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Aperçu des produits pour anti-Caspase 8 (CASP8) Anticorps

Full name:
anti-Caspase 8, Apoptosis-Related Cysteine Peptidase Anticorps (CASP8)
Chez sont 391 Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Anticorps de 35 de différents fournisseurs disponibles. De plus, nous expédions Caspase 8 Kits (58) et Caspase 8 Protéines (25) et beaucoup plus de produits pour cette protéine. Un total de 494 Caspase 8 produits sont actuellement listés.
ALPS2B, CAP4, Casp-8, CASP8, casp8-A, caspase-8, FLICE, MACH, MCH5, xCaspase-8, zgc:92075
afficher tous les anticorps Gène GeneID UniProt
CASP8 12370 O89110
CASP8 64044  
CASP8 841 Q14790

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anti-Caspase 8 Anticorps mieux référencés

  1. Human Polyclonal Caspase 8 Primary Antibody pour IF (cc), IF (p) - ABIN724205 : Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. dans Molecular and cellular biochemistry 2011 (PubMed)
    Show all 9 references for ABIN724205

  2. Cow (Bovine) Polyclonal Caspase 8 Primary Antibody pour WB - ABIN222878 : Peluffo, Stouffer, Tesone: Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum. dans American journal of physiology. Endocrinology and metabolism 2007 (PubMed)
    Show all 5 references for ABIN222878

  3. Mouse (Murine) Polyclonal Caspase 8 Primary Antibody pour WB - ABIN223020 : Woods, Burns, Bradford, Ross, Kosyk, Swenberg, Cunningham, Rusyn: WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. dans Toxicological sciences : an official journal of the Society of Toxicology 2007 (PubMed)
    Show all 4 references for ABIN223020

  4. Human Polyclonal Caspase 8 Primary Antibody pour ELISA, WB - ABIN1532005 : Xu, Xu, Zhou, Zhuang, Wang, Boerner, Wu: Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. dans The Journal of biological chemistry 2013 (PubMed)
    Show all 3 references for ABIN1532005

  5. Human Polyclonal Caspase 8 Primary Antibody pour ELISA, WB - ABIN1536108 : Liu, Huang, Liu, Li, Yang, Dou, Liu: Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation. dans Toxicology in vitro : an international journal published in association with BIBRA 2014 (PubMed)
    Show all 3 references for ABIN1536108

  6. Human Polyclonal Caspase 8 Primary Antibody pour IF, WB - ABIN1105679 : Muzio, Chinnaiyan, Kischkel, ORourke, Shevchenko, Ni, Scaffidi, Bretz, Zhang, Gentz, Mann, Krammer, Peter, Dixit: FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. dans Cell 1996 (PubMed)
    Show all 2 references for ABIN1105679

  7. Human Polyclonal Caspase 8 Primary Antibody pour IHC, WB - ABIN222959 : Mahul-Mellier, Strappazzon, Petiot, Chatellard-Causse, Torch, Blot, Freeman, Kuhn, Garin, Verna, Fraboulet, Sadoul: Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death. dans The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN222959

  8. Human Polyclonal Caspase 8 Primary Antibody pour FACS, IF - ABIN390474 : Ji, Gu, Hu, Wang, Liang, Xia, Lu, Song, Fu, Wang: Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality. dans Human reproduction (Oxford, England) 2009 (PubMed)
    Show all 2 references for ABIN390474

  9. Human Polyclonal Caspase 8 Primary Antibody pour WB - ABIN783312 : Sánchez, Xu, Juo, Kakizaka, Blenis, Yuan: Caspase-8 is required for cell death induced by expanded polyglutamine repeats. dans Neuron 1999 (PubMed)
    Show all 2 references for ABIN783312

Plus d’anticorps contre Caspase 8 partenaires d’interaction

Xenopus laevis Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC (Montrer AMD1 Anticorps)-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53 (Montrer TP53 Anticorps)-overexpressed apoptotic embryos.

  2. tail regression at metamorphosis implicates an apoptotic pathway inducible by T(3) hormone in an organ autonomous manner and involving the cell death executioners BH3 interacting domain death agonist (Montrer BID Anticorps) and Caspases-2 and -8

Mouse (Murine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. studies have uncovered the combined actions of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and caspase 8 leading to IL-1beta (Montrer IL1B Anticorps) maturation and the directionality of IL-1beta (Montrer IL1B Anticorps) in driving disease inPstpip2(cmo (Montrer PSTPIP2 Anticorps))mice.

