Aperçu des produits pour anti-Caspase 8 (CASP8) Anticorps

Full name:
anti-Caspase 8, Apoptosis-Related Cysteine Peptidase Anticorps (CASP8)
Chez www.anticorps-enligne.fr sont 397 Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Anticorps de 36 de différents fournisseurs disponibles. De plus, nous expédions Caspase 8 Kits (70) et Caspase 8 Protéines (29) et beaucoup plus de produits pour cette protéine. Un total de 518 Caspase 8 produits sont actuellement listés.
Synonymes:
ALPS2B, CAP4, Casp-8, CASP8, casp8-A, caspase-8, FLICE, MACH, MCH5, xCaspase-8, zgc:92075
afficher tous les anticorps Gène GeneID UniProt
CASP8 12370 O89110
CASP8 64044  
CASP8 841 Q14790

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anti-Caspase 8 Anticorps mieux référencés

  1. Human Polyclonal Caspase 8 Primary Antibody pour IF (cc), IF (p) - ABIN724205 : Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. dans Molecular and cellular biochemistry 2011 (PubMed)
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  2. Human Monoclonal Caspase 8 Primary Antibody pour CyTOF, FACS - ABIN252488 : Berges, Fuchs, Opelz, Daniel, Naujokat: Helenalin suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms. dans Molecular immunology 2009 (PubMed)
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  3. Cow (Bovine) Polyclonal Caspase 8 Primary Antibody pour WB - ABIN222878 : Peluffo, Stouffer, Tesone: Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum. dans American journal of physiology. Endocrinology and metabolism 2007 (PubMed)
    Show all 5 references for 222878

  4. Mouse (Murine) Polyclonal Caspase 8 Primary Antibody pour WB - ABIN223020 : Woods, Burns, Bradford, Ross, Kosyk, Swenberg, Cunningham, Rusyn: WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. dans Toxicological sciences : an official journal of the Society of Toxicology 2007 (PubMed)
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  5. Human Polyclonal Caspase 8 Primary Antibody pour ELISA, WB - ABIN1532005 : Xu, Xu, Zhou, Zhuang, Wang, Boerner, Wu: Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. dans The Journal of biological chemistry 2013 (PubMed)
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  6. Human Polyclonal Caspase 8 Primary Antibody pour ELISA, WB - ABIN1536108 : Liu, Huang, Liu, Li, Yang, Dou, Liu: Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation. dans Toxicology in vitro : an international journal published in association with BIBRA 2014 (PubMed)
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  7. Human Polyclonal Caspase 8 Primary Antibody pour WB - ABIN783312 : Sánchez, Xu, Juo, Kakizaka, Blenis, Yuan: Caspase-8 is required for cell death induced by expanded polyglutamine repeats. dans Neuron 1999 (PubMed)
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  8. Human Polyclonal Caspase 8 Primary Antibody pour IHC, WB - ABIN222959 : Mahul-Mellier, Strappazzon, Petiot, Chatellard-Causse, Torch, Blot, Freeman, Kuhn, Garin, Verna, Fraboulet, Sadoul: Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death. dans The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for 222959

  9. Human Polyclonal Caspase 8 Primary Antibody pour FACS, IF - ABIN390474 : Ji, Gu, Hu, Wang, Liang, Xia, Lu, Song, Fu, Wang: Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality. dans Human reproduction (Oxford, England) 2009 (PubMed)
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  10. Human Polyclonal Caspase 8 Primary Antibody pour IF, WB - ABIN1105679 : Muzio, Chinnaiyan, Kischkel, ORourke, Shevchenko, Ni, Scaffidi, Bretz, Zhang, Gentz, Mann, Krammer, Peter, Dixit: FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. dans Cell 1996 (PubMed)
    Show all 2 references for 1105679

Plus d’anticorps contre Caspase 8 partenaires d’interaction

Xenopus laevis Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC (Montrer AMD1 Anticorps)-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53 (Montrer TP53 Anticorps)-overexpressed apoptotic embryos.

  2. tail regression at metamorphosis implicates an apoptotic pathway inducible by T(3) hormone in an organ autonomous manner and involving the cell death executioners BH3 interacting domain death agonist (Montrer BID Anticorps) and Caspases-2 and -8

Mouse (Murine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Statistically significant increases in the expression of Fas (Montrer FAS Anticorps) and caspase-8 were observed, along with other molecules involved in the extrinsic apoptotic pathway such as Dapk1 (Montrer DAPK1 Anticorps), Traf3 (Montrer TRAF3 Anticorps), Tnsf12, Tnfrsf1A (Montrer TNFRSF1A Anticorps) and Ripk1 (Montrer RIPK1 Anticorps).

