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SOX15 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. De plus, nous expédions SOX15 Anticorps (50) et SOX15 Protéines (3) et beaucoup plus de produits pour cette protéine.
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Increased expression of epithelial OCT4 (Montrer POU5F1 Kits ELISA), SOX15 and TWIST1 (Montrer TWIST1 Kits ELISA) was detected in endometriotic tissue compared to endometriosis patient endometrium. Epithelial expression of OCT4 (Montrer POU5F1 Kits ELISA), SOX15, and TWIST1 (Montrer TWIST1 Kits ELISA) was increased in the endometrium of endometriosis patients compared to controls.
Results indicate that the expression of SOX15 in pancreatic cancer cell lines with undetectable expression resulted in reduced viability of cancer cells both in vitro and in vivo demonstrating its tumor suppressive capability.
We established stable NT2/D1 cell lines overexpressing SOX15 (SOX15-NT2/D1), and a modified 3-(4,5-dime-thylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that the SOX15-NT2/D1 cells exhibited significantly slower growth than controls
The gain of function studies indicated that sex-determining region Y (SRY (Montrer SRY Kits ELISA))-box 15 (SOX15) activate NR5A1 (Montrer NR5A1 Kits ELISA) gene expression.
Sox15 and Sox2 (Montrer SOX2 Kits ELISA) have distinct roles in transcriptional control in mouse ES cells
role in increasing Hand1 (Montrer HAND1 Kits ELISA) transcriptional activity might promote the transcription of the target gene resulting in the trophoblast giant cell differentiation in the mouse placenta
These studies demonstrate that Sox15, Fhl3 (Montrer FHL3 Kits ELISA) and Foxk1 (Montrer Foxk1 Kits ELISA) function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration.
These results suggest that the region from -297 to -8 of the Sox15 gene contains three distinct cis (Montrer CISH Kits ELISA)-elements, and that these sequences were conserved among eutherian mammals during vertebrate evolution.
both Sox7 (Montrer SOX7 Kits ELISA) and Sox15 are able to induce the early stages of myogenesis, but only Sox7 (Montrer SOX7 Kits ELISA) is sufficient to initiate the formation of fully differentiated skeletal myocytes.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
SRY (sex determining region Y)-box 20
, protein SOX-15
, SRY-box containing gene 15