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anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Anticorps

SREBF2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. De plus, nous expédions Sterol Regulatory Element Binding Transcription Factor 2 Protéines (10) et Sterol Regulatory Element Binding Transcription Factor 2 Kits (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SREBF2 20788 Q3U1N2
SREBF2 6721 Q12772
SREBF2 300095 Q3T1I5
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Top anti-Sterol Regulatory Element Binding Transcription Factor 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 65 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IF, IHC (p), WB Confocal immunofluorescent analysis of SREBF2 Antibody (Center) (ABIN654630) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Poulet Lapin Inconjugué WB <b>WB Suggested Anti-SREBF2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Raji cell lysate WB Suggested Anti-SREBF2 Antibody <br /> Positive Control: Lane 1:541 µg mouse glomerular endothelial lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP Secondry <br /> Antibody Dilution: 1:0000<br />Submitted by: Xiaoxin Wang, UC Denver 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, IF, IHC (p), WB Confocal immunofluorescent analysis with HepG2 cells using SREBF2 / SREBP2  Antibody , followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Immunohistochemistry analysis in human skin carcinoma, followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SREBF2 antibody for IHC; Clinical relevance has not been evaluated. 0.4 mL Connectez-vous pour afficher 8 to 10 Days
418,00 €
Détails
Humain Souris Inconjugué IP, WB Western blot analysis of SREBP-2. Jurkat (ATCC TIB-152) cells were left untreated (lanes 1 & 2) or treated with 1 µM Staurosporin for 4 hours (lanes 3 & 4) to induce apoptosis. Cell lysates were probed with Purified Mouse Anti-SREBP-2 (ABIN967564). As apoptosis is induced, the SREBP-2 125 kDa precursor is cleaved to its ~70 kDa size. 0.1 mg Connectez-vous pour afficher 2 to 4 Days
225,15 €
Détails
Humain Lapin Inconjugué ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using SREBF2, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: HeLa 7.5% SDS PAGE antibody diluted at 1:500 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Souris Inconjugué ChIP, WB   100 μg Connectez-vous pour afficher 1 to 3 Days
486,11 €
Détails
Poulet Lapin Inconjugué WB <b>WB Suggested Anti-SREBF2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:7812500<br><b>Positive Control: </b>Transfected 293T 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué WB SREBF2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the SREBP2 antibody detected the SREBP2 protein (arrow). SREBP2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SREBP2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 100 μL Connectez-vous pour afficher 6 to 8 Days
360,85 €
Détails
Humain Lapin Inconjugué IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
801,43 €
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails

SREBF2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Mouse (Murine) , , , ,

Human , , , ,
, ,
Rat (Rattus) , , , ,

anti-Sterol Regulatory Element Binding Transcription Factor 2 Anticorps mieux référencés

  1. Human Polyclonal SREBF2 Primary Antibody pour EIA, WB - ABIN499111 : Hua, Yokoyama, Wu, Briggs, Brown, Goldstein, Wang: SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. dans Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 6 references for ABIN499111

  2. Human Polyclonal SREBF2 Primary Antibody pour EIA, IF - ABIN954950 : Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN954950

  3. Human Monoclonal SREBF2 Primary Antibody pour IP, WB - ABIN967564 : Hua, Sakai, Ho, Goldstein, Brown: Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN967564

  4. Human Polyclonal SREBF2 Primary Antibody pour IF, IHC (p) - ABIN654630 : Marquart, Allen, Ory, Baldán: miR-33 links SREBP-2 induction to repression of sterol transporters. dans Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN654630

  5. Chicken Polyclonal SREBF2 Primary Antibody pour WB - ABIN2792226 : Zeng, Liao, Liu, Lee, Zhu, Wang, Stemerman, Zhu, Shyy: Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. dans The Journal of biological chemistry 2004 (PubMed)

  6. Human Monoclonal SREBF2 Primary Antibody pour ChIP, WB - ABIN2668815 : Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment. dans PLoS ONE 2014 (PubMed)

Plus d’anticorps contre Sterol Regulatory Element Binding Transcription Factor 2 partenaires d’interaction

Mouse (Murine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. activation of the sterol regulatory element binding protein-2 (SREBP2) was found to be downstream of ER stress, and this activation was affirmed to account for the intracellular accumulation of cholesterol using RNAi technique

  2. ITCH modulates SIRT6 (Montrer SIRT6 Anticorps) and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE (Montrer APOE Anticorps) null mice

  3. SREBP2-induced miR-92a targets k (Montrer MLXIP Anticorps)ey molecules in endothelial homeostasis, including sirtuin 1, Kruppel-like factor 2, and Kruppel-like factor 4, leading to NOD-like receptor family pyrin domain-containing 3 inflammasome activation and endothelial nitric oxide synthase inhibition.

  4. The cholesterol-lowering effects of FGF21 (Montrer FGF21 Anticorps) are abrogated by hepatic expression of sterol regulatory element-binding protein-2.

  5. Data indicate that Leishmania exploits macrophage cholesterol-dependent sterol regulatory element binding factor 2 (SREBP2) circuit to facilitate its entry and survival within the host.

  6. Demonstrate that the activation of FXR (Montrer NR1H4 Anticorps) uncouples the expression of nuclear SREBP-2 and miR (Montrer MLXIP Anticorps)-33, and the regulation of their respective target genes.

