anti-Transcription Factor 12 (TCF12) Anticorps

The protein encoded by TCF12 is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. De plus, nous expédions TCF12 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TCF12 6938 Q99081
TCF12 21406 Q61286
TCF12 25720 P51514
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Top anti-TCF12 Anticorps sur anticorps-enligne.fr

Showing 10 out of 92 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TCF12 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-TCF12 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Jurkat cell lysate <br /> TCF12 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TCF12 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Hela cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TCF12 Antibody Titration: </b>0.06ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human Lung Host: Rabbit <br /> Target Name: TCF12 <br /> Sample Tissue: Human Fetal Brain <br /> Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: TCF4 Sample Tissue: Human Uterus Tumor Antibody Dilution: 1ug/ml 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, WB TCF12 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TCF12 antibody detected the TCF12 protein (arrow). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Poulet Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to TCF12 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of TCF12 expression in transfected 293T cell line by TCF12 monoclonal antibody (M01), clone 2E9. Lane 1: TCF12 transfected lysate(75.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails

TCF12 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-TCF12 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal TCF12 Primary Antibody pour WB - ABIN2780487 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. dans Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre TCF12 partenaires d’interaction

Human Transcription Factor 12 (TCF12) interaction partners

  1. Heb expression is regulated by Med19 (Montrer MED19 Anticorps) in breast cancer cells.

  2. enforced expression of transcription factor 12 suppressed cell proliferation, migration, and invasion in vitro and inhibited tumor growth in vivo. In conclusion, transcription factor 12 protein may be a novel molecule which plays a critical role in prostate cancer progression and patients' prognosis, suggesting it might be a promising therapeutic target for prostate cancer therapy

  3. HEB may be involved in GBM cell proliferation, as HEB silencing reduced proliferation in cells cultured as monolayers or neurospheres. Furthermore, the results suggested a potential role for HEB in the maintenance of GBM stem cells, as HEB silencing affected the differentiation capacity of cells.

  4. Two novel translocations leading to the inactivation of RUNX1 (Montrer RUNX1 Anticorps) and its partners SIN3A (Montrer SIN3A Anticorps) and TCF12 in myeloid leukemia (Montrer BCL11A Anticorps).

  5. Studies suggest that transcription factor 12 (TCF12) should be included in level 2 genetic testing.

  6. show that these mutations compromise TCF12 transcriptional activity and are associated with a more aggressive tumour type

  7. several familial cases of coronal synostosis associated with mutations in TCF12

  8. In t(8;21) leukemia cells, the two E proteins, HEB and E2A (Montrer TCF3 Anticorps), function as components of the stable AML1 (Montrer RUNX1 Anticorps)-ETO (Montrer RUNX1T1 Anticorps)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  9. haploinsufficiency of TCF12 causes coronal synostosis in humans and that severe bilateral coronal synostosis occ (Montrer TWIST1 Anticorps)urs in mice with 50% of the wild-type dosage of both the T (Montrer TWIST1 Anticorps)cf12 and Twist1 genes highlights the key role of TCF12 acting with TWIST1.

  10. the CD91 (Montrer LRP1 Anticorps)/IKK (Montrer CHUK Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signaling cascade is involved in secreted HSP90alpha (Montrer HSP90AA2 Anticorps)-induced TCF12 expression, leading to E-cadherin (Montrer CDH1 Anticorps) down-regulation and enhanced CRC (Montrer CALR Anticorps) cell migration/invasion

Mouse (Murine) Transcription Factor 12 (TCF12) interaction partners

  1. we identified transcription factor TCF12 as a new target of miR (Montrer MLXIP Anticorps)-211 in oral squamous cell carcinoma

  2. HEB (Montrer FREM1 Anticorps) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  3. severe bilateral coronal synostosis occurs in mice with 50% of the wild-type dosage of both the Tcf12 and Twist1 (Montrer TWIST1 Anticorps) genes highlights the key role of TCF12 acting with TWIST1 (Montrer TWIST1 Anticorps) in the normal development of the coronal sutures

  4. Deficiency in the E proteins, E2A (Montrer TCF3 Anticorps) and HEB (Montrer FREM1 Anticorps), led to increased frequency of terminally differentiated effector KLRG1 (Montrer KLRG1 Anticorps)(hi) CD8 (Montrer CD8A Anticorps)(+) T cells in mice during infection, and decreased generation of longer-lived memory-precursor cells during the immune response.

  5. Deletion of HEB (Montrer FREM1 Anticorps) and E2A (Montrer TCF3 Anticorps) in DP thymocytes specifically blocked the development of CD4 (Montrer CD4 Anticorps)(+) lineage T cells. Furthermore, deletion of the E protein inhibitors Id2 and Id3 (Montrer ID3 Anticorps) allowed CD4 (Montrer CD4 Anticorps)(+) T cell development but blocked CD8 (Montrer CD8A Anticorps)(+) lineage development.

  6. the earliest event in B-cell specification involves the induction of FOXO1 (Montrer FOXO1 Anticorps) expression and requires the combined activities of E2A (Montrer TCF3 Anticorps) and HEB (Montrer FREM1 Anticorps)

  7. These results showed a new set of interactions between HEB (Montrer FREM1 Anticorps), Notch1 (Montrer NOTCH1 Anticorps), and GATA3 (Montrer GATA3 Anticorps) that regulate the T-cell fate choice in developing thymocytes.

  8. Developmental progression of fetal HEB (Montrer FREM1 Anticorps)(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.

  9. HEB (Montrer FREM1 Anticorps) is a specific and essential factor in T-cell development and in the generation of the iNKT cell lineage.

  10. the dosage of HEB (Montrer FREM1 Anticorps) determines pT alpha (Montrer PTCRA Anticorps) gene expression in immature T cells

TCF12 profil antigène

Profil protéine

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with TCF12

  • transcription factor 12 (TCF12) anticorps
  • transcription factor 12 (LOC100339415) anticorps
  • transcription factor 12 (tcf12) anticorps
  • transcription factor 12 (Tcf12) anticorps
  • transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) (tcf12) anticorps
  • A130037E08Rik anticorps
  • ALF1 anticorps
  • bHLHb20 anticorps
  • CRS3 anticorps
  • HEB anticorps
  • HEBAlt anticorps
  • HsT17266 anticorps
  • HTF-4 anticorps
  • HTF4 anticorps
  • ME1 anticorps
  • REB anticorps
  • SCBPA anticorps
  • TCF12 anticorps
  • wu:fb74g05 anticorps
  • wu:fc43e06 anticorps
  • zgc:85956 anticorps
  • zgc:110341 anticorps

Protein level used designations for TCF12

transcription factor 12 , transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) , DNA-binding protein HTF4 , E-box-binding protein , TCF-12 , class B basic helix-loop-helix protein 20 , helix-loop-helix transcription factor 4 , transcription factor HTF-4 , class A helix-loop-helix transcription factor ME1 , SCBP alpha , SCBP-alpha , salivary-specific cAMP response element-binding protein alpha , TF12 , basic helix-loop-helix protein , class A helix-loop-helix transcription factor GE1 , XE1.1

GENE ID SPECIES
453466 Pan troglodytes
100339415 Oryctolagus cuniculus
100460448 Pongo abelii
100553875 Anolis carolinensis
100603993 Nomascus leucogenys
6938 Homo sapiens
509039 Bos taurus
21406 Mus musculus
25720 Rattus norvegicus
407985 Danio rerio
396334 Gallus gallus
100684199 Canis lupus familiaris
399451 Xenopus laevis
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