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Mouse (Murine) CD44 Kit ELISA pour Sandwich ELISA - ABIN457122
Campo, Avenoso, DAscola, Prestipino, Scuruchi, Nastasi, Calatroni, Campo: Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. dans Archives of biochemistry and biophysics 2012
Show all 5 Pubmed References
Human CD44 Kit ELISA pour Sandwich ELISA - ABIN2859264
Li, Chu, Gao, Li: Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin. dans Acta biochimica et biophysica Sinica 2009
pERK1/2 is a regulator of CD44 expression, and increased CD44 expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
MET signaling regulates intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10.
study demonstrates that CD44 plays a critical role in the regulation of experimental autoimmune encephalomyelitis through alterations in the gut microbiome profile and short-chain fatty acid production
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
OA/GPNMB acts through ERK (Montrer EPHB2 Kits ELISA) and AKT (Montrer AKT1 Kits ELISA) signaling pathways in mesenchymal stem cells via CD44
These findings support the usefulness of the conditional Cd44 allele in unraveling essential physiological and pathological functions of CD44 isoforms.
CD44 role in the atrophic epidermis
CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.
CD44V6 is part of a positive-feedback loop with TGFbeta1 (Montrer TGFB1 Kits ELISA)/TGFbetaRI signaling that acts to increase NOX4 (Montrer NOX4 Kits ELISA)/ROS (Montrer ROS1 Kits ELISA) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.
HAS2 (Montrer HAS2 Kits ELISA)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (Montrer MAPK3 Kits ELISA)/EGR1 (Montrer EGR1 Kits ELISA) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (Montrer TGFB1 Kits ELISA)-stimulated CD44V6/ERK (Montrer EPHB2 Kits ELISA)/EGR1 (Montrer EGR1 Kits ELISA) signaling.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (Montrer CD14 Kits ELISA)-negative isolation yields an enhanced cell population SFB (Montrer CEBPB Kits ELISA) that is more potent than MSCP (Montrer SLC25A37 Kits ELISA) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
suggest that upregulation of NG2/CSPG4 (Montrer MCSP Kits ELISA) rather than changes in CD44 or Ki-67 (Montrer MKI67 Kits ELISA) expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 (Montrer MCSP Kits ELISA) as a potential prognostic marker in glioblastoma
Suggest that CD44-positivity might be a candidate tumor stem cell marker in intrahepatic cholangiocarcinoma and a prognostic indicator.
Mechanistically, CD44v interacts with and stabilizes xCT (Montrer SLC7A11 Kits ELISA) and thereby promotes the uptake of cysteine for glutathione synthesis and stimulates side-population cell enrichment.
These tumor samples express CD44 protein at low rather than high levels. There is no correlation between CLDN3 (Montrer CLDN3 Kits ELISA) gene expression and protein expression in these CPTAC samples; hence, the claudin-low subtype defined by gene expression is not the same group of tumors as that defined by low expression of CLDN3 (Montrer CLDN3 Kits ELISA) protein.
this study shows that genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1 (Montrer PKD1 Kits ELISA)/NF-kappaB (Montrer NFKB1 Kits ELISA) signaling pathway
High CD44 expression is associated with high grade glioma.
CNS disease was associated with enhanced expression of cytoplasmic and membranous ITGA10 and nuclear PTEN (P < 0.0005, P = 0.002, P = 0.024, respectively). sCNSL presented decreased membranous CD44 and nuclear and cytoplasmic cadherin-11 expressions (P = 0.001, P = 0.006, P = 0.048, respectively). In PCNSL lactoferrin (Montrer LTF Kits ELISA) expression was upregulated (P < 0.0005).
In clinical specimens of breast cancer, authors established that the expression of CD44s and HAS2 (Montrer HAS2 Kits ELISA) was positively correlated. Results establish a positive feedback mechanism that sustains PI3K (Montrer PIK3CA Kits ELISA)/Akt (Montrer AKT1 Kits ELISA) signaling in tumor cells, further illuminating the nearly universal role of this pathway in cancer cell survival.
In regulation of tumour cells with high CD44 expression.
ZEB1 (Montrer ZEB1 Kits ELISA)-induced epithelial-to-mesenchymal transition and associated molecular changes in ESRP1 (Montrer ESRP1 Kits ELISA) and CD44 contribute to early pathogenesis and metastatic potential in established lung cancer
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (Montrer HYAL2 Kits ELISA).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (Montrer IL2RA Kits ELISA), CD44, and CD62L (Montrer SELL Kits ELISA) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (Montrer HMMR Kits ELISA)-mediated signalling pathways involving Cdc2 (Montrer CDK1 Kits ELISA) and gamma-adducin (Montrer ADD3 Kits ELISA).
The novel finding that TSP-1 (Montrer THBS1 Kits ELISA)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (Montrer THBS1 Kits ELISA) and HyA (Montrer KDM5D Kits ELISA)).
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, extracellular matrix receptor III
, hermes antigen
, hyaluronate receptor
, lymphocyte antigen 24
, phagocytic glycoprotein 1
, phagocytic glycoprotein I
, CD44 antigen
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, extracellular matrix receptor-III
, CD44-like protein
, lymphocyte surface antigen precursor CD44
, syndecan 4 (amphiglycan, ryudocan)