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MMP 9 anticorps (N-Term)

MMP9 Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 4A3 unconjugated
N° du produit ABIN307120
  • Antigène Voir toutes MMP 9 (MMP9) Anticorps
    MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
    Épitope
    • 16
    • 16
    • 15
    • 15
    • 13
    • 11
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 156
    • 85
    • 67
    • 36
    • 19
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 159
    • 47
    • 2
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 146
    • 64
    Monoclonal
    Conjugué
    • 93
    • 21
    • 15
    • 13
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MMP 9 est non-conjugé
    Application
    • 170
    • 78
    • 64
    • 40
    • 40
    • 36
    • 34
    • 34
    • 32
    • 32
    • 13
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    CLG4B, GELB, 92 kDa gelatinase, matrix metallopeptidase 9,The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92- kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
    Purification
    Protein A/G Chromatography
    Immunogène
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the N-terminus of the human MMP9 protein and mouse myeloma Ag8563 cells. Sequence common in rabbit, dog and pig
    Clone
    4A3
    Isotype
    IgG1
    Top Product
    Discover our top product MMP9 Anticorps primaire
  • Indications d'application
    Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry (1-5 μg/mL). Antibody is specific for the activated form of MMP9 only. These working concentrations are merely an indication. Optimal working concentrations should, however, be evaluated by serial dilutions by the customer.
    Restrictions
    For Research Use only
  • Buffer
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Antigène
    MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
    Autre désignation
    Matrix Metalloproteinase 9 (MMP9) (MMP9 Produits)
    Synonymes
    anticorps CLG4B, anticorps GELB, anticorps MANDP2, anticorps MMP-9, anticorps AW743869, anticorps B/MMP9, anticorps Clg4b, anticorps pro-MMP-9, anticorps mmp-9, anticorps fgMMP-9, anticorps mmp9, anticorps ZFMMP-9, anticorps wu:fb02g06, anticorps wu:fb07b05, anticorps wu:fi98c09, anticorps wu:fj05a08, anticorps zgc:64165, anticorps clg4b, anticorps gelb, anticorps mandp2, anticorps matrix metallopeptidase 9, anticorps collagenase, anticorps matrix metalloproteinase 9, anticorps matrix metallopeptidase 9 S homeolog, anticorps MMP9, anticorps RB3913, anticorps BPSS0666, anticorps Sbal_3732, anticorps Bcer98_0486, anticorps Shew185_0630, anticorps Shal_3056, anticorps Sbal195_0657, anticorps Lbys_3550, anticorps Palpr_2084, anticorps Mmp9, anticorps mmp9, anticorps mmp9.S
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events
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