFYA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HepG2/293/COLO205 cells, using NFYA Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Humain Lapin Inconjugué IHC, WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Humain Lapin Inconjugué EMSA, EIA, IP, WB CHO-7 cells were cultured in the absence (1) or presence (2) of cholesterol. Equivalent aliquots of chromatin from each sample containing ~50 mg of total protein were analyzed by SDS-PAGE and immunoblot. After transfer, the membrane was probed using anti-NF-YA as the primary antibody at a 1:1000 dilution, followed by reaction with HRP conjugated Goat-anti-Rabbit IgG [H&L]. Signal was developed using an ECL kit followed by autoradiography using a 30", 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Boeuf (Vache) Lapin Inconjugué IC, IF, IP, IHC, WB Immunofluorescent analysis of NFYA staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of NFYA staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 7 to 8 Days
464,29 €
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
565,71 €
Chien Lapin Inconjugué IHC, ELISA, WB 100 μg Connectez-vous pour afficher 6 to 8 Days
374,52 €
Humain Lapin Inconjugué IHC, WB Western blot analysis of extract of various cells, using NFYA antibody. 100 μL Connectez-vous pour afficher 12 Days
261,90 €
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 15 to 21 Days
419,39 €

NFYA Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human , ,
Mouse (Murine)

Rat (Rattus)

anti-NFYA Anticorps mieux référencés

  1. Chicken Polyclonal NFYA Primary Antibody pour IHC, WB - ABIN2777267 : Zhu, Qian, Levy: CCAAT/enhancer-binding protein alpha (C/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y. dans The Journal of biological chemistry 2004 (PubMed)

  2. Human Polyclonal NFYA Primary Antibody pour ELISA, WB - ABIN1533666 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... dans Nature 2003 (PubMed)

Plus d’anticorps contre NFYA partenaires d’interaction

Human Nuclear Transcription Factor Y, alpha (NFYA) interaction partners

  1. Data indicate that specific cancer-driving nodes are generally under NF-YA/B control.

  2. our results indicate that NF-YA alternative splicing is an influential muscle cell determinant, through direct regulation of selected cell cycle blocking genes, and, directly and indirectly, of muscle-specific (Montrer EIF3K Anticorps) transcription factors

  3. enhanced CDCA8 (Montrer CDCA8 Anticorps) promoter activities by NF-Y overexpression and reduced CDCA8 (Montrer CDCA8 Anticorps) transcription by NF-Y knockdown further verified that NF-Y is a positive regulator of CDCA8 (Montrer CDCA8 Anticorps) transcription.

  4. Data show that Zinc-fingers and homeoboxes 2 (ZHX2 (Montrer ZHX2 Anticorps)) represses nuclear transcription factor Y alpha (NF-Y)-mediated activation of multidrug resistance 1 (MDR1 (Montrer TBC1D9 Anticorps)) transcription.

  5. NF-Y inhibits NT2/D1 cell growth in p53 (Montrer TP53 Anticorps)-independent manner and decreases SOX2 (Montrer SOX2 Anticorps) expression.

  6. Stimulation of the lymphocytes with phytohemagglutinin, restores normal OGG1 (Montrer OGG1 Anticorps) levels and repair rates. MAP kinase (Montrer MAPK1 Anticorps) c-Jun N-terminal kinase (JNK) and the recruitment of the transcription factor NFYA to the promoter region of OGG1 (Montrer OGG1 Anticorps) are shown to be involved.

  7. Association of p21 (Montrer CDKN1A Anticorps) with NF-YA suppresses the expression of PLK1 (Montrer PLK1 Anticorps) and prevents mitotic death in response to DNA damage.

  8. NF-YA binds directly over the CCAAT sequence.

  9. NF-Y recruits the developmentally regulated, erythroid transcription activator GATA-2 and general repressor BCL11A to modulate transcription of the gamma-globin gene.

