ACVR2A Produits
(Activin A Receptor, Type IIA (ACVR2A))
Catégories
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq, Jul 2008].
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Catégories ACVR2A en vedette
ACVR2A Anticorps
High quality antibodies with extensive validation data.
ACVR2A Kits ELISA
Reliable ELISA kits for a wide range of species.
ACVR2A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ACVR2A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
N° du produit
ABIN7438676
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN3015792
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7427552
Quantité
100 μL
Fiche technique
Fiche technique
ACVR2A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953429
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964578
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881727
Quantité
96 tests
Fiche technique
Fiche technique
ACVR2A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5569459
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305811
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305813
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ACVR2A
: "ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells." dans: Haematologica, Vol. 104, Issue 3, pp. 533-545, (2019) (PubMed).: "A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6001-6010, (2019) (PubMed).
: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." dans: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).
: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." dans: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).
: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." dans: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).
: "Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers." dans: Gastroenterology, Vol. 126, Issue 3, pp. 654-9, (2004) (PubMed).
: "Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 12, pp. 1867-71, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à ACVR2A
activin A receptor type 2A (ACVR2A), activin A receptor type 2A (acvr2a), activin A receptor type 2A (Acvr2a), activin A receptor type 2A L homeolog (acvr2a.L), activin A receptor type 2Aa (acvr2aa), activin receptor IIA (Acvr2a), actr2a, actrii, ACTRII, ActrIIa, ACVR2, acvr2, Acvr2, ACVR2A, acvr2a, rActR-II, TactrII, wu:fa02e10, XSTK9Protein level used designations for ACVR2A
- activin receptor IIA
- activin receptor type-2A
- activin A receptor, type IIA
- ACTR-IIA
- activin receptor type IIA
- type II activin receptor
- activin A receptor, type II
- activin receptor, type IIA
- ACTRIIA
- activin receptor type II
- activin type 2 receptor
- activin receptor IIa
- etID22865.9
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