Aperçu des produits pour anti-PTK2B (PTK2B) Anticorps

Full name:
anti-PTK2B Protein tyrosine Kinase 2 beta Anticorps (PTK2B)
Chez www.anticorps-enligne.fr sont 257 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions PTK2B Kits (21) et PTK2B Protéines (14) et beaucoup plus de produits pour cette protéine. Un total de 310 PTK2B produits sont actuellement listés.
Synonymes:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

Réactivités les plus populaires pour anti-PTK2B (PTK2B) Anticorps

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anti-Rat (Rattus) PTK2B Anticorps:

anti-Mouse (Murine) PTK2B Anticorps:

anti-Human PTK2B Anticorps:

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anti-PTK2B Anticorps mieux référencés

  1. Human Polyclonal PTK2B Primary Antibody pour IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. dans The Journal of clinical investigation 2004 (PubMed)
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  2. Human Monoclonal PTK2B Primary Antibody pour IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. dans Experimental hematology 2004 (PubMed)
    Show all 3 references for 1724705

  3. Human Polyclonal PTK2B Primary Antibody pour ELISA, WB - ABIN1533144 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. dans Nature 1995 (PubMed)
    Show all 2 references for 1533144

  4. Human Polyclonal PTK2B Primary Antibody pour IHC, ELISA - ABIN1532112 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. dans Genomics 1997 (PubMed)
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  5. Human Polyclonal PTK2B Primary Antibody pour IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. dans Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for 197440

  6. Human Polyclonal PTK2B Primary Antibody pour IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. dans Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody pour WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. dans American journal of physiology. Cell physiology 2004 (PubMed)

  8. Human Polyclonal PTK2B Primary Antibody pour ICC, IF - ABIN257536 : Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment. dans Cell reports 2017 (PubMed)

Plus d’anticorps contre PTK2B partenaires d’interaction

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex upregulation of OPN (Montrer SPP1 Anticorps) expression is mediated by transcription factor SOX9 (Montrer SOX9 Anticorps) in an mTOR (Montrer FRAP1 Anticorps)-independent manner. Moreover, ablation of OPN (Montrer SPP1 Anticorps) by deficient TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex contributed to inactivation of AKT (Montrer AKT1 Anticorps) in TSC (Montrer SLC12A3 Anticorps) cells

  2. Our results suggest that increasing Akt (Montrer AKT1 Anticorps)/ NF-kappaB (Montrer NFKB1 Anticorps) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (Montrer PTEN Anticorps)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (Montrer PTEN Anticorps) is a key regulatory player in the PI3K/PTEN (Montrer PTEN Anticorps)/AKT (Montrer AKT1 Anticorps) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (Montrer AKT1 Anticorps) activation that tracks both the biochemical state and the physical location of Akt (Montrer AKT1 Anticorps), is reported.

  6. Psgl-1 (Montrer SELPLG Anticorps) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (Montrer AKT1 Anticorps) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (Montrer HSP90 Anticorps) and the PI3K/AKT (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) pathway in prostate cancer.

  8. results show that Pyk2 contributes to cytotoxic T lymphocyte(CTL) migration by regulating detachment of CTL at the trailing edge, which could explain why Pyk2 is important for chemotactic and migratory responses.

  9. Furthermore, Leishmania RNA virus 1-induced TLR-3 (Montrer TLR3 Anticorps) activation promoted parasite persistence by enhancing macrophage survival through Akt (Montrer AKT1 Anticorps) activation in a manner partially dependent on miR (Montrer MLXIP Anticorps)-155.

  10. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (Montrer CCL2 Anticorps) proliferation, and was associated with inhibition of PI3K/Akt (Montrer AKT1 Anticorps) signaling pathway through activation of GPR120 (Montrer O3FAR1 Anticorps).

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Our findings suggest that Pyk2 plays an important role in the coordination of stabilization of beta-catenin (Montrer CTNNB1 Anticorps) in the crosstalk between Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) and Wnt (Montrer WNT2 Anticorps)/Ca(2 (Montrer CA2 Anticorps)+) signaling pathways upon Wnt3a (Montrer WNT3A Anticorps) stimulation in differentiating hNPCs.

  2. STIM1 (Montrer STIM1 Anticorps)-induced Ca(2 (Montrer CA2 Anticorps)+) signaling activates Pyk2 to inhibit the interaction of VE-PTP (Montrer PTPRB Anticorps) and VE-cadherin (Montrer CDH5 Anticorps) and hence increase endothelial permeability.

  3. Ascites and CCL18 (Montrer CCL18 Anticorps) stimulate the phosphorylation and expression of Pyk2, which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (Montrer PIK3CA Anticorps)-Akt/PKB (Montrer AKT1 Anticorps) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 is a common downstream effector of ErbB (Montrer EGFR Anticorps) and IL8 (Montrer IL8 Anticorps) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 is a key downstream signaling molecules of CCR7 (Montrer CCR7 Anticorps) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (Montrer LPXN Anticorps).

  10. Src (Montrer SRC Anticorps) has a role in priming Pyk2 (but not FAK (Montrer PTK2 Anticorps)) phosphorylation and subsequent activation downstream of integrins

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B profil antigène

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • protein tyrosine kinase 2 beta (PTK2B) anticorps
  • protein tyrosine kinase 2 beta (Ptk2b) anticorps
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) anticorps
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) anticorps
  • Akt anticorps
  • CADTK anticorps
  • CAKB anticorps
  • CAKbeta anticorps
  • E430023O05Rik anticorps
  • FADK2 anticorps
  • FAK2 anticorps
  • PKB anticorps
  • PKB/Akt anticorps
  • PKBalpha anticorps
  • PTK anticorps
  • Pyk2 anticorps
  • Rac anticorps
  • Raftk anticorps

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
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