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ADAM15 anticorps (Middle Region)

ADAM15 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782601
  • Antigène Voir toutes ADAM15 Anticorps
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    Épitope
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 34
    • 13
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin
    Hôte
    • 28
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 28
    • 5
    Polyclonal
    Conjugué
    • 20
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAM15 est non-conjugé
    Application
    • 24
    • 13
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    QPAAPLCLQT ANTRGNAFGS CGRNPSGSYV SCTPRDAICG QLQCQTGRTQ
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 79%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ADAM15. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human ADAM15
    Top Product
    Discover our top product ADAM15 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 862 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    Autre désignation
    ADAM15 (ADAM15 Produits)
    Synonymes
    anticorps ADAM15, anticorps mdc15, anticorps MDC15, anticorps metargidin, anticorps tMDCVI, anticorps ADAM metallopeptidase domain 15, anticorps ADAM metallopeptidase domain 15 L homeolog, anticorps a disintegrin and metallopeptidase domain 15 (metargidin), anticorps ADAM15, anticorps adam15.L, anticorps adam15, anticorps Adam15
    Sujet
    ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: MDC15
    Protein Interaction Partner: BANP, NUP62, RBPMS, UBC, SP4, FHL3, FBXO6, SH3PXD2A, SRC, PTK6, MAPK3, MAPK1, NCK1, GRB2, SNX30, SH3RF3, SNX9, SH3GLB1, PACSIN3, ARHGEF6, ARHGEF7, SORBS2, YES1, NPHP1, LYN, LCK, HCK, FYN, SH3D19, SH3RF1, SORBS3, SNX33, SORBS1, TRIP13, SH3GL2, ABL1, MAD2L1
    Protein Size: 862
    Poids moléculaire
    70 kDa
    ID gène
    8751
    NCBI Accession
    NM_207196, NP_997079
    UniProt
    Q71S69
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