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Human Aryl Hydrocarbon Receptor Kit ELISA pour Sandwich ELISA - ABIN414628
Kajta, Litwa, Rzemieniec, Wnuk, Lason, Zelek-Molik, Nalepa, Grzegorzewska-Hiczwa, Tokarski, Golas, Guzik, Grochowalski, Szychowski, Wojtowicz: Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling in apoptotic neuronal cells. dans Molecular and cellular endocrinology 2014
Identified structural features of AHR1beta associated with low TCDD sensitivity. Substitution of the entire ligand binding domain with the corresponding sequence from mouse AHR(b-1) dramatically increased TCDD responsiveness in transactivation assays.
Transient AHR activation and cytochrome P450 (Montrer CYP Kits ELISA) 1A (CYP1A) induction in livers occurred during ANIT-induced hepatobiliary impairment in medaka.
A low AHR-expression level in human lung cancer tissues is significantly associated with its malignancy.Cytoplasmic, resting AHR protein acts as an epithelial-mesenchymal transition suppressor via a non-genomic pathway.
Aryl hydrocarbon receptor signaling modifies Toll (Montrer TLR4 Kits ELISA)-like receptor-regulated responses in human dendritic cells.
These findings identify a role for pattern recognition receptor (PRR) signaling in regulating the AHR response through selective down-regulation of Cyp1 expression in human monocytes and macrophages.
The results of the present study suggest that AhR stimulates estrogen-dependent progression of breast carcinoma by inducing aromatase (Montrer CYP19A1 Kits ELISA) expression under some conditions. These results provide new insights on the possible roles of environmental toxins in breast cancer development.
AHR, CYP1A1 (Montrer CYP1A1 Kits ELISA), CYP1A2 (Montrer CYP1A2 Kits ELISA), or CYP1B1 (Montrer CYP1B1 Kits ELISA) variants associated with head-and-neck squamous cell carcinoma risk in smokers.
Low AHR expression is associated with Prostate Cancer.
activation of the aryl hydrocarbon receptor using the non-toxic agonist 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) induces human regulatory t cells.
this study demonstrates a role for the AHR in regulating human B cell development, and it suggests that transcriptional alterations of EBF1 (Montrer EBF1 Kits ELISA) by the AHR are involved in the underlying mechanism
These results establish that mo-DCs and mo-Macs are controlled by distinct transcription factors and show that AHR acts as a molecular switch for monocyte fate specification in response to micro-environmental factors.
Carbidopa is an AhR agonist and suppresses pancreatic cancer. Hence, Carbidopa could potentially be re-purposed to treat pancreatic cancer and possibly other cancers as well.
steroid hormones, AhR and estrogen receptor beta (Montrer ESR2 Kits ELISA) are affected by TCDD and genistein in granulosa cells of medium porcine follicles
AHR mRNA expression in follicular, theca, and granulosa cells suggest the involvement of AHR in the modulation of reproductive processes in the porcine ovary.
the untimely expression of the Ahr gene needs to be repressed to maintain embryonic stem cell mitotic progression and prevent premature loss of pluripotency.
The results suggest AhR activation causes the loss of liver-specific and sexually dimorphic gene expression producing a functionally "de-differentiated" hepatic phenotype.
Study provides evidence supporting the importance of AHR in tumor progression and host survival through the upregulation of ISX (Montrer ISX Kits ELISA) expression and promotion of tumor cell growth while restraining the expression of tumor suppressors in hepatocellular carcinoma (HCC (Montrer FAM126A Kits ELISA)), and thereby suggests a plausible mechanistic link between AHR and HCC (Montrer FAM126A Kits ELISA).
AhR controls COX-2 (Montrer COX2 Kits ELISA) protein via mRNA stability.
functional AhR expression is critical for skin barrier integrity and that AhR represents a molecular target for the development of therapeutic approaches for skin barrier diseases, including by dietary intervention.
Lipopolysaccharide (LPS (Montrer TLR4 Kits ELISA)) stimulation increased the expression and activity of the immunoregulatory enzyme IDO1 (Montrer IDO1 Kits ELISA) in hepatic stellate cells (HSCs), and LPS (Montrer TLR4 Kits ELISA)/HSCs stimulated aryl hydrocarbon receptor (AhR) signaling in cocultured regulatory T cells.
Donor T cells lacking AhR demonstrate decreased acute graft versus host disease because of reduced donor T-cell proliferation early after transplant.
this study shows that AhR-/- mice display impaired bone healing with delayed endochondral ossification
AhR(-/-) mice are not able to mount an Natural killer cell memory response to hapten rechallenge.
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
aryl hydrocarbon receptor
, aryl hydrocarbon receptor 1
, aryl hydrocarbon receptor-like
, ah receptor
, aromatic hydrocarbon receptor
, class E basic helix-loop-helix protein 76
, Ah receptor
, dioxin receptor