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Aperçu des produits pour anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Anticorps

Full name:
anti-Sterol Regulatory Element Binding Transcription Factor 2 Anticorps (SREBF2)
Chez www.anticorps-enligne.fr sont 90 Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions Sterol Regulatory Element Binding Transcription Factor 2 Protéines (10) et Sterol Regulatory Element Binding Transcription Factor 2 Kits (7) et beaucoup plus de produits pour cette protéine. Un total de 113 Sterol Regulatory Element Binding Transcription Factor 2 produits sont actuellement listés.
Synonymes:
AI608257, bHLHd2, lop13, nuc, SREBF2, Srebf2_retired, SREBP-2, SREBP2, SREBP2gc, zgc:158371

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anti-Sterol Regulatory Element Binding Transcription Factor 2 Anticorps mieux référencés

  1. Chicken Monoclonal SREBF2 Primary Antibody pour ELISA, GS - ABIN4355936 : Janowski, Shan, Russell: The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. dans The Journal of biological chemistry 2001 (PubMed)
    Show all 14 references for ABIN4355936

  2. Human Polyclonal SREBF2 Primary Antibody pour ICC, IF - ABIN261631 : Huster, Purnat, Burkhead, Ralle, Fiehn, Stuckert, Olson, Teupser, Lutsenko: High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. dans The Journal of biological chemistry 2007 (PubMed)
    Show all 6 references for ABIN261631

  3. Human Polyclonal SREBF2 Primary Antibody pour EIA, IF - ABIN954950 : Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN954950

  4. Human Monoclonal SREBF2 Primary Antibody pour IP, WB - ABIN967564 : Hua, Sakai, Ho, Goldstein, Brown: Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN967564

  5. Human Polyclonal SREBF2 Primary Antibody pour IF, IHC (p) - ABIN654630 : Marquart, Allen, Ory, Baldán: miR-33 links SREBP-2 induction to repression of sterol transporters. dans Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN654630

  6. Human Monoclonal SREBF2 Primary Antibody pour ChIP, WB - ABIN2668815 : Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment. dans PLoS ONE 2014 (PubMed)

  7. Human Polyclonal SREBF2 Primary Antibody pour IP, WB - ABIN4355938 : Karanth, Tran, Kuberan, Schlegel: Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice. dans Disease models & mechanisms 2013 (PubMed)

  8. Chicken Polyclonal SREBF2 Primary Antibody pour WB - ABIN2792226 : Zeng, Liao, Liu, Lee, Zhu, Wang, Stemerman, Zhu, Shyy: Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. dans The Journal of biological chemistry 2004 (PubMed)

Plus d’anticorps contre Sterol Regulatory Element Binding Transcription Factor 2 partenaires d’interaction

Mouse (Murine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. SIRT1 (Montrer SIRT1 Anticorps) gene knock-out may aggravate cartilage degeneration in osteoarthritis by activating the SREBP2 protein-mediated PI3K/AKT (Montrer AKT1 Anticorps) signalling pathway, suggesting that SIRT1 (Montrer SIRT1 Anticorps) gene may play a protective role against osteoarthritis.

  2. SREBP-2 is critical for survival and limb patterning during development

  3. Identify a novel signaling pathway in hepatocytes triggered by ligand-activated p75NTR (Montrer NGFR Anticorps) that via p38 MAPK (Montrer MAPK14 Anticorps) and caspase-3 (Montrer CASP3 Anticorps) mediate the activation of SREBP2. This pathway may regulate LDLRs and lipid uptake particularly after injury or during tissue inflammation accompanied by an increased production of growth factors, including NGF (Montrer NGFB Anticorps) and pro-NGF (Montrer NGFB Anticorps).

  4. This study reveals SHP (Montrer LAMC1 Anticorps) as a global transcriptional partner of SREBP-2 in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (Montrer FGF19 Anticorps).

  5. activation of the sterol regulatory element binding protein-2 (SREBP2) was found to be downstream of ER stress, and this activation was affirmed to account for the intracellular accumulation of cholesterol using RNAi technique

  6. ITCH modulates SIRT6 (Montrer SIRT6 Anticorps) and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE (Montrer APOE Anticorps) null mice

  7. SREBP2-induced miR (Montrer MLXIP Anticorps)-92a targets key molecules in endothelial homeostasis, including sirtuin 1 (Montrer SIRT1 Anticorps), Kruppel-like factor 2, and Kruppel-like factor 4 (Montrer KLF4 Anticorps), leading to NOD-like receptor family pyrin domain-containing 3 inflammasome activation and endothelial nitric oxide synthase (Montrer NOS3 Anticorps) inhibition.

  8. The cholesterol-lowering effects of FGF21 (Montrer FGF21 Anticorps) are abrogated by hepatic expression of sterol regulatory element-binding protein-2.

  9. Data indicate that Leishmania exploits macrophage cholesterol-dependent sterol regulatory element binding factor 2 (SREBP2) circuit to facilitate its entry and survival within the host.

  10. Demonstrate that the activation of FXR (Montrer NR1H4 Anticorps) uncouples the expression of nuclear SREBP-2 and miR (Montrer MLXIP Anticorps)-33, and the regulation of their respective target genes.

Human Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells.

