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FREM2 anticorps (Center)

FREM2 Reactivité: Humain, Souris WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783636
  • Antigène Voir toutes FREM2 Anticorps
    FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))
    Épitope
    • 5
    • 3
    • 1
    • 1
    Center
    Reactivité
    Humain, Souris
    Hôte
    • 10
    • 1
    Lapin
    Clonalité
    • 11
    Polyclonal
    Conjugué
    • 7
    • 2
    • 1
    • 1
    Cet anticorp FREM2 est non-conjugé
    Application
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts with Human and Mouse FREM2 and is predicted to not cross-react with other FRAS members. This antibody recognizes both isoforms of FREM2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    19 amino acid peptide near the center of Human FREM2
    Top Product
    Discover our top product FREM2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))
    Autre désignation
    FREM2 (FREM2 Produits)
    Synonymes
    anticorps 6030440P17Rik, anticorps 8430406N05Rik, anticorps Gm409, anticorps b2b1562Clo, anticorps my, anticorps ne, anticorps nv1, anticorps RGD1566012, anticorps FRAS1 related extracellular matrix protein 2, anticorps Fras1 related extracellular matrix protein 2, anticorps FREM2, anticorps Frem2
    Sujet
    FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.Synonyms: ECM3 homolog, FRAS1-related extracellular matrix protein 2
    ID gène
    341640
    NCBI Accession
    NP_997244
    UniProt
    Q5SZK8
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