  2. Chronic TLR Stimulation Controls NLRP3 (Montrer NLRP3 Anticorps) Inflammasome Activation through IL-10 (Montrer IL10 Anticorps) Mediated Regulation of NLRP3 (Montrer NLRP3 Anticorps) Expression and Caspase-8 Activation

  3. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  4. Data indicate that receptor-interacting serine-threonine kinase 3 (RIPK3 (Montrer RIPK3 Anticorps)) deletion prevents inflammatory phenotypes in CreLysM (lysozyme (Montrer LYZ Anticorps) M) Casp8fl/fl (caspase 8) mice.

  5. CASP8 deletion did not affect the overall number of microglia expressing the pan (Montrer SUPT6H Anticorps) specific microglia marker, Iba1 (Montrer AIF1 Anticorps)

  6. We observed that NDMP generation was dependent on the extrinsic caspase (Montrer CASP3 Anticorps) apoptotic pathway (caspase 3 (Montrer CASP3 Anticorps) and caspase 8), cAMP activation of PKA but not of Epac (Montrer RAPGEF3 Anticorps), and on activation of MLCK (Montrer MYLK Anticorps).

  7. Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 (Montrer CASP1 Anticorps) and the Noncanonical Caspase-8 Inflammasomes.

  8. Casp8-dependent migration of enterocytes is likely involved in intestinal physiology and inflammation-related pathophysiology.

  9. NLRP3 (Montrer NLRP3 Anticorps) inflammasomes directly utilize caspase-8 as both a pro-apoptotic initiator and major IL-1beta (Montrer IL1B Anticorps)-converting protease

  10. The non-receptor tyrosine kinase (Montrer TNK1 Anticorps) Tec (Montrer NR4A3 Anticorps) controls assembly and activity of the noncanonical caspase-8 inflammasome.

Human Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Findings showed that, in MDA-MB-231 cells, casp-8 might play some unusual roles which should be better explored, in order to understand whether it might be identified as a molecular therapeutic target.

  2. Study showed that TRAIL and caspase-8 expression decreased in human osteosarcoma, resulting in increased cell proliferation, and reduced cell apoptosis suggesting they play important roles in the occurrence, development, and prognosis of osteosarcoma.

  3. evidence that Articulatin-D efficiently activates caspase-8 involved in extrinsic pathway of apoptosis induction, which ultimately results in caspase-3 (Montrer CASP3 Anticorps)-dependent DNA fragmentation of Jurkat cells.

  4. Copper induces the activation of apoptosis through casp3 (Montrer CASP3 Anticorps)/casp8/casp9 (Montrer CASP9 Anticorps)/AIF (Montrer AIFM1 Anticorps)/TP53 (Montrer TP53 Anticorps) signaling pathways. Suggest that apoptosis activation mechanism is dependent on the concentration, time of exposure to Cu and cell type.

  5. our findings indicate that the expression levels of P-GP (Montrer ABCB4 Anticorps), MYC (Montrer MYC Anticorps), caspase-8, and AKT3 (Montrer AKT3 Anticorps) are candidate biomarkers of cell sensitivity to PLKis.

  6. Overexpression of CASP8 is associated with lung cancer.

  7. Thymoquinone inhibitory effects were associated with inhibition of NF-kappaB (Montrer NFKB1 Anticorps) and altered expression of its downstream effectors IL-8 (Montrer IL8 Anticorps) and its receptors, the anti-apoptotic Bcl-2 (Montrer BCL2 Anticorps), Bcl-xL (Montrer BCL2L1 Anticorps), X-IAP (Montrer ALPI Anticorps), and FLIP, as well as the pro-apoptotic TRAIL-R1, caspase-8, caspase-9 (Montrer CASP9 Anticorps), Bcl-xS (Montrer BCL2L1 Anticorps), and cytochrome c (Montrer CYCS Anticorps).

  8. Direct non-homotypic interactions of HPV18 E2 transactivation domain (TAD (Montrer CRTAM Anticorps)) with alpha2/alpha5 helices of procaspase-8 death effector domain-B (DED (Montrer AATF Anticorps)-B) mediate cell death in HEK293 cells.