  10. The crystal structure of NF-Y bound to a 25 bp CCAAT oligonucleotide shows that the histone-fold domains dimer binds to the DNA sugar-phosphate backbone, mimicking the nucleosome H2A/H2B-DNA assembly; NF-YA both binds to NF-YB (Montrer NFYB Anticorps)/NF-YC (Montrer NFYC Anticorps) and inserts an alpha helix deeply into the DNA minor groove, providing sequence-specific contacts to the CCAAT box.

Cow (Bovine) Nuclear Transcription Factor Y, alpha (NFYA) interaction partners

  1. Interaction of C/EBP-beta (Montrer CEBPB Anticorps) and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha (Montrer ACACA Anticorps) gene in cattle.

Mouse (Murine) Nuclear Transcription Factor Y, alpha (NFYA) interaction partners

  1. findings may point to a possible role of NF-YA in stress conditions that occur in chronic obesity, ER stress might be involved in the pathogenesis of obesity through NF-YA depletion.

  2. we conclude that NF-Y and YY1 (Montrer YY1 Anticorps) are important for the basal transcription of Pcyt2 (Montrer PCYT2 Anticorps) and that NF-Y is involved in the inhibitory effects of 25-HC on Pcyt2 (Montrer PCYT2 Anticorps) transcription.

  3. these results indicate that the transcription factor NF-Y regulates the proximal promoter activity of mouse Col11a1 (Montrer COL11A1 Anticorps) gene in chondrocytes

  4. these results raise an exciting possibility that targeting CDK1 (Montrer CDK1 Anticorps) or NF-Y in the diseased heart may inhibit fibrosis and subsequently confer cardioprotection.

  5. NF-Ya is a functional activator of Bmal1 (Montrer ARNTL Anticorps) transcription and it cooperates with Sp1 (Montrer SP1 Anticorps) and Rev-Erbalpha (Montrer NR1D1 Anticorps) to generate the daily cycle of Bmal1 (Montrer ARNTL Anticorps) expression.

  6. Sp1 (Montrer SP1 Anticorps), CREB (Montrer CREB1 Anticorps), HNF-1 (Montrer HNF1A Anticorps), and NF-Y, known to be responsive to hormones and diet, regulate NAGS (Montrer NAGS Anticorps) transcription

  7. results indicate nuclear transcription factor NF-Y as a pivotal upstream participant in a regulatory network necessary for the preservation of cycling hematopoietic stem cell.

  8. Findings establish that NF-Y acts upstream of E2F1 (Montrer E2F1 Anticorps) in p53 (Montrer TP53 Anticorps)-mediated apoptosis.

  9. Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y.

  10. NF-Y recruits RNAPII and general transcription factors onto various CCAAT box-containing promoters to permit strong transcriptional activation independently of histone modifications

NFYA profil antigène

Profil protéine

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Gene names and symbols associated with NFYA

  • nuclear transcription factor Y, alpha (nfya) anticorps
  • nuclear transcription factor Y, alpha (NFYA) anticorps
  • nuclear transcription factor-Y alpha (Nfya) anticorps
  • AA407810 anticorps
  • CBF-A anticorps
  • Cbf-b anticorps
  • HAP2 anticorps
  • ik:tdsubc_2b6 anticorps
  • NF-YA anticorps
  • NFYA anticorps
  • SEZ-10 anticorps
  • SEZ10 anticorps
  • wu:fb16e03 anticorps
  • xx:tdsubc_2b6 anticorps

Protein level used designations for NFYA

fb16e03 , tdsubc_2b6 , nuclear transcription factor Y, alpha , CAAT box DNA-binding protein subunit A , CAAT-box DNA binding protein subunit A , CCAAT-binding transcription factor subunit B , HAP2 CCAAT-binding protein , Transcription factor NF-Y, A subunit , nuclear transcription factor Y subunit A , nuclear transcription factor Y subunit alpha , CAAT-box DNA-binding protein subunit A , NF-Y protein chain A , nuclear transcription factor-Y alpha , NF-YA , CBF-B

83915 Danio rerio
748395 Pan troglodytes
4800 Homo sapiens
419917 Gallus gallus
474897 Canis lupus familiaris
539584 Bos taurus
18044 Mus musculus
29508 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-NFYA (NFYA) Anticorps
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