  2. Results suggest that caspase-8 could regulate receptor-interacting protein 3 (RIP3 (Montrer RIPK3 Anticorps))-mediated necroptosis.

  3. we show that caspase-8 activity promotes cell-intrinsic cytokine expression, independent of its role in cell death in response to Yersinia infection

  4. Data indicate that NLRC4 (Montrer NLRC4 Anticorps) activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 (Montrer IL18 Anticorps) release, and implicate Caspase-8 in NLRC4 (Montrer NLRC4 Anticorps) inflammasome responses in vivo by generation of doubly deficient in Caspase-1 (Montrer CASP1 Anticorps) and Caspase-8.

  5. ING4 (Montrer ING4 Anticorps) might suppress proliferation and enhance apoptosis in human malignant melanoma cells by activating Fas (Montrer FAS Anticorps)-induced apoptosis in a caspase-8-dependent pathway.

  6. studies have uncovered the combined actions of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and caspase 8 leading to IL-1beta (Montrer IL1B Anticorps) maturation and the directionality of IL-1beta (Montrer IL1B Anticorps) in driving disease inPstpip2(cmo (Montrer PSTPIP2 Anticorps))mice.

  7. Chronic TLR Stimulation Controls NLRP3 (Montrer NLRP3 Anticorps) Inflammasome Activation through IL-10 (Montrer IL10 Anticorps) Mediated Regulation of NLRP3 (Montrer NLRP3 Anticorps) Expression and Caspase-8 Activation

  8. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  9. Data indicate that receptor-interacting serine-threonine kinase 3 (RIPK3 (Montrer RIPK3 Anticorps)) deletion prevents inflammatory phenotypes in CreLysM (lysozyme (Montrer LYZ Anticorps) M) Casp8fl/fl (caspase 8) mice.

  10. CASP8 deletion did not affect the overall number of microglia expressing the pan (Montrer SUPT6H Anticorps) specific microglia marker, Iba1 (Montrer AIF1 Anticorps)

Human Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Insertion genotype of CASP8 rs3834129 polymorphisms showed risk in CAD (Montrer CAD Anticorps). CASP8 rs3769818 activates intronic cryptic donor.

  2. Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase (Montrer KARS Anticorps) in exosomes from colorectal cancer cells.

  3. Fisetin inhibited Triple-Negative Breast Cancer Cells cell division and induced apoptosis, which was associated with mitochondrial membrane permeabilization and the activation of caspase-9 (Montrer CASP9 Anticorps) and caspase-8, as well as the cleavage of poly(ADP-ribose) polymerase-1 (Montrer PARP1 Anticorps).

  4. Caspase-8 can serve in two distinct roles in response to TRAIL receptor engagement, as a scaffold for assembly of a Caspase-8-FADD-RIPK1 "FADDosome" complex, leading to NFkappaB-dependent inflammation, or as a protease that promotes apoptosis.

  5. Using the tDED filament structure as a template, structural analyses reveal the interaction surfaces between FADD (Montrer FADD Anticorps) and caspase-8 and the distinct mechanisms of regulation by cFLIP (Montrer CFLAR Anticorps) and MC159 through comingling and capping, respectively.

  6. our novel findings expand our understanding of the key mechanisms underlying the anti-apoptotic functions of caspase-8 which may act as a critical block to existing antitumour therapies.

  7. Proteases caspase-1 (Montrer CASP1 Anticorps) and caspase-8 have redundant roles in cleaving IL-1beta (Montrer IL1B Anticorps) and promoting osteomyelitis. [review]

  8. Dasatinib, a c-Src (Montrer SRC Anticorps) inhibitor, dephosphorylated caspase-8 to facilitate necroptosis, rather than apoptosis, in paclitaxel-treated p-Casp8-expressing lung adenocarcinoma cells.

  9. Loss of function mutations in FAT1 (Montrer FAT1 Anticorps) and CASP8 prevent cell adhesion and promote cell migration and proliferation in oral squamous cell carcinoma cell lines.