  7. the cardiac sterol regulatory element-binding protein-2/3-hydroxy-3-methylglutaryl-coenzyme A reductase (Montrer HMGCR Anticorps) pathway being upregulated in MMP-2 (Montrer MMP2 Anticorps) deficiency.

  8. activation of intestinal SREBP2 alone seems to be sufficient to increase plasma cholesterol

  9. Hepatic insulin receptor (Montrer INSR Anticorps) knockout mice manifest decreased nuclear SREBP-2 protein, decreased cholesterologenic gene expression, and decreased cholesterol synthesis.

  10. The regulation of SREBP-2 in cholesterol transport is through activation of NF-kappaB (Montrer NFKB1 Anticorps).

Human Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. Data suggest lysophosphatidylcholine (LPC (Montrer PCSK7 Anticorps)) up-regulates SREBP-2 and cholesterol efflux in vascular endothelium; 25-hydroxycholesterol (25-HC) inhibits these effects of LPC (Montrer PCSK7 Anticorps); both LPC (Montrer PCSK7 Anticorps) and 25-HC up-regulate release of interleukin-6 (Montrer IL6 Anticorps) and interleukin-8 (Montrer IL8 Anticorps).

  2. the results of the present study showed that luteolin modulates HMGCR (Montrer HMGCR Anticorps) transcription by decreasing the expression and nuclear translocation of SREBP-2.

  3. performed a detailed promoter/enhancer analysis of ELOVL5 (Montrer ELOVL5 Anticorps) gene, and identified two new SREBP binding sites, one in the 10 kb upstream region and one in the exon 1

  4. HCV core protein disturbs the cholesterol homeostasis in HepG2 cells via the SREBP2 pathway; miR-185-5p is involved in the regulation of SREBP2 by the core protein.

  5. the 5-aminoimidazole-4-carboxyamide ribonucleoside (AICAR (Montrer ATIC Anticorps))-induced activation of AMPK (Montrer PRKAA1 Anticorps) directly inhibited the expression of SREBP-2 and HMGCR (Montrer HMGCR Anticorps) and HMGCS (Montrer HMGCS1 Anticorps), and suppressed the TSH-stimulated up-regulation of SREBP-2 in HepG2 cells.

  6. Methyl protodioscin increases ABCA1 (Montrer ABCA1 Anticorps) expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels.

  7. Suggest important role for SREBP-2 in regulation of lipid and glucose metabolism in hypertensive rats.

  8. Our results show that though leptin (Montrer LEP Anticorps) stimulates LDLR (Montrer LDLR Anticorps) expression very weakly through JAK (Montrer JAK3 Anticorps)-STAT (Montrer STAT1 Anticorps) signaling pathway, it mainly imposes inhibition on LDLR (Montrer LDLR Anticorps) expression by inhibiting transcription factor SREBP2

  9. The results of this study suggested that the genetic polymorphisms of SREBF2 gene may be associated with metabolic syndrome in patients treated with clozapine.

  10. SREBP-2 rs2228314 G to C change and variant C genotype as well as LXRalpha rs11039155 G to A change and variant A may contribute to PCOS in Chinese Han population

Pig (Porcine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. dysregulation of SIRT1 (Montrer SIRT1 Anticorps)-AMPK (Montrer PRKAA1 Anticorps)-SREBP and stimulation of NLRP3 (Montrer NLRP3 Anticorps) inflammasome may contribute to vascular lipid deposition and inflammation in atherosclerosis

  2. KLF13 (Montrer KLF13 Anticorps) and SREBP-Sp1 (Montrer SP1 Anticorps) activation interact to regulate low density lipoprotein receptor (Montrer LDLR Anticorps) promoter function

Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) profil antigène

Profil protéine

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Gene names and symbols associated with SREBF2

  • sterol regulatory element binding transcription factor 2 (SREBF2) anticorps
  • sterol regulatory element binding transcription factor 2 (srebf2) anticorps
  • sterol regulatory element binding protein 2 (SREBP2) anticorps
  • sterol regulatory element binding factor 2 (Srebf2) anticorps
  • sterol regulatory element binding protein-2 (SREBP-2) anticorps
  • sterol regulatory element binding transcription factor 2 (Srebf2) anticorps
  • AI608257 anticorps
  • bHLHd2 anticorps
  • lop13 anticorps
  • nuc anticorps
  • SREBF2 anticorps
  • Srebf2_retired anticorps
  • SREBP-2 anticorps
  • SREBP2 anticorps
  • SREBP2gc anticorps
  • zgc:158371 anticorps

Protein level used designations for SREBF2

sterol regulatory element binding transcription factor 2 , sterol regulatory element-binding protein 2-like , sterol regulatory element binding protein 2 , SREBP-2 , sterol regulatory element-binding protein 2 , sterol regulatory element-binding transcription factor 2 , class D basic helix-loop-helix protein 2 , sterol regulatory element binding factor 2

GENE ID SPECIES
712307 Macaca mulatta
100070704 Equus caballus
100144677 Xenopus (Silurana) tropicalis
100480211 Ailuropoda melanoleuca
100552463 Anolis carolinensis
100124292 Monodelphis domestica
507102 Bos taurus
100037309 Danio rerio
100502557 Salmo salar
20788 Mus musculus
100008783 Oryctolagus cuniculus
443980 Xenopus laevis
395304 Gallus gallus
6721 Homo sapiens
481228 Canis lupus familiaris
396675 Sus scrofa
300095 Rattus norvegicus
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