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Aperçu des produits pour anti-ADAM10 (ADAM10) Anticorps

Full name:
anti-ADAM Metallopeptidase Domain 10 Anticorps (ADAM10)
Chez sont 142 ADAM Metallopeptidase Domain 10 (ADAM10) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions ADAM10 Kits (43) et ADAM10 Protéines (20) et beaucoup plus de produits pour cette protéine. Un total de 209 ADAM10 produits sont actuellement listés.
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
afficher tous les anticorps Gène GeneID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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anti-Mouse (Murine) ADAM10 Anticorps:

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anti-ADAM10 Anticorps mieux référencés

  1. Human Polyclonal ADAM10 Primary Antibody pour WB - ABIN264988 : Rosendahl, Ko, Long, Brewer, Rosenzweig, Hedl, Anderson, Pyle, Moreland, Meyers, Kohno, Lyons, Lichenstein: Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. dans The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for ABIN264988

  2. Cow (Bovine) Polyclonal ADAM10 Primary Antibody pour EIA, IF - ABIN401037 : Pan, Rubin: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. dans Cell 1997 (PubMed)
    Show all 4 references for ABIN401037

  3. Mouse (Murine) Monoclonal ADAM10 Primary Antibody pour FACS - ABIN4897869 : Doi, Imai, Kressler, Yagita, Agata, Vooijs, Hamazaki, Inoue, Minato: Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia. dans Scientific reports 2015 (PubMed)
    Show all 4 references for ABIN4897869

  4. Human Polyclonal ADAM10 Primary Antibody pour EIA, IF - ABIN499211 : Qi, Rand, Wu, Sestan, Wang, Rakic, Xu, Artavanis-Tsakonas: Processing of the notch ligand delta by the metalloprotease Kuzbanian. dans Science (New York, N.Y.) 1999 (PubMed)
    Show all 4 references for ABIN499211

  5. Mouse (Murine) Monoclonal ADAM10 Primary Antibody pour FACS - ABIN4897868 : Gibb, Saleem, Kang, Subler, Conrad: ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. dans Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 2 references for ABIN4897868

  6. Human Polyclonal ADAM10 Primary Antibody pour IF (p), IHC (p) - ABIN701020 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. dans Gene 2015 (PubMed)

  7. Human Monoclonal ADAM10 Primary Antibody pour FACS - ABIN4897866 : Nygaard, Pallister, Zurek, Voyich: The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300. dans Journal of leukocyte biology 2013 (PubMed)

Plus d’anticorps contre ADAM10 partenaires d’interaction

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. this study shows that during positive selection in the spleen, B-cell receptor signaling causes immature type 1 transitional B cells to become receptive to Notch (Montrer NOTCH1 Anticorps) ligands via Taok3 (Montrer TAOK3 Anticorps)-mediated surface expression of ADAM10

  2. Thus, Leda-1/Pianp (Montrer C12orf53 Anticorps) is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  3. ADAM10 was dispensable for alpha-toxin (Montrer PLC Anticorps)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (Montrer PLC Anticorps) attack on the plasma membrane was confirmed.

  4. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  5. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  6. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (Montrer NOTCH1 Anticorps) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (Montrer DCX Anticorps) expression

  7. our data afford the new insight that miR (Montrer MLXIP Anticorps)-103a inhibited abdominal aortic aneurysm (AAA (Montrer AAAS Anticorps)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (Montrer AAAS Anticorps).

  8. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

  9. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (Montrer AXL Anticorps)kinase (Axl) in lupus-prone leukocytes.

  10. Loss of ADAM10 in murine liver results in hepatocyte necrosis and concomitant liver fibrosis. ADAM10 directly regulates expression of bile acid transporters but is dispensable for Notch2 (Montrer NOTCH2 Anticorps)-dependent formation of the biliary system. Differentiation of liver progenitor cells to hepatocytes is augmented in the absence of ADAM10.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. 1,25D3 causes ectodomain shedding of TLR4 (Montrer TLR4 Anticorps) and thereby decreases the responsiveness of cells to LPS (Montrer IRF6 Anticorps). ADAM10, activated by extracellular Ca2 (Montrer CA2 Anticorps)+ influx, was implicated in the ectodomain cleavage of TLR4 (Montrer TLR4 Anticorps).

  2. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  3. Pre-incubation with simvastatin prior to treatment with IL-1beta (Montrer IL1B Anticorps) + Oncostatin M (Montrer OSM Anticorps) decreased the level of CD44 (Montrer CD44 Anticorps) fragmentation, decreased the proportion of CD44 (Montrer CD44 Anticorps) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (Montrer CD44 Anticorps) and ADAM10.

  4. ADAM17 (Montrer ADAM17 Anticorps) and ADAM10 cleave Nectin-4 (Montrer PVRL4 Anticorps) and release soluble Nectin-4 (Montrer PVRL4 Anticorps) (sN4).

  5. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (Montrer AXL Anticorps)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (Montrer ADAM17 Anticorps)) inhibition.

  6. we found that ADAM10 expression was associated with a more rapid metastatic progression confirming its role in uveal melanoma metastasis.

  7. the TLR4 (Montrer TLR4 Anticorps)/Gal-1 (Montrer LGALS1 Anticorps) signaling pathway regulates lactate-mediated EMT (Montrer ITK Anticorps) processes through the activation of ADAM10 and ADAM17 (Montrer ADAM17 Anticorps) in colon cancer cells.

  8. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (Montrer LRP1 Anticorps) in the brain and the clearance of Abeta (Montrer APP Anticorps) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (Montrer APP Anticorps) accumulation in the AD brain

  9. In response to trastuzumab, both HER3 (Montrer ERBB3 Anticorps) and the metalloprotease (Montrer ADAM8 Anticorps) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (Montrer ERBB3 Anticorps) ligand heregulin (Montrer NRG1 Anticorps) from the cell surface to activate HER3 (Montrer ERBB3 Anticorps) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (Montrer RYK Anticorps) signaling.

  10. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (Montrer CDH1 Anticorps) activity.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (Montrer EFNB2 Anticorps) protein levels on the absence of flotillin-1 (Montrer FLOT1 Anticorps) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (Montrer ADAM8 Anticorps) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (Montrer APLP2 Anticorps) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 profil antigène

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) anticorps
  • ADAM metallopeptidase domain 10 (ADAM10) anticorps
  • ADAM metallopeptidase domain 10 (LOC100219653) anticorps
  • ADAM metallopeptidase domain 10 (Adam10) anticorps
  • a disintegrin and metallopeptidase domain 10 (Adam10) anticorps
  • ADAM metallopeptidase domain 10 (adam10) anticorps
  • ADAM10 (LOC100101614) anticorps
  • 1700031C13Rik anticorps
  • ad10 anticorps
  • ADAM-10 anticorps
  • ADAM 10 anticorps
  • Adam10 anticorps
  • cd156c anticorps
  • HsT18717 anticorps
  • kuz anticorps
  • kuzbanian anticorps
  • LOC100219653 anticorps
  • madm anticorps
  • wu:fc03d12 anticorps
  • xadam10 anticorps

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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