  9. CASP8 rs3769823 and IDH2 (Montrer IDH2 Anticorps) rs4561444 were as the potential functional variants in high-linkage disequilibrium with these single nucleotide polymorphisms, respectively. The IDH2 (Montrer IDH2 Anticorps) mRNA levels were down-regulated in oesophageal squamous cell carcinoma.

  10. The CASP8 rs700635[C] allele, which is associated with increased risk of cutaneous basal-cell carcinoma and breast cancer, is protective against prostate cancer.

Cow (Bovine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. S. aureus-induced apoptosis in bovine mammary epithelial cells apoptosis was mitigated by caspase-3 (Montrer CASP3 Anticorps) and caspase-8 inhibitors, suggesting that apoptosis is initiated via caspase-8 activation.

  2. Endothelial cell apoptosis by H. somnus-activated platelets required activation of both caspase-8 and caspase-9 (Montrer CASP9 Anticorps).

Pig (Porcine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Nitric oxide-dependent increase in caspase-8 mRNA levels is associated with phosphorylation of STAT-1 (Montrer STAT1 Anticorps) at Ser (Montrer SIGLEC1 Anticorps)-727 and STAT1 (Montrer STAT1 Anticorps) binding to the caspase-8 promoter in cultured lung endothelial cells.

  2. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (Montrer TNF Anticorps), IL-6 (Montrer IL6 Anticorps), IL-12p40, IL-1beta (Montrer IL1B Anticorps), and resulted in increased expression of the apoptosis initiator caspase-8 and bcl2L1 (Montrer BCL2L1 Anticorps).

Zebrafish Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Targeted gene knockdown of TNFRSF1B (Montrer TNFRSF1B Anticorps) in zebrafish embryos results in the induction of a caspase-8, caspase-2 (Montrer CASP2 Anticorps) and P53 (Montrer TP53 Anticorps)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (Montrer CASP3 Anticorps).

  2. These results show that zebrafish casp8 has a structure and function similar to mammalian CASP8 orthologs and the role of caspase-8 in the apoptotic signal pathway has been conserved over at least 450 million years of vertebrate evolution.

Caspase 8 (CASP8) profil antigène

Antigen Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

Alternative names and synonyms associated with Caspase 8 (CASP8)

  • caspase 8, apoptosis-related cysteine peptidase (casp8) anticorps
  • death related ced-3/Nedd2-like protein (Dredd) anticorps
  • caspase 8, apoptosis-related cysteine peptidase (CASP8) anticorps
  • caspase-8 (AaeL_AAEL014148) anticorps
  • caspase-8 (casp8) anticorps
  • caspase 8 (LOC100222284) anticorps
  • caspase 8 (Casp8) anticorps
  • caspase 8 (LOC100348477) anticorps
  • ALPS2B anticorps
  • CAP4 anticorps
  • Casp-8 anticorps
  • CASP8 anticorps
  • casp8-A anticorps
  • caspase-8 anticorps
  • FLICE anticorps
  • MACH anticorps
  • MCH5 anticorps
  • xCaspase-8 anticorps
  • zgc:92075 anticorps

Protein level used designations for CASP8

caspase-8 , xcaspase 8 , death related ced-3/Nedd2-like protein , GLEAN_14026 , caspase 8, apoptosis-related cysteine peptidase , caspase 8 , caspase-8-like , DEATH effector domain caspase , Fas-linked ICE-like protease , FADD-homologous ICE/CED-3-like protease , FADD-like ICE , ICE-like apoptotic protease 5 , MACH-alpha-1/2/3 protein , MACH-beta-1/2/3/4 protein , MORT1-associated ced-3 homolog , apoptotic cysteine protease , apoptotic protease Mch-5 , caspase 8, apoptosis-related cysteine protease , caspase-8a , cysteine protease

373559 Xenopus laevis
661095 Tribolium castaneum
702781 Macaca mulatta
5563818 Aedes aegypti
100049400 Oryzias latipes
100066502 Equus caballus
100142684 Felis catus
100172115 Pongo abelii
100222284 Taeniopygia guttata
100472842 Ailuropoda melanoleuca
100579132 Hydra magnipapillata
100586183 Nomascus leucogenys
12370 Mus musculus
64044 Rattus norvegicus
100348477 Oryctolagus cuniculus
841 Homo sapiens
746477 Pan troglodytes
507481 Bos taurus
395284 Gallus gallus
488473 Canis lupus familiaris
595105 Sus scrofa
101107334 Ovis aries
58022 Danio rerio
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