POMC anticorps

N° du produit ABIN1105257

Détail du produit anti-POMC anticorps

Antigène: POMC (Proopiomelanocortin (POMC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp POMC est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Specific for Synacthen (1-24 ACTH). Reacts with ACTH (a.a. 1-17) and does not cross-react with CLIP (ACTH 17-39). It cross-reacts with Rat N-terminal ACTH.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Keyhole Limpet Haemocyanin conjugated Human ACTH (1-17)

Clone: 57

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) -20 °C for longer.

Détails sur POMC

Antigène: POMC (Proopiomelanocortin (POMC))

Autre désignation: POMC (POMC Produits)

Synonymes: anticorps MSH, anticorps ACTH, anticorps pomc, anticorps SI:bZ36D5.1, anticorps SI:bZ36D5.4, anticorps si:bz36d5.2, anticorps BE, anticorps Beta-LPH, anticorps Clip, anticorps Gamma-LPH, anticorps Npp, anticorps Pomc-1, anticorps Pomc1, anticorps alpha-MSH, anticorps alphaMSH, anticorps beta-MSH, anticorps gamma-MSH, anticorps CLIP, anticorps LPH, anticorps NPP, anticorps POC, anticorps Pomc2, anticorps proopiomelanocortin a, anticorps pro-opiomelanocortin-alpha, anticorps proopiomelanocortin, anticorps pomca, anticorps Pomc, anticorps POMC

Sujet: ACTH (Synacthen) which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC

ID gène: 5443

NCBI Accession: NP_000930

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour