DYRK2 anticorps (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2) (HRP)

Details for Product anti-DYRK2 Antibody No. ABIN1712248, Fournisseur: Connectez-vous pour afficher
Antigène
  • DYRK2
  • fc18c09
  • si:ch211-266a5.8
  • wu:fa09g03
  • wu:fc18c09
  • 1810038L18Rik
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
  • dual specificity tyrosine-phosphorylation-regulated kinase 2
  • DYRK2
  • CpipJ_CPIJ014802
  • dyrk2
  • Dyrk2
Reactivité
Humain, Souris, Rat (Rattus)
93
33
23
4
4
4
4
4
4
3
2
1
1
1
Hôte
Lapin
83
16
1
Clonalité
Polyclonal
Conjugué
Cet anticorp DYRK2 est conjugé à/à la HRP
7
6
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
49
41
14
13
13
9
3
2
2
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human DYRK2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Dyrk2 (DYRK2 Antibody Extrait)
Sujet

Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (1â€"3). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).

Synonyms: 1810038L18Rik, Dual specicity tyrosine Y phosphorylation regulated kinase 2, Dual specicity tyrosine phosphorylation regulated kinase 2, Dual specicity tyrosine-phosphorylation-regulated kinase 2, DYRK2, DYRK2_HUMAN, EC 2.7.12.1, FLJ21217, FLJ21365.

ID gène 8445
Domaine de recherche Signaling, Tyrosine Kinases
Pathways Regulation of Carbohydrate Metabolic Process
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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