Ephrin A5 anticorps (N-Term)

N° du produit ABIN2790146

Détail du produit anti-Ephrin A5 anticorps

Antigène: Ephrin A5 (EFNA5)

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin A5 est non-conjugé

Application: Western Blotting (WB)

Séquence: EDSVPEDKTE RYVLYMVNFD GYSACDHTSK GFKRWECNRP HSPNGPLKFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against EFNA5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human EFNA5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 228 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Ephrin A5

Antigène: Ephrin A5 (EFNA5)

Autre désignation: EFNA5 (EFNA5 Produits)

Synonymes: anticorps EFNA5, anticorps af1, anticorps efl5, anticorps rags, anticorps eplg7, anticorps lerk7, anticorps AL-1, anticorps AV158822, anticorps EFL-5, anticorps Ephrin-A5, anticorps Epl7, anticorps LERK-7, anticorps RAGS, anticorps Lerk7, anticorps AF1, anticorps EFL5, anticorps EPLG7, anticorps GLC1M, anticorps LERK7, anticorps ephrin A5, anticorps EFNA5, anticorps efna5, anticorps Efna5

Sujet: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Alias Symbols: AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Protein Interaction Partner: MYC, GRIP1, SRC, EPHA7, EPHA4, EPHB2, EPHB1, EPHA5, EPHA3, EPHA2, EPHA8,
Protein Size: 228

Poids moléculaire: 24 kDa

ID gène: 1946

NCBI Accession: NM_001962, NP_001953

UniProt: P52803

Pathways: Signalisation RTK