HSPD1 anticorps

N° du produit ABIN3026480

Détail du produit anti-HSPD1 anticorps

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reactivité: Humain, Souris, Rat, Poulet, Singe, Chien, Hamster, Boeuf (Vache), Lapin, Porc, Mouton, Drosophila melanogaster, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aucune reactivité croisée: Bactéries, Nematode, Épinards (Spinacia oleracea)

Attributs du produit: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

Purification: Protein G affinity chromatography

Immunogène: Recombinant human HSP60 was used as the immunogen for this antibody.

Clone: LK1

Isotype: IgG1 kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.25-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the HSP60 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur HSPD1

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Autre désignation: HSP60 (HSPD1 Produits)

Synonymes: anticorps CPN60, anticorps GROEL, anticorps HLD4, anticorps HSP-60, anticorps HSP60, anticorps HSP65, anticorps HuCHA60, anticorps SPG13, anticorps chaperonin, anticorps cpn60, anticorps groel, anticorps hld4, anticorps hsp60, anticorps hsp65, anticorps spg13, anticorps 60kDa, anticorps Hsp60, anticorps 12, anticorps BP5, anticorps CG12101, anticorps Cpn60, anticorps Dmel\\CG12101, anticorps Dmhsp60, anticorps G62, anticorps HSP60A, anticorps Hsp60A, anticorps IEF16, anticorps Mmp-P1, anticorps SSP 7506, anticorps d-hsp60, anticorps hsp60A, anticorps l(1)10Ac, anticorps l(1)BP5, anticorps l(1)G8, anticorps l(1)HM21, anticorps l(1)L12, anticorps l(1)dp025, anticorps cb863, anticorps fa04a05, anticorps fb22d10, anticorps fi27b05, anticorps id:ibd2197, anticorps sb:cb144, anticorps wu:fa04a05, anticorps wu:fb22d10, anticorps wu:fi04a12, anticorps wu:fi27b05, anticorps MIF4, anticorps MNA2, anticorps mopA, anticorps groL, anticorps crpA, anticorps Hspd1-30p, anticorps heat shock protein family D (Hsp60) member 1, anticorps heat shock protein family D (Hsp60) member 1 S homeolog, anticorps 60 kDa heat shock protein, mitochondrial, anticorps heat shock protein 1 (chaperonin), anticorps Heat shock protein 60A, anticorps heat shock 60 protein 1, anticorps chaperone ATPase HSP60, anticorps molecular chaperone GroEL, anticorps thermosome subunit, anticorps chaperonin GroEL, anticorps mitochondrial chaperonin, anticorps heat shock protein family D member 1, anticorps HSPD1, anticorps hspd1.S, anticorps hspd1, anticorps LOC100414401, anticorps Hspd1, anticorps Hsp60A, anticorps HSP60, anticorps groEL, anticorps MMP_RS07785, anticorps groEl, anticorps LOC100136430

Sujet: This antibody recognizes a 60  kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

ID gène: 3329

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity