PRR5 anticorps (C-Term)

N° du produit ABIN504071

Détail du produit anti-PRR5 anticorps

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRR5 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD

Homologie: Cow: 100%, Dog: 91%, Horse: 86%, Human: 100%, Pig: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRR5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PRR5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 379 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRR5

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Autre désignation: PRR5 (PRR5 Produits)

Synonymes: anticorps AU043908, anticorps Arhgap8, anticorps C030017C09Rik, anticorps C78947, anticorps Protor-1, anticorps Protor1, anticorps FLJ20185k, anticorps PP610, anticorps PROTOR-1, anticorps PROTOR1, anticorps pp610, anticorps protor1, anticorps protor2, anticorps proline rich 5 (renal), anticorps proline rich 5, anticorps proline rich 5 L homeolog, anticorps Prr5, anticorps PRR5, anticorps prr5.L

Sujet: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: PP610, PROTOR1, PROTOR-1, FLJ20185k,
Protein Interaction Partner: MTOR, BRCA1, UBC, RICTOR, MAPKAP1, MLST8,
Protein Size: 293

Poids moléculaire: 32 kDa

ID gène: 55615

NCBI Accession: NM_001017528, NP_056181

Pathways: Signalisation PI3K-Akt