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anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Anticorps

The protein encoded by PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). De plus, nous expédions Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Protéines (14) et Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PPP1CA 19045 P62137
PPP1CA 5499 P62136
PPP1CA 24668 P62138
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Top anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Anticorps sur anticorps-enligne.fr

Showing 10 out of 126 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PPP1CA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-PPP1CA Antibody  Positive Control: Lane 1:441 µg HEK293 lysate Lane 2: 041 µg H1299 lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Goat anti-rabbit-HRP Secondry  Antibody Dilution: 1:0000Submitted by: Jose Luis Rosa, Universitat de Barcelona 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 0.1 mL Connectez-vous pour afficher 8 to 10 Days
341,00 €
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PP1-alpha (Phospho-Thr320) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using PP1-alpha (Ab-320) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PP1-alpha (Ab-320) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Souris Inconjugué IF, WB   0.1 mg Connectez-vous pour afficher 8 to 10 Days
374,00 €
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate. 100 μL Connectez-vous pour afficher 6 to 8 Days
399,32 €
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using PPP1CA mouse mAb against Hela (1), HepG2 (2), MCF-7 (3), Jurkat (4) and A549 (5) cell lysate. 100 μL Connectez-vous pour afficher 6 to 8 Days
494,23 €
Détails
Humain Souris Inconjugué ICC, WB PPP1CA antibody at 1/1000 dilution, Lane1: HepG2 whole cell lysate 40ug/Lane, Lane2: Hela whole cell lysate 40ug/Lane, Predicted band size:37kDa, Observed band size:37kDa PPP1CA (N-terminus) antibody at 1/2000 dilution, Lane1: HepG2 whole cell lysate 40ug/Lane, Lane2: Hela whole cell lysate 40ug/Lane, Predicted band size: 37kDa, Observed band size: 37kDa 100 μL Connectez-vous pour afficher 6 to 8 Days
374,15 €
Détails
Humain Souris Inconjugué ICC, IHC, WB All lanes: PPP1CA antibody at 1/1000 dilution, Lane1: MCF7 Whole cell lysate 30ug/lane, Lane2: K562 Whole cell lysate 30ug/lane, Lane3: Hela Whole cell lysate 30ug/lane, Lane4: HEPG2 Whole cell lysate 30ug/lane, Lane5: Jurkat Whole cell lysate 30ug/lane, Predicted band size: 38kDa, Observed band size: 38kDa IHC of paraffin-embedded human breast cancer using anti- PPP1CA diluted 1/500-1/1000. 100 μL Connectez-vous pour afficher 6 to 8 Days
374,15 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using PPP1A, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2500. WB Image Sample(30 μg of whole cell lysate) A:293T B:A431, 12% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails

PPP1CA Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Anticorps mieux référencés

  1. Human Monoclonal PPP1CA Primary Antibody pour ELISA, WB - ABIN969360 : Chen, Kesler, Paschal, Balk: Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. dans The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN969360

  2. Human Monoclonal PPP1CA Primary Antibody pour ELISA, WB - ABIN969359 : Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. dans The EMBO journal 2007 (PubMed)
    Show all 2 references for ABIN969359

  3. Human Monoclonal PPP1CA Primary Antibody pour IF, WB - ABIN1108708 : Barker, Jones, da Cruz e Silva, Spurr, Sheer, Cohen: Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13. dans Genomics 1990 (PubMed)
    Show all 2 references for ABIN1108708

  4. Human Monoclonal PPP1CA Primary Antibody pour EIA, IHC (p) - ABIN238369 : Cohen: Protein phosphatase 1--targeted in many directions. dans Journal of cell science 2002 (PubMed)
    Show all 2 references for ABIN238369

  5. Cow (Bovine) Polyclonal PPP1CA Primary Antibody pour WB - ABIN2787782 : Lesage, Beullens, Pedelini, Garcia-Gimeno, Waelkens, Sanz, Bollen: A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3. dans Biochemistry 2007 (PubMed)

  6. Human Polyclonal PPP1CA Primary Antibody pour IHC, ELISA - ABIN1532484 : Song, Khanna, Lu, Lavin: Cloning and characterization of a human protein phosphatase 1-encoding cDNA. dans Gene 1993 (PubMed)

