CACNA1B anticorps

N° du produit ABIN265031

Détail du produit anti-CACNA1B anticorps

Antigène: CACNA1B (Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1B est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to CACNA1B.

Purification: Purified

Immunogène: Synthetic peptide derived from the rat alpha1B calcium channel conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur CACNA1B

Antigène: CACNA1B (Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B))

Autre désignation: CACNA1B (CACNA1B Produits)

Synonymes: anticorps BIII, anticorps CACNL1A5, anticorps CACNN, anticorps Cav2.2, anticorps AW050276, anticorps AW060892, anticorps AW822256, anticorps Cchn1a, anticorps alpha(1B), anticorps calcium voltage-gated channel subunit alpha1 B, anticorps calcium channel, voltage-dependent, N type, alpha 1B subunit, anticorps CACNA1B, anticorps Cacna1b

Sujet: Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1b gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by omega-conotoxin-GVIA (omega-ctx-GVIA) and by omegaagatoxin-IIIA (omega-aga-IIIA). They are however insensitive to dihydropyridines (dhp), and omega-agatoxin-IVA (omegaaga-IVA). Calcium channels containing alpha-1b subunit may play a role in directed migration of immature neurons.Synonyms: Brain calcium channel III, CACH5, CACNL1A5, Calcium channel L type alpha-1 polypeptide isoform 5, Cav2.2, Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-gated calcium channel subunit alpha

ID gène: 774

NCBI Accession: NP_000709

UniProt: Q00975