CYP2C9 anticorps (C-Term)

N° du produit ABIN2777004

Détail du produit anti-CYP2C9 anticorps

Antigène: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye, Porc, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2C9 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGMELFLFLT SILQNFNLKS LVDPKNLDTT PVVNGFASVP PFYQLCFIPV

Homologie: Cow: 85%, Dog: 83%, Guinea Pig: 75%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 77%, Rat: 83%, Sheep: 83%

Attributs du produit: This is a rabbit polyclonal antibody against CYP2C9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2C9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 490 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP2C9

Antigène: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Autre désignation: CYP2C9 (CYP2C9 Produits)

Synonymes: anticorps CPC9, anticorps CYP2C, anticorps CYP2C10, anticorps CYPIIC9, anticorps P450IIC9, anticorps cytochrome P450 family 2 subfamily C member 9, anticorps CYP2C9

Sujet: CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that CYP2C9 gene is polymorphic.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450 MP-4, P450 PB-1, P450IIC9, CYPIIC9
Protein Interaction Partner: POR, CYP2D6, STAMBP, STAT5A, RNF32, ECSIT, MAST1, CDC37, RAB3D,
Protein Size: 490

Poids moléculaire: 55 kDa

ID gène: 1559

NCBI Accession: NM_000771, NP_000762

UniProt: P11712