Aperçu des produits pour anti-MAP2K4 (MAP2K4) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 4 Anticorps (MAP2K4)
Chez www.anticorps-enligne.fr sont 322 Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions MAP2K4 Protéines (10) et MAP2K4 Kits (8) et beaucoup plus de produits pour cette protéine. Un total de 359 MAP2K4 produits sont actuellement listés.
Synonymes:
2, 142758_at, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, ATMEK4, ATMKK4, CG9738, CT27508, CT38386, D-MKK4, DmelCG12798, Dmel\\CG9738, dMkk4, F19C24.26, F19C24_26, hep, JNKK, JNKK1, Jnkk2, map2k4, MAP KINASE KINASE 4, MAPKK4, Mapkk7, MEK4, Mek7, mitogen-activated protein kinase kinase 4, MKK4, MKK4A-l, Mkk7, Mpk4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SEK1/MKK4, Serk1, SKK1, xmek2, zgc:136500
afficher tous les anticorps Gène GeneID UniProt
MAP2K4 287398  
MAP2K4 6416 P45985
MAP2K4 26398 P47809

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anti-Rat (Rattus) MAP2K4 Anticorps:

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anti-MAP2K4 Anticorps mieux référencés

  1. Human Polyclonal MAP2K4 Primary Antibody pour IHC, ELISA - ABIN1531968 : Lin, Minden, Martinetto, Claret, Lange-Carter, Mercurio, Johnson, Karin: Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. dans Science (New York, N.Y.) 1995 (PubMed)
    Show all 2 references for 1531968

  2. Human Polyclonal MAP2K4 Primary Antibody pour IF, IHC (p) - ABIN197322 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. dans Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for 197322

  3. Human Monoclonal MAP2K4 Primary Antibody pour FACS, IHC - ABIN969268 : Song, Coffa, Fu, Gurevich: How does arrestin assemble MAPKs into a signaling complex? dans The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for 969268

  4. Human Polyclonal MAP2K4 Primary Antibody pour IHC (p), WB - ABIN658838 : Finegan, Tournier: The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer. dans Cancer research 2010 (PubMed)
    Show all 2 references for 658838

  5. Human Polyclonal MAP2K4 Primary Antibody pour ELISA, WB - ABIN1533737 : Dérijard, Raingeaud, Barrett, Wu, Han, Ulevitch, Davis: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. dans Science (New York, N.Y.) 1995 (PubMed)
    Show all 2 references for 1533737

  6. Human Polyclonal MAP2K4 Primary Antibody pour IF, IHC (p) - ABIN196908 : Leung, Lassam: The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation. dans The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for 196908

  7. Human Polyclonal MAP2K4 Primary Antibody pour IF, IHC (p) - ABIN196910 : Park, Kim, Huh, Park, Chung, Kang, Choi: Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. dans The Journal of biological chemistry 2002 (PubMed)

Plus d’anticorps contre MAP2K4 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. in Drosophila both MAPKKs, Hep/Mkk7 (Montrer MAP2K7 Anticorps) and Mkk4, are required to induce JNK (Montrer MAPK8 Anticorps) upon TNF (Montrer TNF Anticorps) or pro-inflammatory stimulation

Human Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. MKK4 activates non-canonical NFkappaB (Montrer NFKB1 Anticorps) signaling by promoting NFkappaB2-p100 (Montrer CUX1 Anticorps) processing.

  2. Manipulating the expression of both miR (Montrer MLXIP Anticorps)-222 and miR (Montrer MLXIP Anticorps)-25 influenced diverse gene expression changes in thyroid cells. Increased expression of miR (Montrer MLXIP Anticorps)-25 reduced MEK4 and TRAIL protein expression, and cell adhesion and apoptosis are important aspects of miR (Montrer MLXIP Anticorps)-25 functioning in thyroid cells.

  3. These results suggest that ROCK may be important in IL-1 (Montrer IL1A Anticorps)-induced signaling through MKK4 to JNK (Montrer MAPK8 Anticorps) and the activation of p38 MAPK (Montrer MAPK14 Anticorps).

