E3 ubiquitin-protein ligase RAD18 (RAD18) (Middle Region) Peptide
RAD18
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RAD18
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LSDRDLKKKL KEHGLSIQGN KQQLIKRHQE FVHMYNAQCD ALHPKSAAEI
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RAD18 Antibody(ARP43267_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Synonymes
- RNF73 Peptide, 2810024C04Rik Peptide, Rad18sc Peptide, zgc:55577 Peptide, RAD18 Peptide, DDBDRAFT_0218120 Peptide, DDBDRAFT_0304878 Peptide, DDB_0218120 Peptide, DDB_0304878 Peptide, DKFZp469H0810 Peptide, RAD18, E3 ubiquitin protein ligase Peptide, RAD18 E3 ubiquitin protein ligase Peptide, E3 ubiquitin-protein ligase RAD18 Peptide, E3 ubiquitin-protein ligase Peptide, DNA repair protein and ATPase Peptide, C3HC4-type zinc finger-containing protein Peptide, RAD18 Peptide, Rad18 Peptide, rad18 Peptide
- Sujet
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RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Alias Symbols: RNF73
Protein Interaction Partner: RAD18,UBE2A,UBE2B,HLTF,POLH,POLK,RAD51,SRRM2,TP53BP1,TSG101,UBE2A,UBE2B,UBE2I
Protein Size: 495 - Poids moléculaire
- 56 kDa
- ID gène
- 56852
- NCBI Accession
- NM_020165, NP_064550
- UniProt
- Q9NS91
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