Plus d’anticorps contre Protein Phosphatase 1, Catalytic Subunit, alpha Isoform partenaires d’interaction

Mouse (Murine) Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) interaction partners

  1. findings demonstrate a novel regulatory circuit in which STING and TBK1 (Montrer TBK1 Anticorps) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (Montrer PPM1A Anticorps) dephosphorylates STING and TBK1 (Montrer TBK1 Anticorps)

  2. the studies presented here position PPM1A (Montrer PPM1A Anticorps) as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions

  3. Ang (Montrer ANG Anticorps) IV functions via regulating the activity of PP1 (Montrer PPP1CC Anticorps)

  4. a nuclear envelope-localized mechanism of inactivating TGF-beta (Montrer TGFB1 Anticorps) signaling in which MAN1 (Montrer LEMD3 Anticorps) competes with transcription factors for binding to Smad2 (Montrer SMAD2 Anticorps) and Smad3 (Montrer SMAD3 Anticorps) and facilitates their dephosphorylation by PPM1A (Montrer PPM1A Anticorps).

  5. Although a non-myristoylated mutation (G2A (Montrer GPR132 Anticorps)) of PPM1A (Montrer PPM1A Anticorps) and PPM1B (Montrer PPM1B Anticorps) prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha (Montrer GRK4 Anticorps).

  6. we found that PPM1A (Montrer PPM1A Anticorps) mRNA is synthesized at the beginning of the maturation process and remains elevated in the mature oocytes, promoting the accumulation of PPM1A (Montrer PPM1A Anticorps) protein

  7. Cell surface expression of the major amyloid-beta peptide (Abeta (Montrer APP Anticorps))-degrading enzyme, neprilysin (Montrer MME Anticorps), depends on phosphorylation by mitogen-activated protein kinase (Montrer MAPK1 Anticorps)/extracellular signal-regulated kinase kinase (MEK (Montrer MDK Anticorps)) and dephosphorylation by protein phosphatase 1a (Montrer PPM1A Anticorps).

  8. analysis of selective regulation of NR2B (Montrer GRIN2B Anticorps) by protein phosphatase-1 (Montrer PPP1CB Anticorps) for the control of the NMDA receptor in neuroprotection

  9. Protein phosphatase PPM1A (Montrer PPM1A Anticorps) regulates the nuclear export of Smad2 (Montrer SMAD2 Anticorps)/3 through targeting nuclear exporter RanBP3 (Montrer RANBP3 Anticorps).

  10. Ppm1a (Montrer PPM1A Anticorps), through suppressing Smad2 (Montrer SMAD2 Anticorps) signaling, plays a critical role in re-epithelialization during wound healing

Human Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) interaction partners

  1. These results indicate that PP1 (Montrer PPA1 Anticorps) is recruited to the extracellular calcium-dependent E-cadherin (Montrer CDH1 Anticorps)-catenin-PIP5K1a (Montrer PIP5K1A Anticorps) complex in the plasma membrane to activate PIP5K1a (Montrer PIP5K1A Anticorps), which is required for PLC (Montrer HSPG2 Anticorps)-g1 activation leading to keratinocyte differentiation.

  2. Data suggest that targeting protein phosphatase 1 catalytic subunit (Montrer PPP1CB Anticorps) (PP1alpha) or the androgen receptor AR (Montrer AR Anticorps)-PP1alpha interaction may be effective in castration-resistant prostate cancer (CRPC).

  3. Both PP-1 (Montrer PPA1 Anticorps) and PP-2A are directly involved in regulating eye development, and are aberrantly expressed in cataract and glaucoma patients. (Review)

  4. Data suggest that activation of TAZ (tafazzin (Montrer TAZ Anticorps)) inhibits adipogenesis in mesenchymal stem cells; interaction of TAZ (Montrer TAZ Anticorps) and protein phosphatases (PP1A, PP2A (Montrer PPP2R4 Anticorps)) up-regulates dephosphorylation and transport of TAZ (Montrer TAZ Anticorps) to cell nucleus.

