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anti-Rat (Rattus) CDX2 Anticorps:
anti-Human CDX2 Anticorps:
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Human Monoclonal CDX2 Primary Antibody pour BI, WB - ABIN967663
Hinoi, Loda, Fearon: Silencing of CDX2 expression in colon cancer via a dominant repression pathway. dans The Journal of biological chemistry 2003
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Human Polyclonal CDX2 Primary Antibody pour IHC (p), IP - ABIN151575
Verzi, Hatzis, Sulahian, Philips, Schuijers, Shin, Freed, Lynch, Dang, Brown, Clevers, Liu, Shivdasani: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. dans Proceedings of the National Academy of Sciences of the United States of America 2010
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Human Monoclonal CDX2 Primary Antibody pour ELISA, WB - ABIN1724918
Lee, Vogt, Hsiao, Osunkoya: CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules. dans Tumour biology 2012
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Human Monoclonal CDX2 Primary Antibody pour FACS, ELISA - ABIN1724921
Liu, Zhang, Zhan, Brock, Herman, Guo: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. dans Cancer biology & therapy 2012
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Human Polyclonal CDX2 Primary Antibody pour ELISA, WB - ABIN251330
Qualtrough, Hinoi, Fearon, Paraskeva: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. dans Gut 2002
Cow (Bovine) Polyclonal CDX2 Primary Antibody pour WB - ABIN2777319
Saad, Cho, Silverman, Liu: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. dans American journal of clinical pathology 2004
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Human Monoclonal CDX2 Primary Antibody pour ELISA, WB - ABIN560320
Zulueta, Caretti, Signorelli, Dallolio, Trinchera: Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
Human Monoclonal CDX2 Primary Antibody pour IHC (p), IHC - ABIN152122
Flisikowska, Merkl, Landmann, Eser, Rezaei, Cui, Kurome, Zakhartchenko, Kessler, Wieland, Rottmann, Schmid, Schneider, Kind, Wolf, Saur, Schnieke: A porcine model of familial adenomatous polyposis. dans Gastroenterology 2012
These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.
our findings demonstrated that MDR1 (Montrer TBC1D9 Anticorps) expression is regulated by CDX2 and is related to drug resistance in ovarian mucinous adenocarcinoma.
The data presented provide a novel insight into how CDX2 is implicated in the transcriptional regulation of LAMC2 (Montrer LAMC2 Anticorps) in intestinal epithelial cells, a function that is impaired during mucosal inflammation where a high level of TNF-alpha (Montrer TNF Anticorps) is present.
Cytapheresis might induce CDX2 expression without affecting the cell proliferation, thus resulting in mucosal healing with goblet cell restoration.
SOX2 (Montrer SOX2 Anticorps) expression induces a cellular stem cell state in human colorectal cancer (CRC (Montrer CALR Anticorps)) with a decreased expression of CDX2. Furthermore, a down-regulated expression of CDX2 results in a poor patient prognosis in CRC (Montrer CALR Anticorps).
A small subset (5%) of hepatocellular carcinomas are CDX2 positive.
A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (Montrer HNF4A Anticorps) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (Montrer HNF4A Anticorps) in human biopsy samples.
Colon cancer cells expressing CDX2 are less deformable, a feature that has been shown to correlate with poor metastatic potential.
Results show that CDX2 and Fbw7 (Montrer FBXW7 Anticorps) expression is inversely correlated during colon cell differentiation and that CDX2 expression is regulated by Fbw7 (Montrer FBXW7 Anticorps) in a GSK3b (Montrer GSK3b Anticorps)-dependent manner.
Aberrant DNA methylation (Montrer HELLS Anticorps) of SOX2 (Montrer SOX2 Anticorps) and CDX2 genes contributes to the development of IM. Notably, SOX2 (Montrer SOX2 Anticorps) may play a role in establishing and maintaining the methylation status of the CDX2 gene in gastric tissues and cells.
Strong expression of CDX2 was demonstrated only in the mature colonic epithelium of teratomas in both primary and metastatic germ cell tumors of the testis.
these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.
showed novel molecular regulation of CDX2 on Oct4 (Montrer POU5F1 Anticorps), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (Montrer POU5F1 Anticorps) in embryo of mammals other than mouse
including Wnt (Montrer WNT2 Anticorps) and Fgf pathway components active in the axial progenitor niche. Our data demonstrate that integration of the Cdx (Montrer CDX1 Anticorps)/Hox (Montrer MSH2 Anticorps) and T Brachyury (Montrer TBX1 Anticorps) transcriptional networks controls differential axial growth during vertebrate trunk elongation
Cdx (Montrer CDX1 Anticorps) members interact with the SWI (Montrer SMARCA1 Anticorps)-SNF (Montrer SNRPA Anticorps) complex and make direct contact with Brg1 (Montrer SMARCA4 Anticorps), a catalytic member of SWI (Montrer SMARCA1 Anticorps)-SNF (Montrer SNRPA Anticorps). Both Cdx2 and Brg1 (Montrer SMARCA4 Anticorps) co-occupy a number of Cdx (Montrer CDX1 Anticorps) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (Montrer SMARCA4 Anticorps) occupancy occurs coincident with chromatin remodeling at some of these loci.
The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (Montrer MSH2 Anticorps) gene.
Cdx1 (Montrer CDX1 Anticorps)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (Montrer ADCY10 Anticorps) and a block in hematopoietic differentiation from yolk sac (Montrer ADCY10 Anticorps)-derived cells in culture.
this study shows that Aloe vera (Montrer IGF2BP3 Anticorps) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer
Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (Montrer HOXB7 Anticorps) and Cdx2 in colon cancer cells.
CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (Montrer NFS1 Anticorps) may be activated or repressed.
cells in preimplantation embryos that localized in an initial outer position initiated the expression of Cdx2. cells that changed their position from an outer to an inner position downregulated Cdx2 expression and contributed to the inner cell mass.
findings illuminated a role for NOD1 (Montrer NOD1 Anticorps) signaling in attenuating H. pylori-induced Cdx2 expression in gastric epithelial cells
results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
caudal type homeobox 2
, caudal type homeobox transcription factor 2
, caudal type homeo box transcription factor 2
, homeobox protein CDX-2
, caudal-type homeobox protein 2
, caudal type homeo box 2
, caudal-type homeobox transcription factor 2