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Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 Protéines (CYP2B6)

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions CYP2B6 Anticorps (54) et CYP2B6 Kits (11) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat CYP2B6 CYP2B6 286953 P13107
CYP2B6 1555 P20813
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Top CYP2B6 Protéines sur anticorps-enligne.fr

Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 57 Days
7.380,00 €
Détails
HOST_Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 8 to 9 Days
345,60 €
Détails
HOST_HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 6 to 8 Days
748,00 €
Détails

CYP2B6 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
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Plus protéines pour Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) partenaires d'interaction

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. It has been established that cytochrome P4502B6 (CYP2B6) is the major isoform catalyzing both ketamine N-demethylation and ketamine metabolism overall in vitro at therapeutic concentrations and clinically.

  2. polymorphism c.516G>T in the CYP2B6 gene and BMI affect the metabolism rate of propofol and may play an important role in the optimisation of propofol anaesthesia

  3. his cross-sectional, pharmacogenetic candidate, gene pilot study recruited 75 patients having minor elective outpatient surgeries. EP was measured with the Clinician Administered Dissociative State Scale. Genetic association of CYP2B6*6 and GRIN2B (Montrer GRIN2B Protéines) (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence and severity were tested using logistic and linear regression.

  4. Data suggest that A785G CYP2B6 gene polymorphisms and specific CYP2B6 haplotypes may be a risk factor for the pathogenesis of AML (Montrer RUNX1 Protéines), especially secondary AML (Montrer RUNX1 Protéines) as well as for the induction of AML (Montrer RUNX1 Protéines) chromosomal aberrations.

  5. Results show that CYP2B6 slow metabolizer genotypes were significantly associated with efavirenz induced central nervous system symptoms.

  6. The possible influence of CYP2B6 c.516G>T genetic variant on propofol dose.

  7. Around 450 and 250 mg daily doses might meet EFV dosing needs of HIV-TB infected Ugandans in general and CYP2B6*6/*6 genotypes, respectively.

  8. CYP2B6 polymorphisms were associated with lower and higher plasma concentrations in pregnant and postpartum women.

  9. Analysis of gene-gene interactions with CYP2B6 was particularly useful to reinforce the role of MRP4 and to reveal unknown associations, such as that of DRD3 (Montrer DRD3 Protéines).

  10. POR (Montrer POR Protéines) rs2868177 and CYP2B6*6 variants contribute to the interindividual variability in human CYP2B6 activity, which may affect the disposition and interaction of other CYP2B6 substrate drugs

Profil protéine CYP2B6

Profil protéine

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6)
  • cytochrome P450, family 2, subfamily B, polypeptide 6 (cyp2b6)
  • cytochrome P450 2B11 (CYP2B6)
  • cytochrome P450, family 2, subfamily b, polypeptide 3 (Cyp2b3)
  • CPB6 Protéine
  • CYP2B Protéine
  • Cyp2b6 Protéine
  • CYP2B7 Protéine
  • CYP2B7P Protéine
  • CYP2B11 Protéine
  • CYP2B30 Protéine
  • CYPIIB6 Protéine
  • CYPIIB11 Protéine
  • EFVM Protéine
  • IIB1 Protéine
  • P450 Protéine

Protein level used designations for CYP2B6

cytochrome P450 2B6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , CYPIIB3 , cytochrome P450 2B3 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450IIB3 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 IIB1

GENE ID SPECIES
678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
286953 Rattus norvegicus
1555 Homo sapiens
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