SIRT3 anticorps (C-Term)
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- Antigène Voir toutes SIRT3 Anticorps
- SIRT3 (Sirtuin 3 (SIRT3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIRT3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- VGPLAWHPRS RDVAQLGDVV HGVESLVELL GWTEEMRDLV QRETGKLDGP
- Homologie
- Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT3
- Top Product
- Discover our top product SIRT3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 257 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." dans: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).
: "Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27313, (2011) (PubMed).
: "Endurance exercise as a countermeasure for aging." dans: Diabetes, Vol. 57, Issue 11, pp. 2933-42, (2008) (PubMed).
: "
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Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." dans: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).
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- Antigène
- SIRT3 (Sirtuin 3 (SIRT3))
- Autre désignation
- SIRT3 (SIRT3 Produits)
- Synonymes
- anticorps zgc:158774, anticorps sirtuin, anticorps SIR2L3, anticorps 2310003L23Rik, anticorps AI848213, anticorps Sir2l3, anticorps sirtuin 3, anticorps sirt3, anticorps SIRT3, anticorps Sirt3
- Sujet
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The SIRT3 gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 encodes a protein that is included in class I of the sirtuin family.
Alias Symbols: SIR2L3
Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
Protein Size: 257 - Poids moléculaire
- 28 kDa
- ID gène
- 23410
- NCBI Accession
- NM_001017524, NP_001017524
- UniProt
- Q9NTG7
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