BMI1 anticorps (Intermediate Domain)
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- Antigène Voir toutes BMI1 Anticorps
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Épitope
- Intermediate Domain
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BMI1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- BMI-1 antibody was raised against a peptide corresponding to 15 amino acids near the center of human BMI-1.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Human BMI-1 (Intermediate Domain) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product BMI1 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: BMI-1 antibody can be used for detection of BMI-1 at 0.5 to 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
- Autre désignation
- BMI-1 / RNF51 (BMI1 Produits)
- Synonymes
- anticorps FLVI2/BMI1, anticorps PCGF4, anticorps RNF51, anticorps AW546694, anticorps Bmi-1, anticorps Pcgf4, anticorps bmi1, anticorps pcgf4, anticorps psc1, anticorps wu:fb17g03, anticorps wu:fd18f06, anticorps BMI-1, anticorps pcgf4b, anticorps bmi-1, anticorps bmi1-a, anticorps bmi1-b, anticorps bmi1b, anticorps rnf51, anticorps xbmi-1, anticorps BMI1 proto-oncogene, polycomb ring finger, anticorps BMI1 polycomb ring finger oncogene, anticorps Bmi1 polycomb ring finger oncogene, anticorps bmi1 polycomb ring finger oncogene 1a, anticorps bmi1 polycomb ring finger oncogene 1b, anticorps BMI1 proto-oncogene, polycomb ring finger L homeolog, anticorps BMI1, anticorps LOC100230513, anticorps Bmi1, anticorps bmi1a, anticorps bmi1b, anticorps bmi1.L
- Sujet
- The transcriptional repressor BMI-1 was first identified as a proto-oncogene frequently activated by Moloney murine leukemia proviral insertions in mice and cooperating with c-myc in the generation of mouse lymphomas . BMI-1 is involved in segment specification, cell growth and maintenance, transcriptional regulation, and chromatin modification. A major target of BMI-1 is the ink4a locus which encodes tumor suppressor proteins p16 and p19Arf, which are important in tumor progression and thought to be critical in cell proliferation and senescence (2). Recent studies have also shown that BMI-1 is required for the maintenance of adult normal and leukemic stem cells (3), suggesting that BMI-1 could an attractive therapeutic target for stem cell proliferation and renewal as well as for anti-cancer strategies.Synonyms: BMI1, PCGF4, Polycomb group RING finger protein 4, RING finger protein 51
- ID gène
- 648
- UniProt
- P35226
- Pathways
- Cycle Cellulaire, Autophagy
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