STAT6 anticorps (AA 643-647)

N° du produit ABIN362577

Cité dans 1 publication. Cet anticorps anti-STAT6 Polyclonal Lapin (ABIN362577) détecte spécifiquement STAT6 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour STAT6 anticorps (AA 643-647) (ABIN362577)

Antigène: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STAT6 anticorps

Épitope: AA 643-647

Specificité: The antibody detects endogenous level of total STAT6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogène: Peptide sequence around AA 643-647 (P-A-T-I-K) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Références pour anticorps anti-STAT6 (ABIN362577)

Cheng, Wang, Xia, Yan, Tang, Chen, Zhang, Liu, Kong, Sjöberg, Folco, Libby, Liao, Shi: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." dans: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).

Détails sur STAT6

Antigène: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Autre désignation: STAT6

Sujet: Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Poids moléculaire: 110 kDa

NCBI Accession: NP_003144

UniProt: P42226

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response