NEK11 anticorps (Middle Region)

N° du produit ABIN502997

Détail du produit anti-NEK11 anticorps

Antigène: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Épitope: Middle Region

Reactivité: Humain, Rat, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEK11 est non-conjugé

Application: Western Blotting (WB)

Séquence: KEIRNEGSQP AYRTNQQDSD IEALARCLEN VLGCTSLDTK TITTMAEDMS

Homologie: Cow: 77%, Horse: 100%, Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against NEK11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NEK11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 645 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NEK11

Antigène: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Autre désignation: NEK11 (NEK11 Produits)

Synonymes: anticorps nek11, anticorps MGC147549, anticorps 4932416N14Rik, anticorps NIMA-related kinase 11, anticorps NIMA (never in mitosis gene a)-related expressed kinase 11, anticorps NIMA related kinase 11, anticorps nek11, anticorps Nek11, anticorps NEK11

Sujet: NEK11 is a member of the never in mitosis gene A family of kinases. NEK11 localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. It appears to play roles in DNA replication and response to genotoxic stress. NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2937 AB071996.1 1-2937
Alias Symbols: FLJ23495
Protein Interaction Partner: MYC, HSP90AA1, APP, NEK11, NEK2,
Protein Size: 645

Poids moléculaire: 74 kDa

ID gène: 79858

NCBI Accession: NM_024800, NP_079076

UniProt: Q8NG66