  2. Identify a novel signaling pathway in hepatocytes triggered by ligand-activated p75NTR (Montrer NGFR Anticorps) that via p38 MAPK (Montrer MAPK14 Anticorps) and caspase-3 (Montrer CASP3 Anticorps) mediate the activation of SREBP2. This pathway may regulate LDLRs and lipid uptake particularly after injury or during tissue inflammation accompanied by an increased production of growth factors, including NGF (Montrer NGFB Anticorps) and pro-NGF (Montrer NGFB Anticorps).

  3. Data show that mutant p53 protein (Montrer TP53 Anticorps) activates the sterol regulatory element-binding proteins SREBP-1 (Montrer SREBF1 Anticorps) and SREBP-2-mediated signaling pathways in prostate cancer (PCa (Montrer FLVCR1 Anticorps)) cells.

  4. The connections of EGFR (Montrer EGFR Anticorps) and ERBB4 (Montrer ERBB4 Anticorps) signaling with SREBP-2-regulated cholesterol metabolism are likely to be important in ERBB (Montrer EGFR Anticorps)-regulated developmental processes and may contribute to metabolic remodeling in ERBB (Montrer EGFR Anticorps)-driven cancers.

  5. Akt1 (Montrer AKT1 Anticorps) and Akt2 (Montrer AKT2 Anticorps) activated both SREBP-1 (Montrer SREBF1 Anticorps) and SREBP-2, whereas Akt3 (Montrer AKT3 Anticorps) upregulated SREBP-1 (Montrer SREBF1 Anticorps) to enhance hepatitis C virus translation.

  6. knockdown of endogenous SREBP2 in HepG2 cells lowered ACSL1 (Montrer Acsl1 Anticorps) mRNA and protein levels.

  7. Data suggest that Hepacivirus (HCV) activates hepatocyte NLRP3 (Montrer NLRP3 Anticorps) inflammasomes, induces lipogenic enzymes/lipid droplet formation, and up-regulates transport of SREBF1 (Montrer SREBF1 Anticorps)/SREBF2/SCAP (Montrer SH2D2A Anticorps) from ER to Golgi where SREBPs undergo proteolytic activation by S1P (Montrer MBTPS1 Anticorps)/S2P (Montrer MBTPS2 Anticorps).

  8. Data suggest lysophosphatidylcholine (LPC (Montrer PCSK7 Anticorps)) up-regulates SREBP-2 and cholesterol efflux in vascular endothelium; 25-hydroxycholesterol (25-HC) inhibits these effects of LPC (Montrer PCSK7 Anticorps); both LPC (Montrer PCSK7 Anticorps) and 25-HC up-regulate release of interleukin-6 (Montrer IL6 Anticorps) and interleukin-8 (Montrer IL8 Anticorps).

  9. the results of the present study showed that luteolin modulates HMGCR (Montrer HMGCR Anticorps) transcription by decreasing the expression and nuclear translocation of SREBP-2.

  10. performed a detailed promoter/enhancer analysis of ELOVL5 (Montrer ELOVL5 Anticorps) gene, and identified two new SREBP binding sites, one in the 10 kb upstream region and one in the exon 1

Pig (Porcine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. dysregulation of SIRT1 (Montrer SIRT1 Anticorps)-AMPK (Montrer PRKAA1 Anticorps)-SREBP and stimulation of NLRP3 (Montrer NLRP3 Anticorps) inflammasome may contribute to vascular lipid deposition and inflammation in atherosclerosis

  2. KLF13 (Montrer KLF13 Anticorps) and SREBP-Sp1 (Montrer SP1 Anticorps) activation interact to regulate low density lipoprotein receptor (Montrer LDLR Anticorps) promoter function

Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) profil antigène

Antigen Summary

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Alternative names and synonyms associated with Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2)

  • sterol regulatory element binding transcription factor 2 (SREBF2) anticorps
  • sterol regulatory element binding transcription factor 2 (srebf2) anticorps
  • sterol regulatory element binding protein 2 (SREBP2) anticorps
  • sterol regulatory element binding factor 2 (Srebf2) anticorps
  • sterol regulatory element binding protein-2 (SREBP-2) anticorps
  • sterol regulatory element binding transcription factor 2 (Srebf2) anticorps
  • AI608257 anticorps
  • bHLHd2 anticorps
  • lop13 anticorps
  • nuc anticorps
  • SREBF2 anticorps
  • Srebf2_retired anticorps
  • SREBP-2 anticorps
  • SREBP2 anticorps
  • SREBP2gc anticorps
  • zgc:158371 anticorps

Protein level used designations for SREBF2

sterol regulatory element binding transcription factor 2 , sterol regulatory element-binding protein 2-like , sterol regulatory element binding protein 2 , SREBP-2 , sterol regulatory element-binding protein 2 , sterol regulatory element-binding transcription factor 2 , class D basic helix-loop-helix protein 2 , sterol regulatory element binding factor 2

GENE ID SPECIES
712307 Macaca mulatta
100070704 Equus caballus
100144677 Xenopus (Silurana) tropicalis
100480211 Ailuropoda melanoleuca
100552463 Anolis carolinensis
100124292 Monodelphis domestica
507102 Bos taurus
100037309 Danio rerio
100502557 Salmo salar
20788 Mus musculus
100008783 Oryctolagus cuniculus
443980 Xenopus laevis
395304 Gallus gallus
6721 Homo sapiens
481228 Canis lupus familiaris
396675 Sus scrofa
300095 Rattus norvegicus
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