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ANTXR1 anticorps (AA 358-386)
ANTXR1
Reactivité: Humain
WB, IHC (p)
Hôte: Lapin
Polyclonal
RB15324
unconjugated
Détail du produit anti-ANTXR1 anticorps
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Antigène
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ANTXR1
(anthrax Toxin Receptor 1 (ANTXR1))
Épitope
Tous les épitopes à travers ANTXR1 Anticorps.
AA 358-386
Reactivité
Toutes les réactivités sur ANTXR1 Anticorps
Humain
Hôte
Toutes les hôtes sur ANTXR1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur ANTXR1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers ANTXR1 Anticorps
Cet anticorp ANTXR1 est non-conjugé
Application
Tous les applications à travers ANTXR1 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
Clone
RB15324
Isotype
Ig Fraction
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Information d'application
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Indications d'application
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Détails sur ANTXR1
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Antigène
ANTXR1
(anthrax Toxin Receptor 1 (ANTXR1))
Autre désignation
ANTXR1 (ANTXR1 Produits )
Synonymes
anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
Sujet
ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Poids moléculaire
62789
ID gène
84168
NCBI Accession
NP_060623 , NP_115584 , NP_444262
UniProt
Q9H6X2
Vus récemment
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