  10. Dysregulation of a potassium channel (Montrer KCNAB2 Anticorps), THIK-1 (Montrer KCNK13 Anticorps), targeted by caspase-8, accelerates cell shrinkage.

Cow (Bovine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. S. aureus-induced apoptosis in bovine mammary epithelial cells apoptosis was mitigated by caspase-3 (Montrer CASP3 Anticorps) and caspase-8 inhibitors, suggesting that apoptosis is initiated via caspase-8 activation.

  2. Endothelial cell apoptosis by H. somnus-activated platelets required activation of both caspase-8 and caspase-9 (Montrer CASP9 Anticorps).

Pig (Porcine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Nitric oxide-dependent increase in caspase-8 mRNA levels is associated with phosphorylation of STAT-1 (Montrer STAT1 Anticorps) at Ser (Montrer SIGLEC1 Anticorps)-727 and STAT1 (Montrer STAT1 Anticorps) binding to the caspase-8 promoter in cultured lung endothelial cells.

  2. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (Montrer TNF Anticorps), IL-6 (Montrer IL6 Anticorps), IL-12p40, IL-1beta (Montrer IL1B Anticorps), and resulted in increased expression of the apoptosis initiator caspase-8 and bcl2L1 (Montrer BCL2L1 Anticorps).

Zebrafish Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Induction of apoptosis through targeted activation of caspase (Montrer CASP3 Anticorps) by tamoxifen (ATTAC(TM)) further expands the repertoire of genetic tools for conditional interrogation of cellular functions.

  2. Targeted gene knockdown of TNFRSF1B (Montrer TNFRSF1B Anticorps) in zebrafish embryos results in the induction of a caspase-8, caspase-2 (Montrer CASP2 Anticorps) and P53 (Montrer TP53 Anticorps)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (Montrer CASP3 Anticorps).

  3. These results show that zebrafish casp8 has a structure and function similar to mammalian CASP8 orthologs and the role of caspase-8 in the apoptotic signal pathway has been conserved over at least 450 million years of vertebrate evolution.

Caspase 8 (CASP8) profil antigène

Antigen Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

Alternative names and synonyms associated with Caspase 8 (CASP8)

  • caspase 8, apoptosis-related cysteine peptidase (casp8) anticorps
  • death related ced-3/Nedd2-like protein (Dredd) anticorps
  • caspase 8, apoptosis-related cysteine peptidase (CASP8) anticorps
  • caspase-8 (AaeL_AAEL014148) anticorps
  • caspase-8 (casp8) anticorps
  • caspase 8 (LOC100222284) anticorps
  • caspase 8 (Casp8) anticorps
  • caspase 8 (LOC100348477) anticorps
  • ALPS2B anticorps
  • CAP4 anticorps
  • Casp-8 anticorps
  • CASP8 anticorps
  • casp8-A anticorps
  • caspase-8 anticorps
  • FLICE anticorps
  • MACH anticorps
  • MCH5 anticorps
  • xCaspase-8 anticorps
  • zgc:92075 anticorps

Protein level used designations for CASP8

caspase-8 , xcaspase 8 , death related ced-3/Nedd2-like protein , GLEAN_14026 , caspase 8, apoptosis-related cysteine peptidase , caspase 8 , caspase-8-like , DEATH effector domain caspase , Fas-linked ICE-like protease , FADD-homologous ICE/CED-3-like protease , FADD-like ICE , ICE-like apoptotic protease 5 , MACH-alpha-1/2/3 protein , MACH-beta-1/2/3/4 protein , MORT1-associated ced-3 homolog , apoptotic cysteine protease , apoptotic protease Mch-5 , caspase 8, apoptosis-related cysteine protease , caspase-8a , cysteine protease

GENE ID SPECIES
373559 Xenopus laevis
661095 Tribolium castaneum
702781 Macaca mulatta
5563818 Aedes aegypti
100049400 Oryzias latipes
100066502 Equus caballus
100142684 Felis catus
100172115 Pongo abelii
100222284 Taeniopygia guttata
100472842 Ailuropoda melanoleuca
100579132 Hydra magnipapillata
100586183 Nomascus leucogenys
12370 Mus musculus
64044 Rattus norvegicus
100348477 Oryctolagus cuniculus
841 Homo sapiens
746477 Pan troglodytes
507481 Bos taurus
395284 Gallus gallus
488473 Canis lupus familiaris
595105 Sus scrofa
101107334 Ovis aries
58022 Danio rerio
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