anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) Anticorps

CYP2C8 encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions CYP2C8 Protéines (3) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CYP2C8 1558 P10632
CYP2C8    
CYP2C8    
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Top anti-CYP2C8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 54 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human testis, using Cytochrome P450 2C8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher Disponible
$363.46
Détails
Humain Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué WB   200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of anti-CYP2C8 Antibody (N-term) (ABIN392529) in T47D cell line lysates (35 µg/lane). CYP2C8(arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Western Blot: Cytochrome P450 2C8 Antibody [NBP1-88054] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: Cytochrome P450 2C8 Antibody [NBP1-88054] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: Cytochrome P450 2C8 Antibody [NBP1-88055] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Immunohistochemistry-Paraffin: Cytochrome P450 2C8 Antibody  - Staining of human liver shows high expression. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué ELISA, IHC, WB ABIN6274646 at 1/100 staining Human cervical cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts from rat brain cells, using Cytochrome P450 2C8 Antibody.The lane on the left is treated with the antigen-specific peptide. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails

anti-CYP2C8 Anticorps mieux référencés

  1. Human Polyclonal CYP2C8 Primary Antibody pour ELISA, WB - ABIN4302095 : Leskelä, Jara, Leandro-García, Martínez, García-Donas, Hernando, Hurtado, Vicario, Montero-Conde, Landa, López-Jiménez, Cascón, Milne, Robledo, Rodríguez-Antona: Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity. dans The pharmacogenomics journal 2011 (PubMed)

Plus d’anticorps contre CYP2C8 partenaires d’interaction

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) interaction partners

  1. The effect of CKD on CYP1A2, CYP2C9, and CYP2C19 was variable and modest compared to CYP2C8 and OATP.

  2. Single Nucleotide Polymorphism in CYP2C8 , which synthesize epoxyeicosatrienoic acids, may modify Cardiovascular outcomes in Renal Transplant recipients.

  3. In the villous trophoblast, CYP2C8 was the most abundant protein. Its expression is higher than the CYP2C9 and CYP2J2 in the cytotrophoblast in the embryonic stage of development and remains higher in syncytiotrophoblast of term placenta.

  4. The present study confirms the variable distribution of CYP2C8 (*2 and *3) and CYP2C9 (*2 and *3) allelic polymorphisms among South Indian diabetic populations.

  5. We found that SNPs rs7909236 and rs1934953 of the CYP2C8 gene were significantly associated with increased risk of essential hypertension.

  6. Clopidogrel increases the exposure to pioglitazone by inhibiting its CYP2C8-mediated biotransformation.

  7. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6, ABCB1 and CYP2C8 associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  8. review summarizes glucuronides as CYP2C8 ligands and the active-site structural features of CYP2C8 that allow potential binding to glucuronides

  9. Preliminary results demonstrate SNPs in CYP2C8 represent potential genetic markers of coronary heart disease susceptibility.

  10. Inhibition of CYP2C8 activity adds to the protective effects of omega-3 LCPUFA on pathological retinal neovascularization and choroidal neovascularization.

  11. CYP2C8*3 carriers had an increased risk of peripheral neuropathy

  12. CYP2C8 Variants are associated with Ischemic Stroke.

  13. This review focuses on recent findings of in vitro studies on drug metabolizing activity of 3 highly polymorphic CYP2C members: CYP2C8, CYP2C9, and CYP2C19.

  14. CYP2C8*3 is a gain-of-function polymorphism for imatinib N-demethylation, which appears to be mainly mediated by CYP2C8 and not CYP3A4 in vitro in human liver microsomes

  15. CYP2C8 genetic polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations.

  16. CYP2C8-derived epoxyeicosatrienoic acids prevented TNF-alpha-induced HUVECs apoptosis via inhibition of oxidative stress associated with the Nrf2 signaling.

  17. Interaction among CYP2C8, EPHX2, and CYP4A11 Gene Variants Significantly Increases the Risk for Ischemic Stroke.

  18. These comprehensive findings could inform for further genotype-phenotype studies on interindividual differences in CYP2C8-mediated drug metabolism

  19. Significant gene-sex interaction for CYP2C8*3 with twofold increase in the relative risk of essential hypertension and a similar tendency for CYP2J2*7 associated with coronary artery disease without myocardial infarction in Bulgarian males.

  20. We did not observe any association of CYP2C8*2, CYP2C8*3, CYP2C9*2 and CYP2C9*3 with myocardial infarction

CYP2C8 profil antigène

Profil protéine

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene names and symbols associated with CYP2C8

  • cytochrome P450 family 2 subfamily C member 8 (CYP2C8) anticorps
  • Cytochrome P450 2C8 (CTN_0597) anticorps
  • cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8) anticorps
  • cytochrome P450 family 2 subfamily C member 8 S homeolog (cyp2c8.1.S) anticorps
  • cytochrome P450 family 2 subfamily C member 8 (cyp2c8.1) anticorps
  • cpc8 anticorps
  • cyp2c8 anticorps
  • CYP2C74 anticorps
  • cypiic8 anticorps
  • mp-12/mp-20 anticorps

Protein level used designations for CYP2C8

P450 form 1 , cytochrome P450 2C8 , cytochrome P450 IIC2 , cytochrome P450 MP-12 , cytochrome P450 MP-20 , cytochrome P450 form 1 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 , flavoprotein-linked monooxygenase , microsomal monooxygenase , s-mephenytoin 4-hydroxylase , xenobiotic monooxygenase , Cytochrome P450 2C8 , cytochrome P450 CYP2C74 , cytochrome P450, family 2, subfamily C, polypeptide 8

GENE ID SPECIES
1558 Homo sapiens
7378980 Thermotoga neapolitana DSM 4359
678683 Macaca mulatta
379297 Xenopus laevis
450909 Pan troglodytes
100127852 Xenopus (Silurana) tropicalis
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