SOX4 anticorps (N-Term)

N° du produit ABIN2780469

Détail du produit anti-SOX4 anticorps

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: STASTGGKAD DPSWCKTPSG HIKRPMNAFM VWSQIERRKI MEQSPDMHNA

Specificité: Peptide immunogen shares 93 % with human SOX11.

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SOX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 474 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOX4

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Autre désignation: SOX4 (SOX4 Produits)

Synonymes: anticorps EVI16, anticorps AA682046, anticorps Sox-4, anticorps sox4, anticorps wu:fb82f08, anticorps wu:fq41g10, anticorps zgc:65850, anticorps zgc:77392, anticorps SRY-box 4, anticorps SRY box 4, anticorps SRY (sex determining region Y)-box 4, anticorps SRY (sex determining region Y)-box 4a, anticorps SOX4, anticorps Sox4, anticorps sox4a

Sujet: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EVI16
Protein Interaction Partner: TAF5, UBE2I, ELAVL1, TP53, MDM2, EP300, tat, SDCBP,
Protein Size: 474

Poids moléculaire: 47 kDa

ID gène: 6659

NCBI Accession: NM_003107, NP_003098

UniProt: Q06945