Cytochrome C anticorps
Aperçu rapide pour Cytochrome C anticorps (ABIN126969)
Antigène
Voir toutes Cytochrome C (CYCS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Séquence
- surroundin g amino acid 70
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Specificité
- The cytochrome c antibody detects the 12.6 kDa cytochrome c.
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Purification
- Protein A purified
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Immunogène
- Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c.
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Indications d'application
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Western Blot: 0.5-4 μg/mL, Jurkat cell lysate, NIH3T3 cell lysate, and rat kidney tissue lysatecan be used as positive controls. Immunoprecipitation: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Autre désignation
- Cytochrome C
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Sujet
- Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.Synonyms: CYC, CYCS
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ID gène
- 54205
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NCBI Accession
- NP_061820
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UniProt
- P99999
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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