  4. Association between MKK4 promoter polymorphism and breast cancer risk in Kashmiri population

  5. In Chinese Han ischemic stroke patients rs3826392 C/A genotype carriers showed significantly higher IL-1b (Montrer IL1B Anticorps) serum levels.

  6. The plasma level of protein MAP2K4 was found to suggestively associate negatively with the volume of the left entorhinal cortex in asymptomatic older twins.

  7. MAP2K4 increases human prostate cancer metastasis, and prolonged over expression induces long term changes in cell signaling pathways leading to independence from p38 MAPK (Montrer MAPK14 Anticorps) and JNK (Montrer MAPK8 Anticorps).

  8. MKK4 is activated in vitro by reduced Trx (Montrer VAC14 Anticorps) but not oxidized Trx (Montrer VAC14 Anticorps) in the absence of an upstream kinase, suggesting that autophosphorylation of this protein occurs due to reduction of Cys (Montrer DNAJC5 Anticorps)-246 and Cys (Montrer DNAJC5 Anticorps)-266 by Trx (Montrer VAC14 Anticorps).

  9. Data suggest a genetic interaction between MAP2K4 and HLA-DRB1 (Montrer HLA-DRB1 Anticorps), and the importance of rs10468473 and MAP2K4 splice variants in the development of autoantibody-positive RA.

  10. knockdown of Sec8 (Montrer EXOC4 Anticorps) enhances the binding of JIP4 (Montrer SPAG9 Anticorps) to MAPK (Montrer MAPK1 Anticorps) kinase 4, thereby decreasing the phosphorylation of MAPK (Montrer MAPK1 Anticorps) kinase 4, JNK (Montrer MAPK8 Anticorps), and p38 (Montrer CRK Anticorps).

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. MKK4 activates non-canonical NFkappaB signaling by promoting NFkappaB2-p100 (Montrer PATL2 Anticorps) processing.

  2. Demonstrate that Mkk4 is a negative regulator of the TGF-beta1 (Montrer TGFB1 Anticorps) signaling associated with atrial remodeling and arrhythmogenesis with age.

  3. This study provides compelling evidence for the pivotal roles of the ZPK/DLK (Montrer MAP3K12 Anticorps) and MKK4/MAP2K4-dependent mechanism in axotomy-induced motoneuron death in neonates.

  4. The loss of mkk4 and mkk7 (Montrer MAP2K7 Anticorps) locks damaged exocrine cells in a permanently de-differentiated state.

  5. Studies identify the dual-specific kinase MKK4 as a master regulator of liver regeneration. MKK4 silencing robustly increased the regenerative capacity of hepatocytes in mouse models of liver regeneration and acute and chronic liver failure.

  6. MicroRNA-92a negatively regulates Toll (Montrer TLR4 Anticorps)-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase

  7. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.

  8. MKK4/7 and JNK1 (Montrer MAPK8 Anticorps)/2 played regulatory role in cytoskeleton reorganization during vaccinia virus infection.

  9. These data support a model in which MKK4 activation at the metastatic site causes a cell-cycle arrest.

  10. Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 (Montrer GJA1 Anticorps) reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. MKK4, MKK5 (Montrer MAP2K5 Anticorps), MKK7 (Montrer MAP2K7 Anticorps), and MKK9, are responsible for the activation of MPK3 (Montrer MAPK3 Anticorps) and MPK6 (Montrer MAPK6 Anticorps) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (Montrer MAPK1 Anticorps) signaling through MKK4/5/7/9-MPK3 (Montrer MAPK3 Anticorps)/6 cascades.

  2. our data indicate that EDR1 (Montrer PHC1 Anticorps) physically associates with MKK4/MKK5 (Montrer MAP2K5 Anticorps) and negatively regulates the MAPK (Montrer MAPK1 Anticorps) cascade to fine-tune plant innate immunity.

  3. Results suggest that the YDA-MKK4/MKK5 (Montrer MAP2K5 Anticorps)-MPK3 (Montrer MAPK3 Anticorps)/MPK6 (Montrer MAPK6 Anticorps) cascade functions downstream of the ER receptor in regulating localized cell proliferation, which further shapes the morphology of plant organs.

