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CARD11 anticorps (C-Term)

CARD11 Reactivité: Humain, Souris, Boeuf (Vache), Chien WB Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374314
  • Antigène Voir toutes CARD11 Anticorps
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 34
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Boeuf (Vache), Chien
    Hôte
    • 32
    • 1
    • 1
    • 1
    Chèvre
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CARD11 est non-conjugé
    Application
    • 27
    • 11
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    C-QRKTIWVDED QL
    Specificité
    This antibody detects CARD11 / CARMA1 at C-term.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Dog, CowSpecies reactivity (tested):Human
    Purification
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    Immunogène
    Peptide from the C Terminus of the protein sequence according to NP_115791.3 Genename: CARD11
    Top Product
    Discover our top product CARD11 Anticorps primaire
  • Indications d'application
    Peptide ELISA: Limit dilution 1: 32000. Western Blot: 1-3 μg/mL. Approx 150+65 kDa bands observed in lysates of cell line Jurkat(calculated MW of 135 kDa according to NP_115791.2). A similar pattern was observed inHEK293 transiently expressing CARD11. These bands are not observed in thenon-transfected HEK293.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • Antigène
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Autre désignation
    CARD11 / CARMA1 (CARD11 Produits)
    Synonymes
    anticorps BENTA, anticorps BIMP3, anticorps CARMA1, anticorps PPBL, anticorps 0610008L17Rik, anticorps 2410011D02Rik, anticorps CARD11, anticorps LOC100232755, anticorps caspase recruitment domain family member 11, anticorps caspase recruitment domain family, member 11, anticorps caspase recruitment domain-containing protein 11, anticorps CARD11, anticorps Card11, anticorps LOC100550812, anticorps card11
    Sujet
    CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
    ID gène
    84433
    NCBI Accession
    NP_115791
    UniProt
    Q9BXL7
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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