IL1R1 anticorps (Biotin)

N° du produit ABIN2660926

Détail du produit anti-IL1R1 anticorps (Biotin)

Antigène: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1R1 est conjugé à/à la Biotin

Application: Screening Assay (ScA)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Clone: JAMA-147

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL1R1

Antigène: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Autre désignation: CD121a (IL1R1 Produits)

Synonymes: anticorps CD121A, anticorps D2S1473, anticorps IL-1R-alpha, anticorps IL1R, anticorps IL1RA, anticorps P80, anticorps CD121a, anticorps CD121b, anticorps IL-iR, anticorps Il1r-1, anticorps DER4, anticorps Fit-1, anticorps Ly84, anticorps ST2L, anticorps St2, anticorps St2-rs1, anticorps T1, anticorps T1/ST2, anticorps interleukin 1 receptor type 1, anticorps interleukin 1 receptor, type I, anticorps interleukin 1 receptor-like 1, anticorps IL1R1, anticorps Il1r1, anticorps Il1rl1

Sujet: CD121a is an 80 kD IL-1 receptor type I. It is a transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. CD121a binds the mature forms of IL-1α, IL-1β, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of binding IL-1.

Pathways: Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints