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Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Protéines (CYP2E1)

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Anticorps (177) et Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Kits (42) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CYP2E1 1571 P05181
CYP2E1 13106 Q05421
CYP2E1 25086 P05182
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Top Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Protéines sur anticorps-enligne.fr

Showing 10 out of 22 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 57 Days
7.380,00 €
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 57 Days
7.380,00 €
Détails
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Connectez-vous pour afficher 9 to 12 Days
784,67 €
Détails
HOST_Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 8 to 9 Days
235,20 €
Détails
Levure Macaca fascicularis His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.104,45 €
Détails
Levure Mesocricetus auratus His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.231,90 €
Détails
Levure Macaca mulatta His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.231,90 €
Détails
Levure Lapin His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.231,90 €
Détails
Levure Chien His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.235,40 €
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 54 to 65 Days
3.237,14 €
Détails

CYP2E1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine) ,

Rat (Rattus) ,

Plus protéines pour Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) partenaires d'interaction

Rabbit Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. The localization of CYP1A2 (Montrer CYP1A2 Protéines), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98

Human Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. The CYP2E1-PPARalpha (Montrer PPARA Protéines) axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  2. Results demonstrated that CYP2E1*5B and CYP2E1*6 minor alleles play a role in the development of sporadic colorectal neoplasms.

  3. This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (Montrer SPINK1 Protéines) polymorphism; however, no association was found for the DraI polymorphism

  4. NS5A contributes to reactive oxygen species production by activating expression of NADPH (Montrer NQO1 Protéines) oxidases 1 and 4 as well as cytochrome P450 2E1.

  5. This meta-analysis suggests that the CYP2E1 polymorphisms contributed to the susceptibility of nasopharyngeal carcinoma, especially in Asian populations.

  6. Study indicate that ALDH2 (Montrer ALDH2 Protéines) Glu487Lys and CYP4502E1 polymorphisms could be risk factors for the development of gastric cancer in the Chinese population.

  7. genetic association studies in population in Italy: Data suggest that SNPs in CYP2E1 are associated with differentiated thyroid carcinoma.

  8. CYP2E1 RsaI/PstI (Montrer SPINK1 Protéines) polymorphisms may modify the susceptibility to HNC (Montrer MMP8 Protéines), particularly among Asians, mixed population, and never-smokers.

  9. CYP2E1 rs2031920 and COMT (Montrer COMT Protéines) rs4680 are not major contributors to lung cancer risk.

  10. Single nucleotide polymorphism in CYP2E1 gene is Associated with Breast Cancer.

Mouse (Murine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.

  2. Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (Montrer DHCR24 Protéines)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (Montrer DHCR24 Protéines)-induced liver damage

  3. CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.

  4. Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice

  5. Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (Montrer TP53 Protéines), p21, CCND1 (Montrer CCND1 Protéines), PCNA (Montrer PCNA Protéines), and BCL-2 (Montrer BCL2 Protéines) to promote liver regeneration.

  6. Studied hepatic stellate cell cytoglobin (Montrer CYGB Protéines) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.

  7. Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.

  8. The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.

  9. significant increases in Col1a1 (Montrer COL1A1 Protéines), serine/threonine-protein kinase 1, Ctnnb1 (Montrer CTNNB1 Protéines), CSRNP1 (Montrer CSRNP1 Protéines), Ddit4 (Montrer DDIT4 Protéines), Cyp2e1, and Krit1 (Montrer KRIT1 Protéines) expressions and great decreases inreceptor D2, Neu1 (Montrer NEURL Protéines), and Dhcr7 (Montrer DHCR7 Protéines) expressions following long-term exposure to TiO2 NPs (Montrer NPS Protéines)

  10. ATF4 (Montrer ATF4 Protéines) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.

Pig (Porcine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.

  2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.

Profil protéine Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1)

Profil protéine

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Gene names and symbols associated with CYP2E1

  • cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1)
  • cytochrome P450 2E1 (CYP2E1)
  • cytochrome P450 2E1 (PTRG_07411)
  • Cytochrome P450 2E1-like (LOC100342572)
  • cytochrome P450 2E1-like (LOC100727914)
  • cytochrome P450 2E1-like (LOC101843716)
  • cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1)
  • CPE1 Protéine
  • Cyp2e Protéine
  • CYP2E1 Protéine
  • CYPIIE1 Protéine
  • P450-J Protéine
  • P450C2E Protéine

Protein level used designations for CYP2E1

cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1

GENE ID SPECIES
100066422 Equus caballus
554344 Felis catus
6345684 Pyrenophora tritici-repentis Pt-1C-BFP
100342572 Oryctolagus cuniculus
100727914 Cavia porcellus
101843716 Mesocricetus auratus
1571 Homo sapiens
415128 Canis lupus familiaris
13106 Mus musculus
25086 Rattus norvegicus
403216 Sus scrofa
282213 Bos taurus
100568285 Ovis aries
678688 Macaca mulatta
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