  5. ATG16L1 (Montrer ATG16L1 Anticorps) as a bona fide physiological CSNK2 and PPP1 substrate, which reveals a novel molecular link from CSNK2 to activation of the autophagy-specific ATG12 (Montrer ATG12 Anticorps)-ATG5 (Montrer ATG5 Anticorps)-ATG16L1 (Montrer ATG16L1 Anticorps) complex and autophagy induction

  6. PARD3 (Montrer PARD3 Anticorps) promotes interaction between PP1A and LATS1 (Montrer LATS1 Anticorps) to induce LATS1 (Montrer LATS1 Anticorps) dephosphorylation and inactivation,leading to dephosphorylation and activation of TAZ (Montrer TAZ Anticorps)

  7. activation of the Nherf1 (Montrer SLC9A3R1 Anticorps)-PP1alpha-TAZ (Montrer TAZ Anticorps) pathway in osteoblasts is targeted by histone deacetylase (Montrer HDAC1 Anticorps) inhibitors

  8. findings demonstrate a novel regulatory circuit in which STING and TBK1 (Montrer TBK1 Anticorps) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (Montrer PPM1A Anticorps) dephosphorylates STING and TBK1 (Montrer TBK1 Anticorps)

  9. Protein phosphatase 1 (Montrer PPP1CB Anticorps) (PP1 (Montrer PPA1 Anticorps)) activity is critical for radiosensitization in non-small cell lung cancer cells and PP1 (Montrer PPA1 Anticorps) activators can serve as promising radiosensitizers to improve therapeutic efficacy.

  10. The TGF-beta (Montrer TGFB1 Anticorps)/Smad (Montrer SMAD1 Anticorps) signaling system decreases its activity through strong negative regulation. We provide evidence for a new negative feedback loop through PPM1A (Montrer PPM1A Anticorps) upregulation.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) profil antigène

Profil protéine

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene names and symbols associated with PPP1CA

  • protein phosphatase 1, catalytic subunit, alpha isozyme (ppp1ca) anticorps
  • protein phosphatase 1, catalytic subunit, alpha isozyme (PPP1CA) anticorps
  • protein phosphatase 1, catalytic subunit, alpha isoform (Ppp1ca) anticorps
  • protein phosphatase 1, catalytic subunit, alpha isoform a (ppp1caa) anticorps
  • protein phosphatase 1, catalytic subunit, alpha isozyme (Ppp1ca) anticorps
  • protein phosphatase 1, catalytic subunit, beta isozyme (Ppp1cb) anticorps
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) anticorps
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (PPM1A) anticorps
  • 2310003C21Rik anticorps
  • 2900017D14Rik anticorps
  • AI427932 anticorps
  • AU017636 anticorps
  • dism2 anticorps
  • MMPa-2 anticorps
  • MPPa-1 anticorps
  • PP-1A anticorps
  • PP1A anticorps
  • PP1alpha anticorps
  • PP2C-ALPHA anticorps
  • PP2CA anticorps
  • PP2Calpha anticorps
  • PPP1A anticorps
  • Ppp1c anticorps
  • wu:fc04c08 anticorps
  • wu:fc09b07 anticorps
  • wu:fc30g11 anticorps
  • wu:fe05h08 anticorps
  • zgc:85729 anticorps

Protein level used designations for PPP1CA

Protein phosphatase type 1 alpha, catalytic subunit , protein phosphatase 1, catalytic subunit, alpha isoform , PP-1A , serine/threonine-protein phosphatase PP1-alpha catalytic subunit , ppp1ca , protein phosphatase 1, catalytic subunit, alpha , serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit , protein phosphatase-1d , PP-1B , protein phosphatase 1, catalytic subunit, beta isoform , protein phosphatase-1a , serine/threonine-protein phosphatase PP1-beta catalytic subunit , Mpp alpha , PP2C-alpha , protein phosphatase 1A , protein phosphatase 2C isoform alpha , protein phosphatase IA , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , IA , protein phosphatase 2C alpha

GENE ID SPECIES
379914 Xenopus laevis
745709 Pan troglodytes
100059233 Equus caballus
100145598 Xenopus (Silurana) tropicalis
19045 Mus musculus
407980 Danio rerio
5499 Homo sapiens
24668 Rattus norvegicus
516175 Bos taurus
403609 Canis lupus familiaris
100009298 Oryctolagus cuniculus
25594 Rattus norvegicus
19042 Mus musculus
5494 Homo sapiens
281994 Bos taurus
100009431 Oryctolagus cuniculus
Fournisseurs de qualité sélectionnés pour anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Anticorps
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