ABCG8 Produits
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
Catégories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
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Catégories ABCG8 en vedette
ABCG8 Anticorps
High quality antibodies with extensive validation data.
ABCG8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ABCG8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (5)
N° du produit
ABIN3022643
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7144942
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN6259696
Quantité
100 μL
Fiche technique
Fiche technique
ABCG8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
N° du produit
ABIN3129570
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN3087977
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3118045
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ABCG8
: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." dans: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).: "Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function." dans: Cell death & disease, Vol. 9, Issue 2, pp. 173, (2019) (PubMed).
: "Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease." dans: The Korean journal of internal medicine, (2018) (PubMed).
: "On the regulatory importance of 27-hydroxycholesterol in mouse liver." dans: The Journal of steroid biochemistry and molecular biology, (2016) (PubMed).
: "Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism." dans: Biochimica et biophysica acta, Vol. 1861, Issue 9 Pt A, pp. 1132-41, (2016) (PubMed).
: "Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model." dans: Endocrinology, Vol. 156, Issue 12, pp. 4545-57, (2015) (PubMed).
: "Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice." dans: Journal of lipid research, Vol. 55, Issue 3, pp. 540-8, (2014) (PubMed).
: "Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter." dans: Scientific reports, Vol. 4, pp. 4258, (2014) (PubMed).
: "Lactobacillus acidophilus ATCC 4356 prevents atherosclerosis via inhibition of intestinal cholesterol absorption in apolipoprotein E-knockout mice." dans: Applied and environmental microbiology, Vol. 80, Issue 24, pp. 7496-504, (2014) (PubMed).
: "Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease." dans: Digestive diseases and sciences, Vol. 59, Issue 12, pp. 2975-82, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à ABCG8
ATP binding cassette subfamily G member 8 (ABCG8), ATP-binding cassette sub-family G member 8 (PTRG_02054), ABC transporter G family protein (abcG8), ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8), ATP binding cassette subfamily G member 8 (Abcg8), 1300003C16Rik, AI114946, DDBDRAFT_0167690, DDBDRAFT_0191232, DDB_0167690, DDB_0191232, GBD4, sterolin-2, STSL, zgc:172358Protein level used designations for ABCG8
- ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)
- sterolin 2
- ATP-binding cassette sub-family G member 8
- sterolin-2
- ATP-binding cassette, sub-family G (WHITE), member 8
- ATP-binding cassette sub-family G member 8-like
- ATP-binding cassette, subfamily G, member 8
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