  4. MKK4 is involved in the osmotic-stress response via its regulation of MPK3 (Montrer MAPK3 Anticorps) activity.

  5. MKK4 is a key regulator of stomatal development and patterning.

MAP2K4 profil antigène

Antigen Summary

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.

Alternative names and synonyms associated with MAP2K4

  • mitogen-activated protein kinase kinase 4 (map2k4) anticorps
  • MAP kinase kinase 4 (Mkk4) anticorps
  • CG12798 (CG12798) anticorps
  • mitogen activated protein kinase kinase 4 (Map2k4) anticorps
  • mitogen activated protein kinase kinase 7 (Map2k7) anticorps
  • mitogen-activated protein kinase kinase 4 (MAP2K4) anticorps
  • mitogen-activated protein kinase kinase 4 (Map2k4) anticorps
  • mitogen-activated protein kinase kinase 4 (MKK4) anticorps
  • mitogen-activated protein kinase kinase 4a (map2k4a) anticorps
  • 2 anticorps
  • 142758_at anticorps
  • ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 anticorps
  • ATMEK4 anticorps
  • ATMKK4 anticorps
  • CG9738 anticorps
  • CT27508 anticorps
  • CT38386 anticorps
  • D-MKK4 anticorps
  • DmelCG12798 anticorps
  • Dmel\\CG9738 anticorps
  • dMkk4 anticorps
  • F19C24.26 anticorps
  • F19C24_26 anticorps
  • hep anticorps
  • JNKK anticorps
  • JNKK1 anticorps
  • Jnkk2 anticorps
  • map2k4 anticorps
  • MAP KINASE KINASE 4 anticorps
  • MAPKK4 anticorps
  • Mapkk7 anticorps
  • MEK4 anticorps
  • Mek7 anticorps
  • mitogen-activated protein kinase kinase 4 anticorps
  • MKK4 anticorps
  • MKK4A-l anticorps
  • Mkk7 anticorps
  • Mpk4 anticorps
  • PRKMK4 anticorps
  • SAPKK-1 anticorps
  • SAPKK1 anticorps
  • SEK1 anticorps
  • SEK1/MKK4 anticorps
  • Serk1 anticorps
  • SKK1 anticorps
  • xmek2 anticorps
  • zgc:136500 anticorps

Protein level used designations for MAP2K4

CG9738-PA , CG9738-PB , CG9738-PC , JNK kinase 2 , Map kinase kinase 4 , Mkk4-PA , Mkk4-PB , Mkk4-PC , drosophila MAP kinase kinase 4 , CG12798 , CG12798-PA , MAP2K4delta , SAPK/ERK kinase 1 , dual specificity mitogen-activated protein kinase kinase 4 , JNK-activating kinase 2 , JNKK 2 , MAP kinase kinase 7 , MAPK/ERK kinase 7 , MAPKK 7 , MEK 7 , c-Jun N-terminal kinase kinase 2 , dual specificity mitogen-activated protein kinase kinase 7 , JNK activating kinase 1 , JNK-activated kinase 1 , JNK-activating kinase 1 , MAP kinase kinase 4 , MAPK/ERK kinase 4 , MAPKK 4 , MEK 4 , c-Jun N-terminal kinase kinase 1 , stress-activated protein kinase kinase 1 , C-JUN N-terminal kinase kinase 1 , JNK kinase 1 , JNKK 1 , SAPK/Erk/kinase 1 , mitogen activated protein kinase kinase 4, variant 1 , mitogen-activated protein kinase kinase 4 , mkk4a

GENE ID SPECIES
100135013 Xenopus (Silurana) tropicalis
41020 Drosophila melanogaster
3355004 Drosophila melanogaster
287398 Rattus norvegicus
363855 Rattus norvegicus
6416 Homo sapiens
26398 Mus musculus
489508 Canis lupus familiaris
841591 Arabidopsis thaliana
403052 Danio rerio
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